Abstract:Researchers at JBEI have developed a pretreatment technology using ionic liquids that efficiently extracts sugars from a combination of mixed feed stocks. Any ionic liquid used for biomass pretreatment or cellulose hydrolysis by thermostable cellulose may be… more
Abstract:…, medicines, advanced materials, and flavor and fragrance applications. Lignin, a natural biopolymer of monomeric phenol subunits, is a rich source of aromatic building block chemicals. Current biorefinery strategies primarily focused on valorization of cellulose and… more
Abstract:… so that stalks and stems remain strong). Consequently, biorefineries using this low lignin switchgrass can reduce their initial investment, lower their ongoing operating expenses, and increase their annual revenue. Low lignin switchgrass would give cellulosic biofuels… more
Abstract:Monomers and other chemical intermediates are typically obtained from non-renewable resources, specifically petroleum. Renewable resources, such as plant derived biomass, may become a significant source of these critical materials but new technology is required for their safe and efficient… more
Abstract:… processes used, and thedifficulty or inability to compost at the end of life. Academic and industrial researchers have investigated recycling petroleum-based polymers, incorporating bio-derived polymers to reduce intake of petroleum, and pure biopolymers (cellulosic… more
Abstract:… competitive with petroleum-derived phthalates. As a result of the cost, isosorbide is largely restricted to highly specialized uses in pharmaceuticals currently. This SBIR project will develop a new, low-cost chemical route to isosorbide starting from the cellulose contained… more
Abstract:…. To respond to this need, Luna proposes the development of a low-cost affinity matrix with a high surface area to provide substantial binding regions for targeted proteins of interest. This system will allow for the purification of any protein expressed with the cellulose… more
Abstract:… are essential to the national economic and environmental stability of the United States. Pathways are well established to ferment sugars derived from biomass into fuels and bioproducts. However, there is a massive gap between the physical form of raw cellulosic biomass and… more
Abstract:…ctive distillation to produce THF from a dilute aqueous solution containing furfural. Dilute solutions of furfural are commonly produced from acid hydrolysis of biomass. This process is commonly used in the paper industry and is an element of the production of cellulosic… more
Abstract:We have identified methods to produce inducers of cellulase production that will streamline the production of these enzymes for cellulosic ethanol and other applications. During Phase II of this project, we will scale up the methods, determine their applicability to commercially… more
Abstract:This Small Business Innovation Research Phase I project helps unlock the potential of forests to provide sustainable, carbon-neutral raw material for much of the nation's energy and chemical needs. Current technology cannot efficiently separate cellulose, hemicellulose and… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project will develop a facultative anaerobic bacterium that ferments sugars obtained from cellulosic sources into isoprene, a valuable feedstock used in the production of latex rubber, plastics, and pharmaceuticals. Isoprene… more
Abstract:… renewable chemical energy, has low costs (e.g., $~0.30/kg), we propose to fix CO2 to formic acid powered by sugars through a novel synthetic enzyme pathway comprising 13 enzymes. The overall stoichiometric reaction is 6 CO2 + 7 H2O + C6H10O5 (starch, Phase I; cellulose,… more
Abstract:Sustainable global economic growth requires the diversification of energy sources and chemical feedstocks away from conventional fossil fuel supplies. One way to meet this need is to convert renewable resources such as cellulosic biomass to fuels and chemicals; however a major… more
Abstract:… metagenomic DNA from sites likely to contain bacteria that produce enzymes with lignocellulose degrading capabilities. As part of our initial proof of concept for our device, we are using our device to discover metagenomic genes for enzymes that degrade cellulose… more
Abstract:… drop-in biofuels, and substitutes for other petroleum-derived materials, this research can help reduce U.S. dependence on foreign oil, reduce our carbon footprint, and spur domestic manufacturing, investment, and job creation. In addition, sourcing sugars from cellulose can… more
Abstract:Intellectual Merit This Small Business Innovation Research Phase I project takes a novel approach to produce improved maize cultivars for bioenergy applications. Lignin in cellulosic biomass creates a barrier that limits conversion of cellulose into biofuels. In the proposed… more
Abstract:… or replacement of high-density polyethylene (HDPE) shopping bags, these bags are still widely popular, with over 100 billion bags consumed every year across the U.S. alone. Lignin output is expected to increase in the ensuing years due to an increase in cellulosic ethanol… more
Abstract:This Small Business Innovation Research Phase I project will validate a novel single-chemical process called decarbonation of carbohydrates, which converts ligno-cellulosic carbohydrates to liquid biofuels as a drop-in transportation fuel. This novel process, proposed in this… more
Abstract:… of steps compared to current technologies. The innovative technology described here is based on the use of a novel microorganism isolated from Yellowstone National Park, which is able to withstand extreme acidic conditions and is capable of efficiently degrading cellulose,… more
Abstract:… metabolically superior cells for the purpose of improving biofuel production. This project will identify RNA aptamers that can selectively bind pyruvate and phosphoenolpyruvate, two essential intermediates in the metabolic pathways that generate sugar-derived and cellulosic… more
Abstract:The biomass supply chain is evolving to meet the expanding forms of biomass utilization. In particular to meet the goals to produce 60 billion gallons of renewable fuel by 2030 will require a massive increase in cellulosic biofuel production. To produce 45 billion gallons of… more
Abstract:… Research Center (GLBRC) and is the exclusive owner of intellectual property that enables biorefineries based on ionic liquids that that operate at a fraction of the cost and carbon footprint of competing technologies. Ionic liquids are true solvents for cellulose, which… more
Abstract:This Small Business Innovation Research Phase I project will develop a novel means for isolating solutes including fermentable sugars from ionic liquids. Ionic liquids are the only known solvent for woody biomass and have been shown to support the breakdown of cellulose to… more
Abstract:… value C5 sugars .in the form of high value C5 oligomers (xylo-oligosaccharides or XOs) from the hemicellulose fraction of biomass. These XOs can be marketed as a high-value functional food product. Including the production of XOs to the production of VFAs from the cellulose,… more
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