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Displaying 51 – 75 of 232 Awards
Company: Los Gatos Research Agency/Program/Year/Phase: DOE / SBIR / 2008 / 2
Abstract: …, moderating climate warming. In laboratory experiments, sulfate aerosol formation depends, in a strong, non-linear manner, on ammonia concentrations. There are limited field-studies, and uncertainties are partially responsible for limitations in predicting aerosol nucleation… more
Company: ONE CELL SYSTEMS, INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: … of cellular development, gene expression or protein composition within the hematopoietic microenvironment have been difficult because of the relatively low cell frequency of megakaryoctyes: megakaryocytes represent only 0.015% to 0.03% of the total number of nucleated… more
Company: Physical Optics Corporation Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: … they are not performed on all pregnant women. As a result, a large number of fetal genetic abno rmalities, such as Down syndrome, are missed. Reliable methods of noninvasive prenatal diagnosis have long been sought in perinatal medicine. The presence of fetal nucleated red… more
Company: RAINDANCE TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2008 / 1
Abstract: …e candidate protein solution to different degrees of supersaturation for variable durations and t hen reduces the supersaturation to a low value. The concept is to find the two-step kinetic pathway that firstly quenches the drop for the right amount of time to nucleate just a… more
Company: SNOWDON PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: …loid diseases are characterized by transformation of proteins from their proper native structure into an abnormal beta-rich structure known as amyloid fibril. This process is triggered by short peptide segments within the pol ypeptide sequence called core nucleation motifs that… more
Company: TOPOGEN, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: … anticancer agents and a number are FDA approved. Anti-topoisomerase therapy is predicated on subverting the endogenous topoisomerase into a genotoxic, DNA damaging ag ent. A significant problem with such drugs is collateral damage in normal cells. Since all nucleated… more
Company: VEXTEC Corporation Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: Our commercial and military fleets operate safely but at a great cost. Downtime for structural inspections, elaborate sustainment equipment, long maintainer hours, expensive in-depot repair, continuous spectrum monitoring, and extensive component testing have effectively reduced the rates of… more
Company: VISTA ENGINEERING & CONSULTING, LLC Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: … that make it environmentally stable, an excellent moisture barrier, and nonvolatile. These unique properties of the POSS feed stock present an unusual opportunity to the electronics industry; a conformal coating that also actively mitigates tin whisker nucleation and… more
Company: ADLYFE, INC. Agency/Program/Year/Phase: DOD / SBIR / 2007 / 2
Abstract: …abeled Pronucleon peptides that undergo conformational change in the presence of the misfolded infectious prion protein. The conformational peptide change is propagated throughout the ensemble of sequence specific Pronucleon peptides in the reaction via a nucleation event… more
Company: AMERICAN SUPERCONDUCTOR Agency/Program/Year/Phase: DOD / STTR / 2007 / 2
Abstract: … of 450 A/cm-width. This performance is equivalent to a current of 200 A in an industry standard 4.4 mm wide Second Generation (2G) superconducting wire. To achieve this successful result, the Phase I program focused on the characterization and optimization of the … more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / STTR / 2007 / 1
Abstract: … method/s. The method consists of (a) Colloidal synthesis of CdTe nanocrystals, (b) Nanocrystalline film deposition by spin coating and (c) Chemical treatment of the film to remove the ligands and passivate the surface. MOCVD will be used first to nucleate, selectively… more
Company: Crystal IS, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2007 / 1
Abstract: … non-polar nitride crystals. Epitaxial growth optimization on non-polar substrates will be extensively investigated to produce device quality films and heterostructures required for high performance, long lifetime devices for next generation X-band radar system. Nucleation… more
Company: DXE LLC Agency/Program/Year/Phase: DOD / SBIR / 2007 / 1
Abstract: … health prediction in order to address this very issue. One way of accomplishing this is by developing methods to predict fatigue. This study will focus on measuring surface roughness of critical aircraft components and correlating it to fatigue crack nucleation. DXE, LLC.… more
