Abstract:Agave BioSystems, with their academic partners at the Mote Marine Laboratory, proposes to develop probiotic pharmaceuticals from indigenous commensal microbes to enhance gastrointestinal health in the bottlenose dolphin (Tursiops truncatus). The dolphin gastrointestinal microbiome will be… more
Abstract:Wound management becomes increasingly challenging due to bacterial infections, especially from epidemic drug-resistant strains. To address this problem, Agave BioSystems proposes to develop a RANT (Rapidly Adaptable Nanotherapeutics) breadboard system built upon the modules successfully established… more
Abstract:Agiltron Inc. proposes to develop a compact, sensitive, and selective tunable diode laser absorption spectroscopy (TDLAS) based multi-gas sensor for OBOGS breathing oxygen monitoring. In the proposed research, novel laser diodes that output wavelength tunable from 2000 nm to 3500 nm will be used to… more
Abstract:ABSTRACT: In this program, Agiltron, Inc. and Harvard University will develop a biologically-inspired integrated sensor that can detect the UV, visible (VIS), near infrared (NIR), and mid-wave infrared (MWIR) bands. This sensor will be integrated with plasmonic filters to provide additional… more
Abstract:Agiltron proposes a new type of portable inductively coupling wireless battery charger station to relieve the logistic footprint and operation complexity of the wired power connection for charging battery-operated devices in the battlefield management. The wireless battery charger station will allow… more
Abstract:Leveraging on Agiltron"s extensive experience in fiber sensor development, we propose to develop a customized sensing system with the ability to measure fuel quantity in a collapsible tank. Based primarily on mature technologies and commercially available components, the proposed sensor system… more
Abstract:In Phase I project, by leveraging on Agiltron's experience in optical fiber components and our unique fabrication procedure of fiber array, we successfully designed and fabricated the samples of the gradient index fiber (GIF) lens arrays and single mode (SM) fiber arrays for composing a… more
Abstract:ABSTRACT: Agiltron and the University of WisconsinMadison will develop the first SWIR Image Sensor with a flexible FPA. The sensor is based on the integration of single-crystal Si and Ge nanomembranes, which has the potential to achieve defect-free Ge-based photodiodes for SWIR imaging while… more
Abstract:DESCRIPTION (provided by applicant): Intraoperative imaging techniques are used by neurosurgeons in the treatment for primary brain tumors such as gliomas to achieve maximal surgical resection of pathological tissue while leaving essential areas intact. Current imaging techniques include magnetic… more
Abstract:The current NASA spacesuit community is focusing on utilizing a 13" hemispherical helmet for the next generation of extravehicular activity spacesuits. This helmet architecture presents the end user with a myriad of positive attributes, including a large field of view, enhanced CO2 washout and… more
Abstract:DESCRIPTION (provided by applicant): For dental and other applications there is a great need for self-filling tissue expanders with the capacity to be reshaped to fit the void by the surgeon at time of implantation. Akina recently completed an initial Phase II study using its hydrogel-based… more
Abstract:DESCRIPTION (provided by applicant): Of all diseases, tuberculosis (TB) represents one of, if not, the greatest health disparity between whites and minorities . For every TB-infected white person in the United States, there are an estimated 9 African- Americans, 8 Latinos, 6 Native Americans, 23… more
Abstract:"Measles is a highly contagious, human disease that is spread by the respiratory route, and, in the developing world, remains a leading cause of death due to vaccine-preventable infectious diseases in children younger than 5 years. The most recent estimates are that there were 139,300 deaths… more
Abstract:In recent years, the need for highly reliable, durable and non-intrusive systems for monitoring the health condition of naval structures becomes more and more recognized. Of particular importance is the condition based maintenance of Navy rotating machinery (motors, generators, pumps, gear systems,… more
Abstract:DESCRIPTION: Lead toxicity is a serious but preventable public health problem in the U.S. and elsewhere in the world. Even at very low levels, ingested lead causes irreversible damage, especially in young children, resulting in decreased IQ, learning disabilities, attention deficit disorders,… more
Abstract:DOEs mission of nuclear material control and accountability (NMC & amp;A) requires adequate tools, therefore, the development of new sensor materials and measurement techniques for NMC & amp;A is important for the future of the U.S. nuclear fuel cycle. These techniques will reduce… more
Abstract:Nuclear power is an important part of the Nations energy security providing 20 percent of U.S. electricity generation without the emission of gases associated with global climate change and air pollution. The DOE would like to improve and optimize the performance of nuclear power plants by improving… more
Abstract:Dry storage systems are designed to safely confine the used nuclear fuel by providing radiation shielding, heat dissipation and protection of fuel assemblies from outside elements. To avoid dry storage system breach due to material deterioration or other factors, sensors can be sealed inside to… more
Abstract:The proliferation of weapons of mass destruction such as nuclear missiles and dirty bombs is a serious threat in the world today. Fast-neutron detectors are an important tool in monitoring the proliferation of nuclear weapons. Discrimination between fast neutrons and gamma rays is typically… more
Abstract:While substantial advancements have been made in realizing tube based large area detectors such as the Large Area Picosecond Photo-Detector (LAPPD), there is widespread agreement in the cathode community that a higher QE bialkali cathode is possible, and that the present understanding is largely… more
Abstract:Realization of high-performance compact lasers will require the development of substrates and advancements in optical coatings that can withstand the harsh environments of corrosive gases, high temperatures, and high energy densities. Toward this end we intend to undertake the development of novel… more
Abstract:The goal of this program is to develop a process for producing ceramic materials with properties approaching or, possibly in some aspects, exceeding those of single crystals. Ceramic processing provides important benefits including lower cost, higher yield, relaxed constraints on size and shape,… more
Abstract:In the event of an intentional or accidental release of ionizing radiation, it will be critical to have rapid triage assessment tools to evaluate the health of mission-critical personnel and to make effective use of available medical and emergency resources. However, assessment of whole body… more
Abstract:Todays conventional solar energy conversion technologies face serious problems, because of their combination of moderate efficiencies and high photovoltaic complexities, and because they are burdened with high manufacturing costs. For solar cells to be cost-competitive with other primary sources of… more
Abstract:An important type of water pipe is the Prestressed Concrete Cylinder Pipe (PCCP). There are thousands of miles of PCCP installed in the US in sections with length up to 20 feet and diameter for 2 to 14 feet. The large size of the pipes, the thickness of the concrete (up to 10 inches) and the… more
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