Abstract:Many military applications require efficient optical sources producing several to hundred watts in continuous-wave (CW) or quasi-continuous-wave (QCW) operation at room temperature (RT) in the MWIR (3-5 micron) and LWIR (8-12 micron) regions. While QCLs have become the sources of choice in these… more
Abstract:DESCRIPTION (provided by applicant): Individuals with intellectual and developmental disabilities (I/DD) have more untreated caries and a higher prevalence of gingivitis and other periodontal diseases than the general population (NIDCR, 2009). In order to address this health care disparity, more… more
Abstract:DESCRIPTION (provided by applicant): We request Phase 1 SBIR funding to develop Set2Read-AK (Alphabet Knowledge), the first component of a larger effort to develop evidence-based, broadly distributable solutions to a widely acknowledged challenge - establishing reading readiness in children with… more
Abstract:Waste-to-energy (WTE) technologies are being developed that combine waste management and energy generation. Theses wastes include a wide range of bio-based fuel stocks (biomass from wood and/or grasslands) or organic waste streams (manure and farm waste, municipal solid waste (MSW), sawdust). Much… more
Abstract:Precision Combustion, Inc. (PCI) will develop a compact, flexible and efficient Battle Fuel Conditioner (BFC) add-on module that will enable a full range of commercial gas cooking appliances to operate normally and reliably using JP-8 or other liquid fuels, LNG or conventional compressed gaseous… more
Abstract:Precision Combustion, Inc. (PCI) is proposing an integrated steam reformer and solid oxide fuel cell design capable of very high efficiency and robust transient operation. By virtue of intimate physical integration, without compromising system complexity, the proposed design enables very high… more
Abstract:ABSTRACT: Precision Combustion, Inc. proposes a novel approach for nanoenergetic particle addition to aerospace fuels using carbon based nano-particles, hence avoiding challenges currently being faced by metal-based particles including particle stability, agglomeration, oxidation, solid combustion… more
Abstract:ABSTRACT: Precision Combustion, Inc. (PCI) proposes to develop a novel, ultra-compact cetane sensor to analyze fuels in real time. The sensor will be capable of determining the cetane number of logistic fuels used for small remote piloted aircraft engines. In Phase I, PCI will perform testing with… more
Abstract:The capability of reforming full-spec JP-8 containing up to 3000 ppmw sulfur in a lightweight and compact package, without any upstream sulfur cleanup, was demonstrated. A new approach, recently developed by PCI was used for sulfur cleanup. Operation of the reformer with multiple fuels including… more
Abstract:A viable JP5/JP8-fueled fuel cell for UAV prime power offers potential for longer mission range and improved efficiency, stealth, performance, and reliability/availability/maintainability. In addition, the flexible electric power generation abilities of the fuel cell offer unique opportunities for… more
Abstract:The U.S. strawberry crop centered on 40,000 acres in California supplies 30% of the worlds strawberries, a marvel of American agricultural productivity. It is also emblematic of fumigation-supported high U.S. agricultural productivity, achieving soil sterilization of soil-borne pests necessary for… more
Abstract:We propose to develop a high throughput in vitro assay to identify genetic factors affecting toxicant impact on neuronal differentiation. This project uses a novel genetic mapping resource developed at Predictive Biology, the Diversity Outbred (DO) Mouse ES Cell Panel. Using robust ES cell… more
Abstract:DESCRIPTION (provided by applicant): Chemokine receptors belong to the most druggable class of receptors and modulate immune responses central to a wide variety of disease states ranging from inflammation and autoimmunity to viral infection, asthma and cancer, making these receptors prime drug… more
Abstract:In ballistic missile defense (BMD), sensor placement and sensor-to-target assignment are daunting tasks; even one missed threat has devastating consequences. The Missile Defense Agency (MDA) seeks innovative algorithms for sensor coordination that recommend placement and response options in… more
Abstract:Army small unit leaders face complex tradeoffs when selecting equipment and routes for a mission. Mnemonics such METT-TC and OAKOC summarize many of the factors that soldiers consider, but quickly and comprehensively analyzing these elements is challenging. Primordial"s flagship product,… more
Abstract:Primorigen Biosciences (R) Abstract Primorigen Biosciences will use SBIR funds to develop a high-throughput toxicology assay system utilizing human ventricular cardiomyocytes (vCMs) differentiated from human induced pluripotent stem cells (hiPSCs). Phase Istudies will convert the small-molecule… more
Abstract:Primorigen Biosciences (R) Abstract Primorigen Biosciences will use SBIR funds to develop a novel commercial assay that measures the toxicity of compounds on human induced pluripotent stem cells (hiPSCs) differentiating into hematopoietic progenitor cells(HPCs) and on HPCs differentiated from hiPSCs… more
Abstract:DESCRIPTION (provided by applicant): Primorigen will use SBIR SHIFT funds to develop an array system that can identify chemically-defined surfaces to optimize induced pluripotent stem cell (hiPSC) differentiation and maturation. The platform initially willbe validated for its capacty to help… more
Abstract:DESCRIPTION (provided by applicant): Primorigen Biosciences (R) Abstract Primorigen Biosciences will use Phase II SBIR funds to advance its novel, 3-dimensional system for robust expansion of induced pluripotent stem cells (iPSCs) by a) scaling up iPSC production in 3L bioreactors, b) validating the… more
Abstract:The Navy is interested in developing high power and high operation efficiency pumps at 808nm for multiple Navy applications. VCSEL technology offers an excellent choice for the development of such laser pumps. Princeton Optronics has developed the technology of high power VCSEL arrays delivering… more
Abstract:Vertical cavity surface emitting lasers (VCSELs) is a new technology which can be used for developing high performance laser components for Atom-based Sensors technology. The narrow linewidth of these devices combined with good polarization extinction ratio and large spacing between the longitudinal… more
Abstract:Megawatt class laser systems using Diode Pumped Alkali Lasers (DPAL) could be possible because of their extremely low quantum defect which minimizes thermal loading and, like other gas lasers, the gain medium can be flowed to reduce thermal management requirements. One key to producing efficient… more
Abstract:We propose to develop an efficient, tunable Q-switched SSL operating at a wavelength of 1651 nm with pulse energy>1 mJ at 2000 Hz repetition rate with in-band laser diode pumping. We will leverage initial work carried out during Phase I of this program to pursue two approaches: (i) a tunable… more
Abstract:Princeton Lightwave proposes to develop a solid state short-wavelength infrared (SWIR) detector technology with true single photon sensitivity and a cutoff wavelength beyond 2.2 um. Both single photon avalanche diodes (SPADs) and negative feedback avalanche diodes (NFADs) will be fabricated. These… more
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