Abstract:This Small Business Innovation Research (SBIR) Phase II project focuses on developing the first artificial intelligence (AI) educational software to tutor literary Braille to blind/visually impaired students. Braille is the primary medium for written communication for persons who are blind and there… more
Abstract:DESCRIPTION (provided by applicant): Improving human health by enabling the development of drugs faster and cheaper is an important part of the NIH mission. This is partially achieved by introducing and constantly improving enabling technologies. One suchtechnology is structure based drug design.… more
Abstract:ABSTRACT: Development of an operational prototype Test Data Aggregation and Analytical System (TDAAS) at Arnold Engineering Development Center (AEDC). TDAAS will address the customer"s need for data integration and knowledge discovery of Department of Defense (DoD) weapons system engine and… more
Abstract:The U.S. Navy requires a new Environmental Wideband Acoustic Receiver and Source (EWARS) sensor to facilitate the gathering of environmental data from Navy ASW platforms. The newly developed EWARS sensor must be deployable in shallow and deep environments, and be capable of operating over a broad… more
Abstract:ABSTRACT: The challenges in the operations of small unmanned aircraft systems (SUAS) and micro air vehicles (MAVs) in terms of required agility and benign flying qualities require a superior understanding of their basic flight mechanics and vehicle dynamics. Flight test data for MAVs are sparse,… more
Abstract:The purpose of this project is to integrate RE2s innovative dexterous and heavy-lift manipulation technologies with novel materials and leading-edge actuation technology to provide a Highly Dexterous Manipulation System (HDMS) with 1) the strength to lift a 120-pound 155mm shell, 2) the agility to… more
Abstract:Robotic systems have enabled U.S. Forces to respond and adapt to a rapidly changing battlespace in Iraq and Afghanistan. In the present conflict, Improvised Explosive Devices (IEDs) have been used by the enemy to attack Allied soldiers, government leaders, local police, and civilians. As IED tactics… more
Abstract:RE2 will perform research into high-performance, cost-effective actuation and leverage its Phase II Dexterous Manipulation System (DMS), its Imitative Controller, and its newest Highly Dexterous Manipulation System (HDMS)to develop and demonstrate an advanced, cost-effective, dual-arm system for… more
Abstract:ABSTRACT: A hybrid computational Electromagnetic solution will be developed that combines techniques in order to handle far-field propagation, near-field interactions, and detailed interactions with complex objects, such as human anatomical models, while taking advantage of the computational power… more
Abstract:ABSTRACT: A new thermal response module will be developed for the XFdtd electromagnetic full-wave solver, building on versions that were available in prior releases of the software to incorporate accuracy and new features from the latest approaches in the technical literature. A user-friendly… more
Abstract:The ability to model complex systems relevant to EW defeat scenarios requires a knowledgeable user to decompose analyses into a set of individual phenomena for separate analysis. There are no end-to-end models that can appropriately model all aspects of the problem and coherently bring them… more
Abstract:Project Summary/Abstract Cardiovascular disease remains the leading cause of morbidity and mortality for both men and women, accounting for nearly 40% of annual deaths. High levels of LDL-C and low levels of HDL-C are well-known risk factors for heart disease. Although lowering low-density… more
Abstract:DESCRIPTION (provided by applicant): Influenza and other infectious diseases are a major cause of death in the US and world-wide. Vaccination is the most cost-effective strategy to prevent these diseases. Although much progress has been made in vaccine technology, the timely design, validation and… more
Abstract:Project Summary/Abstract Thrombosis is a primary cause of death in the US and developed world. Fatal or debilitating blood clots occur in the three major diseases of the western world: heart attacks, stroke and cancer. Two of the major drugs used therapeutically to prevent blood clots are in the… more
Abstract:There is currently a need for fast, high voltage power electronic modules that are capable of switching at very short pulse widths to replace old-technology slower thyristors in pulse power systems. For lack of better suited switches in the market, high-voltage IGBT modules are currently being… more
Abstract:The Electric cell-substrate impedance sensing (ECIS) technology provides an excellent miniaturized platform on which to design and execute non-invasive and label-free specialized biological assays to continuously monitor cellular parameters such as viability, adhesion, and proliferation in a high… more
Abstract:Capacitors are critical components in power modulator systems for radio frequency accelerator technology, in power electronics in electric vehicles, wind energy, and photovoltaic panels, and in directed energy weapon systems. Current capacitors have low energy density and occupy 30-50% volume of the… more
Abstract:DESCRIPTION (provided by applicant): It was estimated by the World Health Organization (WHO) that there are about 314 million people who are visually impaired with 45 million of them are blind . Only 26% of working-age blind people are employed in the US and the high unemployment rate due to… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project develops an automated, software-based analysis methodology that enables yield and quality improvement of integrated circuits (ICs) through information extraction from test measurement data. Deriving actionable information from test data… more
Abstract:To assure satisfactory cooling for future JSF upgrades, the proposed solution is a vapor compression refrigeration system packaged with both a pumped PAO cooling loop and a thermal energy storage (TES) system in a standard avionics rack for the JSF. The vapor compression system, VCS, will… more
Abstract:The proposed effort will seek to design and develop vacuum brazed high density folded-fin modular heat exchangers. The scalability of these heat exchangers would provide a means for fabricating large area high performance cold plates by joining via friction stir welding. Friction stir welding is a… more
Abstract:In austere environments, erosion and corrosion seriously degrade the performance of airfoils in fan and compressor sections of gas turbine engines. To prevent damage to titanium airfoils, a powder metallurgy approach will be taken that produces a hard, erosion resistant leading edge. The leading… more
Abstract:Rapid Virulence Factor Discovery System (RVFDS) is virulence factor-discovery platform in which all of the genes of a pathogen are expressed generating a random expression library (REL). The REL is then screened for the presence of potential virulence factors with an array of pull-down assays that… more
Abstract:The traction (friction) of a tribological contact under low EHD film thickness relative to the surface roughness of the contacting pair is significantly influenced by the surface roughness. A reduction in roughness toward a superfinished surface reduces the traction coefficient. Gear efficiency… more
Abstract:Diode pumped alkali lasers have the potential to provide the required high efficiency for a laser-based missile defense system. However, traditional anti-reflective coating materials are not resistant to the alkali vapor environments associated with such systems, contaminating and degrading rapidly… more
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