Company: Fracture Analysis Consultants, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2007 / 2
Abstract: … where cyclic loading leads to contact and slip between mating parts. For instance, the disk/blade assemblies in turbine engines suffer fretting at the dovetail contacts. In the proposed analysis methodology, an analytical model of fretting fatigue crack nucleation based on… more
Company: Integrated Sensing Systems Incorporated Agency/Program/Year/Phase: NSF / SBIR / 2007 / 1
Abstract: …nous drug lines is critical to preventing air embolisms and even death. Two-phase detection and damping problems have been reported in macroscopic Coriolis mass flow meters and in MEMS-based resonant tubes. There are experimental indications that microbubbles may be nucleating… more
Company: Kopin Corporation Agency/Program/Year/Phase: NSF / SBIR / 2007 / 1
Abstract: … of thermodynamically unstable InGaN alloy compositions. While the synthesis of high quality InN has proven challenging via standard growth techniques such as metalorganic chemical vapor deposition (MOCVD), our preliminary investigations have confirmed that InN nucleates… more
Company: Los Gatos Research Agency/Program/Year/Phase: DOE / SBIR / 2007 / 1
Abstract: … to depend in a strong and non-linear manner on ammonia concentrations. However, these processes are only starting to be studied in the field, and the remaining uncertainties are partially responsible for current limitations in the prediction of aerosol nucleation. An… more
Company: Luminit, LLC Agency/Program/Year/Phase: DOD / SBIR / 2007 / 1
Abstract: To address the DARPA need for airframe crack nucleation prediction through surface roughness measurement, Luminit, LLC proposes to develop a new Fiber-Image-Guide Airframe Roughness Profilometer (FIGARP), based on a novel phase resolvable full-field optical coherence tomography… more
Company: QuesTek Innovations LLC Agency/Program/Year/Phase: DOD / STTR / 2007 / 1
Abstract: … high performance gear steels will be measured and modeled. The goal will be to assess the feasibility of achieving a sufficiently gradual transformation to serve as a desired "state signature" of fatigue lifetime. In parallel, the 3D characterization of nucleation sites and… more
Company: Southwest Sciences, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2007 / 1
Abstract: … of other atmospheric trace species on the spectral ammonia peak. Commercial Applications and other Benefits as described by the awardee: By contributing to the identification of aerosol particles, and by providing information on how these particles nucleate and grow,… more
Company: Texas Research Institute Austin, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2007 / 2
Abstract: The proportion of fatigue life that is expended during fatigue crack nucleation is significant in the materials and loading typical of aircraft structural components. The ability to measure or compute the time for fatigue damage to nucleate active fatigue cracks allows the… more
Company: VISTA ENGINEERING, INC. Agency/Program/Year/Phase: NSF / SBIR / 2007 / 1
Abstract: …, crack resistant, transparent to X-rays and structured on a submicron scale. Furthermore, applications in lithography-pattern stamps require similar rigorous abrasive wear on submicron sized features. The objective of this SBIR is to investigate NSD nucleation, strength,… more
Company: Aerodyne Research, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2006 / 1
Abstract: … process of aircraft plume aging. Under this program, standard plume dilution profiles will be identified and a prototype sampling system that captures the salient aspects of this dilution process will be built. Initial feasibility tests of mixing and sulfate nucleation in the… more
Company: Fracture Analysis Consultants, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2006 / 1
Abstract: … where cyclic loading leads to contact and slip between mating parts. For instance, the disk/blade assemblies in turbine engines suffer fretting at the dovetail contacts. In the proposed analysis methodology, an analytical model of fretting fatigue crack nucleation based on… more
Company: IONWERKS, INC. Agency/Program/Year/Phase: DOD / STTR / 2006 / 2
Abstract: … The Phase II will be aimed at the implementation of laser photoionization coupled with optical techniques for more complete in situ time-resolved characterization of both inherently ionized and neutral fractions of the ablated growth precursors. Mechanisms of nucleation and… more
Displaying 51 – 75 of 232 Awards
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