Abstract:ABSTRACT: Current surface modification and lubricant technologies are either ineffective or too expensive and difficult to apply on US Air Force refueling drogue components. A low-cost, non-toxic, environmentally benign, easy to apply lubricant could significantly reduce US Air Force cost burdens… more
Abstract:At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of -… more
Abstract:We propose an Acousto-Optic Tunable Filter (AOTF) Spectropolarimetric Imaging System for Enhanced Standoff Chemical Detection at Long Wave Infrared (LWIR) wavelengths. This work entails development of suitable LWIR material, design of the LWIR AOTF, and design of the hyperspectral imaging sensor… more
Abstract:The objective of this proposal is to demonstrate the feasibility of producing light weight and thermally manageable integrated optical systems suitable for airborne and space high power directed energy applications. This project will focus on improving two of the most important parts of a high… more
Abstract:There is an acute need for low-power, low-cost, portable mid-wave infrared (MWIR) thermal imaging systems. Current HgCdTe focal plane array (FPA) detectors have high fabrication cost and require low operating temperature. Recent advances in quantum dot (Q
Abstract:The prevalence of off earth landing missions both proposed and undertaken has been steadily increasing. With the proposal of missions, not only to Mars, but also to comets, asteroids and outer planet moons, the ruggedness and robustness of equipment must meet the challenges of ever harsher… more
Abstract:The technical objective of this proposal is to demonstrate a Quantum Cascade Laser (QCL) emitting in the 3.0-3.5 & #181;m wavelength region, which employs a metamorphic buffer layer (MBL). It is the goal of this program to develop a QCL single-stripe device which will operate in a single,… more
Abstract:DESCRIPTION (provided by applicant): Otitis media (infection of the middle ear space) is one of the most common diseases of childhood. Myringotomy with tympanostomy tube (TT) insertion is the most common operation performed on children in the United States. Otorrhea is the most common complication… more
Abstract:DESCRIPTION (provided by applicant): Cochlear implants have restored hearing in thousands of patients over the last two decades. However, because residual hearing is damaged in the process of insertion, this valuable procedure has been restricted to thosepatients with profound or total deafness.… more
Abstract:DESCRIPTION (provided by applicant): Even as the cost and throughput of commercial sequencers has continued to improve over the last 5 years, there is still a need to further reduce sequencing costs, to increase throughput and sequencing accuracy and to reduce the costs associated with sample… more
Abstract:ABSTRACT ST segment myocardial infarction (STEMI) is a serious acute coronary condition that affects 500,000 Americans each year and results in significant U.S. healthcare costs ( 31B/year for acute MI treatment). STEMI mortality directly relates to the extent of the total myocardial injury and even… more
Abstract:DESCRIPTION (provided by applicant): New dosage forms are needed to address the shortcomings of current practice with regard to administration of medications to pediatric populations. Specifically, in the absence of pediatric-specific products - formulations that are both palatable (to ensure… more
Abstract:DESCRIPTION (provided by applicant): Mosquito-borne members of the Flavivirus family include four serotypes of dengue virus (DENV1-4) and West Nile Virus (WNV) and are classified as re-emerging pathogens due to the frequency and severity of recent epidemics. There are an estimated 100 million DENV… more
Abstract:DESCRIPTION (provided by applicant): The proposed project will further develop marketable ELISA and lateral-flow immunoassay diagnostics (LFI) in both monoplexed and multiplexed formats for the NIAID category A, BSL-4 filoviruses, and will drive pre-clinical development and validation for these… more
Abstract:DESCRIPTION (provided by applicant): While organ transplantation is a vital last resort therapy to treat patients with end-organ failure of the lung there is a growing waiting list of patients who are eligible for transplants as the number of suitable donor organs fall far short of the demand for… more
Abstract:Advanced pulsed power capacitors with energy densities of above 10 J/cc and high breakdown strength are required for the military of the future. While polymers such as BOPP and PET offer excellent loss characteristics, their low energy density has led to a search for alternative polymer dielectrics… more
Abstract:NASA requires instrumentation technologies that can be applied to measure flow under extreme temperatures where traditional sensing methodologies cannot be used. The proposed Phase II SBIR research effort will seek to create wall shear sensors that can be applied to measure signals at temperatures… more
Abstract:Conventional generation of a high-quality RF carrier (signal) beyond 50GHz requires high precision cavity engineering that inherently restricts contiguous bandwidth coverage. Worse, even if one were capable of fabricating a set of such stabilized, frequency-dense cavities to mimic discrete 30-120GHz… more
Abstract:Digital equalizers have been the major enablers in RF communications in terms of managing component imperfections and channel impairments. Specifically, the ever increasing processing power of the dedicating computing processors has availed a steady increase in the ability of complex communication… more
Abstract:Spectral beam combination (SBC) of fiber lasers is the most practical approach to DEW-class HELs using diode-pumped fiber lasers. Use of conventional diffraction gratings to combine wavelengths is limited in that metal is inherently absorbing. Regardless of the metal layer thickness, optical power… more
Abstract:ABSTRACT: In contrast to the NIR band, which is supported by an infrastructure of devices developed to serve telecommunication applications, the SWIR band remains out of reach for critical defense applications. While it is relatively simple to construct a low-noise oscillator within the… more
Abstract:Future NASA and commercial missions will increasingly target destinations with challenging topography and limited communication including unmapped asteroids, comets, and outer planet moons; surface rendezvous sites for sample return; and challenging sites like polar peaks, crater rims, and skylights… more
Abstract:Advances in computer-aided mission planning can enhance mission operations and science return for surface missions to Mars, the Moon, and beyond. While the innovations envisioned by this program are broadly applicable, they serve an immediate and urgent need for missions to prospect for volatiles at… more
Abstract:Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies. Ion channels have been identified by… more
Abstract:DESCRIPTION (provided by applicant): Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies.… more
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