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Displaying 126 – 150 of 1371 Awards
Company: ISOMARK, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Isomark LLC has developed a breath-based early detection technology (comprised of biomarkers and instruments for detection) that can pinpoint the onset of acute systemic inflammation. Isomark's breath biomarkers may provide an indicator of neonatal health.… more
Company: Intraband LLC Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: The technical objectives of this proposal are: 1) the design of 3.8-4.2 micron-emitting, active-photonic-crystal (APC) quantum-cascade (QC) lasers by using passive phase-locking in a monolithic structure in order to achieve multiwatt-range, diffraction-limited powers; and 2) the development of the… more
Company: Filament Games Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project will enhance learning gains among historically underachieving middle school students via a Physical Science game that aligns with a standards-based print curriculum and utilizes principles from the Universal Design for Learning (UDL)… more
Company: PhylloTech Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research Phase I project will investigate the feasibility of producing spider silk fibroins in plant trichomes. Synthetic spider silk has great potential as an environmentally-friendly biomaterial because it is very flexible yet has a tensile strength greater than… more
Company: NovaScan Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to bring to market a hand-held probe used by the surgeon to ascertain that the surgical wound and regional lymph nodes are clear of cancer. This technology will provide a highly innovative, rapid and accurate device for detecting… more
Company: NCD Technologies Agency/Program/Year/Phase: NSF / STTR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel, commercially-viable, hybrid system that improves the adhesion of nanocrsytalline diamond (NCD) coatings to tungsten carbide (WC) cutting tools. A new hybrid system will be assembled, tested, and optimized.… more
Company: Alpha Universe LLC Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project has the goal of creating a signal amplification system that, while being inexpensive and simple to use, can be combined with antibodies or other probe molecules, and can increase detection limits of conventional ELISAs by 100- to… more
Company: AQUAMOST, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): AquaMost is developing a water treatment device based on a technology called photoelectrocatalytic oxidation (PECO). The focus for this project is using PECO systems to treat groundwater contaminated with organic pollutants released from leaking underground… more
Company: BELLBROOK LABS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Post translational modifications (PTMs) such as phosphorylation, glycosylation and methylation play a central and ubiquitous role in cellular signal transduction, and the enzymes that catalyze these reactions such as kinases and methyltransferases are the targets… more
Company: STEMINA BIOMARKER DISCOVERY, INC. Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project will fund a continuation of breakthrough research, development and commercialization of an in vitro assay to help prevent birth defects. This innovative product is driven by a need to create a test for human developmental toxicity that… more
Company: CENTROSE, LLC Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research Phase I project highlights a strategy for the development of the first integrated high throughput pipeline to synthesize and evaluate novel sugar-drug conjugates. The core innovation of this proposed phase I study is an enzyme catalyzed one-step glycosylation… more
Company: CENTROSE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Non-small cell lung cancer (NSCLC) is among the most common and lethal cancers yet, the current standard of care for advanced stage NSCLC provides only modest improvements in overall survival or quality of life. Thus,there exists a significant unmet need for new… more
Company: BIOSENTINEL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most toxic substances known to humans, causing respiratory failure. Because of their lethality and ease of production, the Department of Defense (DoD) designates BoNTs as a categoryA bioterrorism agent. Developing effective,… more
Company: BIOSENTINEL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNT) are the most toxic substances known to humans, causing respiratory failure upon intoxication. Despite their lethality, BoNTs have clinical health and cosmetic applications and are currentlyFDA-approved for treating cervical dystonia,… more
Company: CENTER FOR PSYCHOLOGICAL CONSULTATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The need for evidence-based mental health treatments i.e., 'treatment based on the best available science or research evidence , has been stressed from scientific, ethical, and marketing perspectives. While empirical evidence supports both the efficacy and… more
Company: CENTER FOR PSYCHOLOGICAL CONSULTATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Psychiatric comorbidity is a major concern for adolescents with substance use or psychiatric disorders. Eighty-five percent of adolescents in treatment for a substance use disorder have an additional psychiatric comorbidity. Similarly, psychiatric disorders have… more
Company: CENTER FOR PSYCHOLOGICAL CONSULTATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): Autism is a neurodevelopmental disorder characterized by deficits in social reciprocity, verbal and nonverbal communication, and behavior. It is among the most prevalent of all developmental disabilities, with an estimated prevalence of 1 in 110. Early detection… more
Company: CENTER FOR PSYCHOLOGICAL CONSULTATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by APPLICANT): The need for evidence-based mental health treatments i.e., 'treatment based on the best available science or research evidence' 1, has been stressed from scientific, ethical, and marketing perspectives3. While empiricalevidence supports both the… more
Company: KASHMERICK ENGINE SYSTEMS LLC Agency/Program/Year/Phase: DOD / SBIR / 2011 / 2
Abstract: The proposed Phase II program seeks to demonstrate the feasibility of a patent-pending 6-cycle continuous combustion engine system technology that is a modification of existing 4-cycle engines to address engine related concerns in small generators as experienced by the United States Marine Corps and… more
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project is aimed at developing an effective, inexpensive, safe means of controlling diseases in farm-raised catfish. One of the biggest problems in farm-raised catfish is disease that occurs in commercial ponds. Scientists at Auburn University… more
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Microfluidic systems are emerging as critically important tools for high throughput cell based analysis for applications including genotyping, sequencing, gene expression analysis, nucleic acid amplification, and diagnostics. Lab-on-a-chip devices that are… more
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The regulation of gene expression drives all biological processes. A thorough understanding of the mechanisms governing the patterns of gene expression is necessary to understand the fundamentals of biology and the complexities of cancers and other diseases. The… more
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): There is societal need for new therapeutic agents in our arsenal of defenses against bacterial and fungal pathogens, many of which are increasingly resistant to existing antibiotics. Filamentous fungi are considered promising resources for the development of… more
Company: Micro Optics Technologies, Inc Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1
Abstract: A system is designed to extract energy from background RF energy in the ambient due to radio and wireless communication sources. This energy is harvested on a continuous basis and stored on-board to provide power for anti tamper systems. This eliminates the need for maintenance of battery sources… more
Company: NOVASHIELD, Inc. Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: The number of distinct malware being released into the wild is growing at an alarming rate. Some IT security companies are seeing more than 5,000 new malware instances each day. IT security companies can no longer keep pace with this deluge using manual, labor-intensive malware analysis techniques… more
Displaying 126 – 150 of 1371 Awards
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