Abstract:DESCRIPTION: Despite extraordinary advances in proteomic technologies, we are still very far from realizing the full potential of protein biomarkers for clinical diagnostics. The FDA-approved list of clinically useful protein biomarkers numbers in the low100s, and the rate of FDA approval has… more
Abstract:DESCRIPTION (provided by applicant): Advances in molecular technologies over the past few decades have led to the development of very powerful tools to purify and analyze nucleic acids. Current processes to study RNA transactions such as transcription, translation and processing (e.g., Northern blot… more
Abstract:DESCRIPTION: Vapor intrusion is the migration of volatile organic chemicals from below ground into overlying buildings and is a major cause of large population exposure to hazardous chemicals. To assess health impacts of exposure to vapor intrusion compounds, monitoring of indoor air is required. … more
Abstract:Folic acid is a water-soluble vitamin that serves as a cofactor in 1-carbon transfers required for DNA replication. Humans lack the enzymes to synthesize folate, so dietary intake is necessary. Its deficiency is associated with neural tube defects (NTDs) in fetuses. The global burden of folate… more
Abstract:DESCRIPTION (provided by applicant): Improving statistical methods to provide better inferences and new analytical capabilities for categorical regression models would be invaluable to the medical and health-related research communities. Presently, singleregression models are used extensively to… more
Abstract:ABSTRACT: During the course of the Phase I project, the university partner Lehigh University invented a unique and highly efficient phase shifter concept based on metamaterial design concepts. This novel phase shifter unit cell allows switching between left-handed and right-handed transmission… more
Abstract:There is a clear gap between commercially available UHF tunable filters and the technology needs of current military communication systems. MEMtronics Corporation, teamed with Purdue University, intend to develop and commercialize technology that fills this gap. The intent of this Phase II project… more
Abstract:We will develop and demonstrate the key elements in a novel alternative method of fabrication of the heaters for dispenser types cathodes. The current methods depend on a wire that may soon not be manufactured anymore. The proposed method, radically alters the manufacturing approach introducing a… more
Abstract:DESCRIPTION (provided by applicant): The Specific Aim of this proposal is to test the feasibility of using a novel method of enhancing neuroplasticity for the purpose of producing clinically significant improvements in the ability of stroke patients to perform their activities o daily living (ADLs)… more
Abstract:Roll to Roll (R2R) printing, or web printing involves the patterning of flexible materials such as plastics or metal foils. R2R processing is in use today by industry and many R2R processes already exist for etch and deposition. However R2R patterning of arbitrary patterns with thin residual layer… more
Abstract:This Phase I SBIR program will define the requirements and the development plan for a broadband monolithic microwave transceiver integrated circuit which will enable the production of the next generation of precision end-game proximity sensors suitable for deployment on low-cost high-volume… more
Abstract:Mustang proposes to develop innovative, low Size, Weight, and Power (SWaP) Digital Receiver Exciter (DREX) technologies needed for simultaneous operation of the U.S. Navy Fire Scout Radar Autonomous Collision and Avoidance System (RACAS) and Coherent Automatic Radar Periscope Detection and… more
Abstract:ABSTRACT: Mustang Technology Group, LP is proposing a Phase I SBIR study that will expand the capability of air delivered weapons by providing a low cost, small form factor, multi-function radar seeker which has a flexible architecture which supports multiple radar modes and high speed data link… more
Abstract:Attaining rapid transportation of samples 50-1000 miles in an austere environment requires air transportation. Past applications have included UAV"s which transport the sample to selected location and drop the sample via guided parachute These systems can be quite accurate but they are… more
Abstract:The benefits of concentrated photovoltaic (CPV) systems with regard to total system efficiency are well known in commercial applications and operate at system efficiencies near 30% with some demonstration systems operating above 40%, compared with 15-20% peak efficiency for conventional PV. Because… more
Abstract:Anti-Tamper systems are designed to prevent and/or delay the exploitation of critical technologies. One of the major tools for reverse engineering is x-ray imaging, often used with computer-aided tomography to enable 3-dimensional information gathering of an IC structure. Thus, a device which can be… more
Abstract:Diagnostic characterization of tailpipe emission of nitrogen oxides (NOx) is becoming increasingly important as environmental concern and government regulations are requiring the use of complex NOx monitoring and destruction schemes, especially in diesel fueled engines. As these… more
Abstract:Selection of the Plasma-Facing Component (PFC) material composition is a primary consideration in future fusion reactor design. The PFC materials must not only withstand the harsh operating conditions of the reactor, but the amount of tritium uptake experienced by the PFC during… more
Abstract:Rapid evaluation of ocular injuries in austere environments requires the acquisition and transmission of visual examination data by relatively unqualified individuals due to the lack of qualified ophthalmologists or optometrists in many remote, hostile, or disaster regions. In order to be useful for… more
Abstract:Mitigation, correction, or cancellation of the deleterious effects of atmospheric turbulence on wide field of view (WFOV) imagery is desired to increase the efficiency and accuracy of visual tasks performed at a distance. With recent advances in optical components, coatings, microfabrication, and… more
Abstract:Thermophotovoltaic (TPV) energy conversion produces electrical power from heat energy using, in its most basic form, a thermal emitter and a photovoltaic converter. Since these systems typically have no or few moving parts, they provide a long term maintenance-free power generation. Key factors… more
Abstract:US troops and equipment are increasingly at risk for irradiation by lasers, whether it be from enemy targeting and ranging systems, designators, or high-energy lasers as weapons themselves. Countering the threat requires detection of the incident laser radiation, the direction from which it is… more
Abstract:ABSTRACT: Military space assets can have special constraints in form factor and function. For example, fluid cooling systems normally used for electronics and sensor cooling suffer numerous drawbacks in space applications. Conversely, compact, solid-state thermoelectric devices provide many… more
Abstract:DESCRIPTION (provided by applicant): The ability to print full-scale tissue analogues with realistic look, feel, and material properties directly from medical imaging data would have wide application in the MedSim market including planning and rehearsing patient-specific surgical cases,… more
Abstract:The feasibility of development and production of lightweight nonwoven fabric for parachute cloth application was clearly demonstrated during the SBIR Phase I project. The nonwoven fabrics made during the Phase I project had comparable strength and air permeability as that of the current woven nylon… more
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