Abstract:Minimization of blade tip clearance in the high pressure turbine and high pressure compressor is very important for turbine efficiency, reduction of emissions, and lower rotor inlet temperature which extends the service life of the engine. This can result in increased payload, extension of mission… more
Abstract:A number of unique non-destructive testing techniques and fundamental research studies are enabled by the modern bright pulsed neutron sources. In addition to all the methods previously developed at continuous neutron sources the pulsed structure of neutron beam enables a number of novel… more
Abstract:DESCRIPTION (provided by applicant): Paroxysmal Nocturnal Hemoglobinuria (PNH) is an orphan disease characterized by severe anemia, kidney and liver failure, and ultimately death, if left untreated. In 2007, FDA approved the first complement inhibitor, Eculizumab (Soliris(R)), for the treatment of… more
Abstract:DESCRIPTION (provided by applicant): Complement system play a role in preventing inflammation and joint immobility. Osteoarthritis (OA), an inflammatory disease of the joints, is quite prevalent among the elderly and causes disability in nearly 10% of thepopulation over 55 years. Current… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this project is to discover novel antibiotics to combat important drug-resistant pathogens. We are running out of treatment options for pathogens such as S. aureus MRSA, vancomycin-resistant Enterococci (VRE), multidrug-resistant P. aeruginosa… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a new platform technology to exploit previously inaccessible microbial diversity to discover novel broad-spectrum antibiotics. The project focuses on symbioses between marine invertebrates and microorganisms known to be rich… more
Abstract:Detecting light at the single photon level is a fundamental measurement function that is useful in a wide variety of applications, including such diverse fields as quantum communications, laser ranging, and biological spectroscopy. Avalanche photodiode based single-photon detectors are convenient… more
Abstract:U.S. intelligence, reconnaissance, and surveillance (ISR) platforms employ SIGINT sensors for target platform detection, identification and location. Many receivers are narrowband and are scanned over the RF spectrum (e.g., 2-18 GHz) in search of RF emitters of interest. With the rapid proliferation… more
Abstract:Nonlinear manifold learning is an active area of mathematical research. Unfortunately, the extant literature has far less to offer on the problem of interactive nonlinear manifold learning. In other words, satisfactory nonlinear manifold learning approaches that put the''human in the… more
Abstract:A goal of Uncertainty Quantification (UQ) is to use computer simulation of complex systems to make scientifically informed assessments for high-consequence decisions. Because end-to-end empirical data is difficult to obtain for the Ballistic Missile Defense System (BMDS), computer simulation… more
Abstract:The US Navy uses manned and unmanned airborne platforms for ISR missions in challenging littoral environments with non-segregated airspace, restricted operating regions, and sensor occlusions, while tracking and classifying potentially hundreds of targets. In this Phase I effort, we propose to… more
Abstract:Department of Defense (DoD) operations are supported by a global network of computers, sensors, and equipment that is continually at risk of being breached by adversaries. Despite heavy investments in security and cyber defense, the ubiquity and interconnectedness of DoD equipment leave open the… more
Abstract:For Unmanned Aircraft Systems (UAS) to operate seamlessly in both the U.S. National Airspace System (NAS) and abroad, it will be crucial that they possess a sense-and-avoid (SAA) capability that can ensure safe operations among maneuvering, non-cooperative aircraft. Numerica Corporation, in… more
Abstract:Emerging infrared (IR) sensor assets will play a crucial role in creating a robust and flexible Ballistic Missile Defense System (BMDS) because they are more easily deployed in forward-based and/or space-based environments, providing coverage of threats beyond the range of terrestrial sensors, and… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project will develop algorithms and prototype software to track and quantify forces experienced by single-biomolecules in living cells. The approach is built on recent advances in time series analysis to: (1) fit 2-D/3-D stochastic… more
Abstract:ABSTRACT: Current and projected limitations on the maximum power from a high power single mode fiber laser amplifier impose architectural limitations on a high power phased array laser weapon system. Prior studies strongly indicate that when faced with this limitation the optimal approach is (to… more
Abstract:ABSTRACT: Nutronics, Inc. proposes to develop a detailed conceptual design for a general purpose, rugged, compact and lightweight beam director design for high energy laser phased array weapon systems. Our expertise in target based phase measurement approaches provides us with a unique insight… more
Abstract:NxGEN Electronics Inc. (www.NxGENelectronics.com), teamed with its subcontractor Linear Signal, LLC (www.linearsignal.com) has successfully completed a Phase I contract for the 2011 NASA SBIR Phase I, Topic S1.02, subtopic, "Low Cost mm-wave Beamforming MMIC Receiver". These receivers,… more
Abstract:U. S. Navy tactical and strategic forces need a real-time, autonomous classification capability to realize the full potential of fixed acoustic surveillance sensors. In this work, we demonstrate the feasibility of integrating a novel, physics-based automatic classification algorithm into a new,… more
Abstract:The proposed work will address the core physics underlying acoustic reverberation as related to properties of the ocean environment and properties of the acoustic sources, receivers and waveforms that make up ocean-going acoustic systems of interest to the U.S. Navy. Present day active acoustic… more
Abstract:The OASIS/WHOI team will design and develop a long-range under-ice acoustic navigation and telemetry system. The Phase I work has resulted in a much-improved model for under-ice acoustic propagation and an in-depth exploration of the potential for regional scale (200-500 km) acoustic navigation and… more
Abstract:The objective of the proposed effort is to develop and demonstrate a passive hearing protection that affords true sense of presence for normal sound with directionality. Existing hearing protection systems fall short of providing a true sense of situational awareness for the user and are therefore… more
Abstract:The proposed effort is focused on developing a passive field drying system termed as"DrySAF"that will allow marines to dry overnight their clothing system such as boots, uniform, etc. Oceanit will develop a hybrid nanocoposite material that has the capacity to absorb water rapidly from wet… more
Abstract:ABSTRACT: Oceanit will develop a working prototype module that will undergo testing with each category of Threat engagement. We will articulate a clear pathway forward to productization to include package design concepts that meet tactical and environmental considerations. BENEFIT: Dual Use… more
Abstract:Oceanit"s approach is to develop an optically transparent radar absorbing material with super-hydrophobic characteristics comprised of a set of carbon nanotube (CNT) coating layers that adhere to the optical window ports of the imaging system and provide X-band radar protection without… more
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