Abstract:A continuing and growing threat to U.S. military personnel and civilians is exposure to toxic chemicals and pathogens. Useful detection systems exist, but it remains imperative to investigate next-generation technologies that have the potential to improve by an order of… more
Abstract:DESCRIPTION (provided by applicant): More than 43,000 Americans die each year from liver disease, making it the 10th leading disease- related cause of death in the US. Cirrhosis with irreversible injury and scarring of the liver is the most prevalent causeof liver failure and is attributable to… more
Abstract:DESCRIPTION (provided by applicant): There is a worldwide consensus that islet transplantation may be considered a viable option for the treatment of insulin-dependent diabetes mellitus, and clinical trials are underway at many centers around the world. Asthis approach for curing diabetes… more
Abstract:DESCRIPTION (provided by applicant): Twenty four million Americans are affected with end-stage lung disease which is the 4th leading cause of death in the US, and there are currently 2,122 candidates on the lung transplant waiting list. Emphysema and chronic obstructive pulmonary disease are the… more
Abstract:DESCRIPTION (provided by applicant): Vascular grafting is performed clinically to repair or replace diseased coronary artery and peripheral vessels to restore normal blood flow patterns. Synthetic grafts composed of polymers such as Dacron and expanded polytetrafluoroethylene do not work well in… more
Abstract:… of generating all current and future signals (CA, P, M, L2C, L5, Jammer waveforms,GNSS, etc.) is proposed. CRS has developed a modern wavefront simulator for all GNSS signals.This proposal details adapting the simulator to meet MDA objectives and optimize the system for… more
Abstract:…. TRS will utilize PMN-PT single crystal piezoelectrics, which have inherent advantages over traditional materials, and integrate this with photolithographic micromachining methods to produce a device with high sensitivity and bandwidth that surpasses other systems. Bone scans… more
Abstract:TRS Technologies, Inc. proposes to develop high energy density capacitors with stable dielectric properties for utilization in pulse power systems. The proposed ceramic capacitor will combine the best features of high energy density, low dielectric loss and high reliability. … more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop an innovative, cost-effective, oil quality sensor that can detect when and how engine oil becomes degraded, as an integral part of a smart engine health monitoring system. Current sensors typically work… more
Abstract:The Defense Advanced Research Program Agency (DARPA) is currently seeking a small semi-autonomous, very high speed maritime surface munition that is capable of speeds of 100 knots or greater in sea state 4 or above. The system must have the capability to track, differentiate and… more
Abstract:NASA space exploration missions require the electronics for avionic systems, components, and controllers that are capable of operating in the extreme temperature and radiation environments of space and planetary surfaces. To design wide-temperature, radiation-hardened (rad-hard)… more
Abstract:Accurate real-time microbial monitoring of water environment is of paramount importance to crew health as well as to ensure proper functioning and control of the life support system during space exploration. The existing methods are time-consuming and labor-intensive, and the… more
Abstract:Combustion instabilities pose a significant technical risk in the development of liquid and solid rocket motors. Much of the effort in modeling combustion instabilities has focused either on systems-level tools, or use of detailed computational fluid dynamics (CFD) to simulate… more
Abstract:… the rate of data availability from a number of omics platforms such as genomics, proteomics, metabonomics and metabonomics. This has served as a driving force in efforts to develop novel predictive software tools that can model the underlying biological system by inferring… more
Abstract:Existing thermal analysis tools for optical signature generation are employed in an off-line manner, and are inadequate for new closed-loop real-time system simulations being pursued by MDA. This STTR project aims to develop and demonstrate an innovative simulation tool for the… more
Abstract:The MDA is developing satellite based systems that could benefit from ongoing developments in advanced materials for lithium ion batteries. Unfortunately, the driving applications for much of the new materials research have less abusive operational cycles than the frequent… more
Abstract:… computational codes on the next generation multicore platforms. This project will develop and deliver partitioning techniques for multicore nodes, execution algorithms, coupling techniques between the individual solvers, main memory management for the multicore systems,… more
Abstract:… and requirement analysis technologies used on the Electromagnetic Rail Gun Program, and currently being integrated into the SM-3 Block IIA/IIB design process. The following proposal presents a holistic approach to weather interaction with high speed munitions systems… more
Abstract:… various mechanisms that lead to degradation of the catalyst. The degradation mechanism will be validated and refined against the experimental results including transient pressure and temperature. In Phase II, the computational model will be extended to a two phase system… more
Abstract:… nanomaterials have demonstrated potential for widespread applications, toxicology of these materials has not been thoroughly evaluated under different exposure scenarios. We propose to develop a comprehensive software tool integrating multidisciplinary physiology and systems… more
Abstract:The process of dispensing unguided submunition projectiles from weapons systems must result in stable projectile flight with high kinetic energy and even dispersion over the target area. This project will incorporate a solid body collision methodology into the existing Loci/CHEM… more
Abstract:… joint forces. To account for fatigue and the onset of potential injury, realistic physiological and physics based muscle fatigue and injury models will be developed and validated. In Phase II, the developed software tool will be used to design an improved helmet system to… more
Abstract:…es of thermal, optical or mechanical energy harvesting, including: rapid power generation, rugged architecture for long-lasting, continuous energy scavenging at various environments, higher energy conversion, ease of packaging and integration with existing energy storage systems… more
Abstract:… would be carried out to demonstrate platform operation. We have assembled an interdisciplinary team of engineers and scientists from CFDRC and Auburn University with expertise in design, modeling, fabrication and experimental characterization of microfluidic systems for… more
Abstract:… perfusion and diffusion based conditions was highlighted. Finally, co-culture of vascular and tissue cells mimicking the in vivo conditions were demonstrated. Phase II will expand the platform to include cells from other organs of interest namely brain and kidney. Systems… more
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