Abstract:DESCRIPTION (provided by applicant): Hernial repair is the most frequent operation in general surgery for which synthetic meshes are commonly used in repairing abdominal defects. Frequently used meshes consist of non-absorbable polymers such as polypropyle
ne, polyethylene terephthalate, or… more
Abstract:This Small Business Innovation Research (SBIR)Phase I project is focused on commercializing a new gas separation product that will use ambient temperature air at low pressures to enrich it's oxygen content from 20% to 30%. By using a new plastic that separates the components of air, this process… more
Abstract:SET, Inc. proposes to develop lattice-matched AlInN/GaN HFET structure on free-standing GaN substrate. By employing native low-defect GaN substrates and by using lattice-matched heterostructures with the incorporation of indium, we expect dramatic enhancement of these HFET in power density,… more
Abstract:SETI proposed to develop the growth technology for lattice matched AlInN/GaN heterostructures and demonstrate the potential of this technology for high power, high frequency HFET RF power amplifiers. In Phase I, we successfully demonstrated MEMOCVDr growth of AlInN/GaN structures with Ga-free AlInN… more
Abstract:This Small Business Innovation Research Phase I project will develop innovative edge emitting superluminescent light emitting diodes (SLED) and laser diodes (LD) with emission in the UV-B spectral range (280 nm to 320 nm). A variety of optical sensing applications that require high power density… more
Abstract:We propose to develop a compact solid-state RF power limiter using III-Nitride technology fully compatible with that of other III-Nitride RF components (power amplifiers, RF switches etc.) The proposed limiter is based on the SET Inc. proprietary insulated gate device (MOSHFET) design and technology… more
Abstract:This Small Business Innovation Research Phase II project will develop and commercialize next-generation high-power deep ultraviolet light emitting diodes (DUV LEDs) with high quality p-type doped AlInGaN layers via migration-enhanced metal-organic chemical vapor deposition (MEMOCVD). DUV LEDs… more
Abstract:This SBIR Phase I project will establish a commercial water disinfection system based on the use of light emitting diodes that would be appropriate for use in residential settings. The Phase II effort will redesign the system so that the removal efficiency may be enhanced and the packaging of the… more
Abstract:We propose developing, manufacturing, fielding and validating environmentally friendly, energy efficient revolutionary ultraviolet irradiation devices (UID) to improve nutritional value of greenhouse crops. UIDs will be based on a new technology to produce deep ultraviolet semiconductor Light… more
Abstract:Our innovation is a low-cost method for removing orbital debris. We propose to remove debris from medium and high Earth orbits, as well as from LEO, and do it much more cheaply than conventional rockets. Our approach uses a combination of propellantless and high-Isp propulsion and high-power solar… more
Abstract:DESCRIPTION (provided by applicant): A major cause of morbidity and mortality in cardiovascular surgery is excessive bleeding post- operatively, which is commonly managed by pharmacologically modifying clot degradation (fibrinolysis), through inhibition of plasmin activity (PLact). However,… more
Abstract:XRD Inc. will deliver a feasibility study and work plan to produce engines operating on heavy fuel that meets the objectives of Program Solicitation entitled "Small Engines designed for High Efficiency, High Power Density and Quiet Operations". The goal is to have power density greater than 1 hp… more
Abstract:DESCRIPTION (provided by applicant): There is a growing body of evidence that implicates the protein kinase Pim-1 as a major driver of prostate cancer progression, and perhaps response to chemotherapy. Pim-1 is overexpressed in early prostate intraepitheli
al neoplasia and metastatic prostate cancer… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project will address the problem of a multifunctional wide band-gap aluminum gallium nitride single crystal substrate that will enable low-defect,… more
Abstract:This Small Business Innovative Research Phase I project is to develop a commercial growth process for single crystals of KBe2BO3F2 (KBBF) using hydrothermal techniques. KBBF shows exceptional promise as a deep UV non-linear optical material (NLO). NLOs are vital for the development of solid-state… more
Abstract:DESCRIPTION (provided by applicant): Acid ceramidase (AC) has been implicated as a novel target for cancer therapy because of its pivotal role in regulating interconversion of three key bioactive lipids; ceramide (Cer), sphingosine (Sph) and Sphingosine-1-
Phosphate (S1P). It is well known that Cer… more
Abstract:DESCRIPTION (provided by applicant): Long term preservation is crucial as an enabling technology for regenerative medicine products that contain living cells. However, while cryopreservation works well for most cells, some cells are more sensitive and hard
to cryopreserve by freezing. Plus, the… more
Abstract:DESCRIPTION (provided by applicant): The long term goal is the development of better, longer hypothermic storage conditions, using novel insect antifreeze proteins, for liver transplants than is currently possible in clinical practice. The use of hypotherm
ia as the principal means to suppress… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project will develop a gas sensor technology that is both highly sensitive and selective, with a rapidity and accuracy not yet seen in commercially available technologies. This will develop an integrated high performance, low cost, and… more
Abstract:DESCRIPTION (provided by applicant): For over three decades, High-Resolution (HR) Nuclear Magnetic Resonance (NMR) has been a leading analytical technique for structure and function elucidation of molecules of all types, large and small, in homogeneous sys
tems. More recently, Magic Angle Spinning… more
Abstract:Advanced Core Technologies brings three advanced competencies together to support a successful research effort required to identify, foster, and deploy technologies promising reliability enhancing materials and manufacturing innovations. Self-learning search methods, sophisticated information… more
Abstract:The goal of this SBIR Phase II project is to test develop high-strength, low-cost fibers for protective clothing and equipment, shelters and airdrop equipment using commodity olefin polymer materials in a unique fiber production process.
Abstract:Development of a software tool capable of predicting crack growth in structures with complex geometries for accurate structural life predictions and residual strength assessment is proposed. The custom crack growth simulation tool, CRACK3D, will be used as the basic code for further development and… more
Abstract:This Small Business Innovation research Phase I project is to develop flexible, elastic, superhydrophobic surfaces with a technology that physically transforms surfaces by molding microstructures into base polymers, ceramics or metals on a large scale. Uniquely the surfaces may be highly elastic and… more
Abstract:There are often major economic and logistical challenges in getting woody biomass out of the forest or off the farm in a manner, which justifies the costs of harvesting and transportation. Raw cellulosic biomass, woody or otherwise, is moist and bulky, which limits its cost-effective transport to… more
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