Abstract:DESCRIPTION (provided by applicant): Over the last decade, bacterial and archaeal communities have been identified in virtually every ecological niche examined, from acid mine drainage to tropospheric clouds to the human body. Understanding the make-up andinteractions within these communities is… more
Abstract:ABSTRACT: ORBITEC proposes to develop and synthesize a safe, high performance, high density solid oxidizer to replace Ammonium Perchlorate (AP) in solid propellants for use in booster, tactical, and strategic systems. The long sought replacement for ammonium perchlorate remains an unanswered… more
Abstract:ABSTRACT: ORBITEC proposes to develop and demonstrate a family of Low-Cost Thrust Chambers (LCTC) for use in future NASA exploration systems. Substantial cost savings will be realized in the production of the LCTCs with ORBITEC"s innovative hybrid fabrication technique. Hybrid fabrication… more
Abstract:ORBITEC proposes to develop high strength cast aluminum alloys for use in Expeditionary Fighting Vehicle (EFV) structures. Using a new casting technique developed by MSOE, the cast alloys HPAC structures will achieve material properties similar to those of forged structures. The casting process is… more
Abstract:ORBITEC proposes to develop the Recoilless Launcher Propulsion System (RLPS), a means of propelling a warhead from a shoulder-mounted recoilless launcher which will greatly reduce the risks posed to the operator by the back blast from such launchers, including over-pressure, high sound levels, and… more
Abstract:ABSTRACT: ORBITEC proposes to demonstrate and validate a laboratory-scale experimental injector stability screening technique which will quantify injector element stability characteristics. The experimental approach promises to dramatically reduce development cost by utilizing a gaseous single… more
Abstract:C5-6 Technologies and University of Wisconsin Stevens Point scientists will develop a bacterial strain that economically ferments sugars into isoprene, a platform chemical that will play a central role in the future bio-economy. UWSP scientists have genetically engineered E. coli to produce isoprene… more
Abstract:DESCRIPTION (provided by applicant): Improved therapy has transformed cystic fibrosis (CF) from a disease characterized by death in early childhood to a chronic illness with a median survival of approximately 30 years. However, there is still no cure for this devastating genetic disease affecting… more
Abstract:The objective of this phase I STTR project is to develop and demonstrate a roll-to-roll process for printing semiconductor and metal nanostructures with lateral dimensions as small as 100 nm on flexible substrates. systeMech will collaborate with the University of Wisconsin-Madison (Prof. M.G.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a novel software technology for practical clinical use that can evaluate dynamic ultrasound images to accurately interpret changes or pathologies in soft tissues, such as tendons and ligaments. Today, a radiologist… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to significantly advance H2 gas sensing technologies by exploring a novel nanohybrid sensing platform of SnO2 nanocrystals supported on carbon nanotubes (CNTs). The high demand of H2 as a clean energy source drives the fast growth… more
Abstract:This Small Business Innovation Research Phase I project targets multifunctional meta-materials having acoustic impedance equal to tissue and optimized for solid-state tactile sensing. Optimized multifunctional performance of these newly developed meta-materials includes enhanced mechanical, acoustic… more
Abstract:A bi-stable meta-material which rejects high amplitude harmful sound but transfers sound levels needed for the situation awareness is proposed. A threshold intensity of the sound is determined by the material design and is set to 90 dBA all signals exceeding this level will be attenuated at least… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project is aimed at developing an integrated system to stabilize a conventional high-end, inverted optical microscope to the precision required to routinely achieve the imaging power of emerging super-resolution (SR) microscopy techniques. These… more
Abstract:This Small Business Innovation Research (SBIR) phase I aims to demonstrate the feasibility of constructing a novel machine for manufacturing low-cost glass-to-metal seals for insulating window glazing. Applications include vacuum glazing which insulates as well as a wall (R11 to R20), representing a… more
Abstract:Vacuum glazing requires a scratch-resistant Low-E coating. Microscopic pane spacers are required to prevent the two panes from touching under external pressure, but create high contact stresses which can scratch glass and existing Low-E coatings during pane movement with temperature change. Hard… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project is to investigate the feasibility of new game-based software in which youth play the roles of adult professionals. This approach has demonstrated the potential for raising knowledge of and interest in civics and the local community for… more
Abstract:Computation of the radiative transfer model for a hyperspectral sounder with thousands of spectral channels is very time-consuming. Consequently, operational data assimilation systems can assimilate only a few hundred channels. The radiative transfer model is very suitable for GPU implementation to… more
Abstract:Purpose: Prior research demonstrates that younger students who are low- or non-verbal often have difficulty independently practicing skills that provide a foundation for early literacy. The proposed product will provide support to students who are low- or non-verbal to independently practice phonics… more
Abstract:DESCRIPTION (provided by applicant): Estrogen receptor a (ERa) is the major therapeutic target for breast cancer, and ERa binding at target genes in breast cancer cells is guided by DNA binding pioneer factor proteins such as FoxA1. Although tamoxifen is asuccessful therapeutic for suppressing… more
Abstract:DESCRIPTION (provided by applicant): A critical unmet need in implementing personalized medicine is the ability to sort through the millions of single nucleotide polymorphisms (SNPs) present in the human genome and to pinpoint which of these DNA variations are causative in disease. A key… more
Abstract:DESCRIPTION (provided by applicant): Harmful metals not readily detoxified naturally are discharged from numerous industrial activities and pose lasting environmental hazards requiring expensive remediation efforts. This project targets profitable dilute metal removal and reclamation. Creating an… more
Abstract:Copper is a commodity essential to modern society and its production is very energy intensive. Half of U.S. copper consumption goes to electrical, heating, and plumbing infrastructure in building construction and energy use for copper production topped 43 trillion BTUs in the early 1990s. Currently… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this SBIR Phase I proposal is to establish the measurement reliability and the clinical feasibility of the RGR-GAIT instrumented gait analysis system. Gait dysfunction can dramatically affect a person's ability to perform activities of… more
Abstract:DESCRIPTION (provided by applicant): Patient socket performance is a critical barrier to progress in rehabilitation, the most common source of patient dissatisfaction and part of a growing medical and socioeconomic problem. Poor socket performance is a greatly uncharacterized multi-factorial… more
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