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Displaying 131051 – 131075 of 147094 Awards
Company: Integrated Applied Physics, Agency/Program/Year/Phase: DOE / SBIR / 1990 / 1
Abstract: N/A
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: THIS RESEARCH INVOLVES THE APPLICATION OF IN VITRO DNA AMPLIFICATION AND SPECIFIC OLIGONUCLEOTIDE PROBES TO THE CLINICAL ANALYSIS OF GENETIC DISEASE. THE GOAL OF PHASE I OF THIS PROJECT IS TO SEQUENCE THREE OF THE MORE INFORMATIVE DNA PROBES LINKED TO CYSTIC FIBROSIS. THIS SEQUENCE INFORMATION WILL… more
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE COAGULATION CASCADE CONSISTS OF A NUMBER OF MULTIDOMAIN SERINE PROTEASES AND PROTEIN COFACTORS. AMONG THESE ARE FACTORS IX, X, AND PROTHROMBIN. PROTEIN C DOWNREGULATES THE INTRINSIC COAGULATION PATHWAY BY INACTIVATING FACTORS VAAND VIIIA. FACTORS IX, X, AND PROTEIN C ARE HIGHLY HOMOLOGOUS… more
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE OVERALL GOAL OF THIS STUDY IS TO EVALUATE THE USE OF EMBRYONIC BIOPSY AND POLYMERASE CHAIN REACTION (PCR) AMPLIFICATION TO IDENTIFY MICROINJECTED EMBRYOS IN WHICH THE FOREIGN DNA HAS BEEN INTEGRATED INTO THE GENOME. MICROINJECTED PRONUCLEAR EMBRYOS WILL BE CULTURED TO THE EIGHT-CELL STAGE, AND A… more
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: IT IS THE GOAL OF THIS RESEARCH TO CONSTRUCT A REPRESENTATIVE HUMAN YEAST ARTIFICIAL CHROMOSOME (YAC) LIBRARY FOR SALE TO THE SCIENTIFIC COMMUNITY. THIS LIBRARY WILL BE A VALUABLE RESOURCE FOR LABORATORIES ENGAGED IN HUMAN GENETICS RESEARCH AND THE HUMAN GENOME MAPPING PROJECT. THE SPECIFIC AIMS OF… more
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: IT IS THE LONG-TERM GOAL OF THIS RESEARCH TO DEVELOP A METHOD OF ORDERLY SEGMENTING THE HUMAN GENOME INTO 1-50 MB FRAGMENTS. THIS OBJECTIVE CAN BE ACHIEVED BY STREAMLINING THE SCREENING PROCESS OF HYBRID CLONES GENERATED BY CHROMOSOME FRAGMENT GENE TRANSFER. THE MOST EXPEDITIOUS SCREENING PROCESS IS… more
Company: Integrated Genetics Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE INCIDENCE OF CUTANEOUS MALIGNANT MELANOMA (CMM) IS CURRENTLY INCREASING FASTER THAN THAT OF ANY OTHER CANCER IN THE UNITED STATES. RECENT LINKAGE STUDIES HAVE PROVIDED EVIDENCE THAT A GENE FOR HEREDITARY MELANOMA IS LOCATED ON CHROMOSOME 1P36, SPECIFICALLY BETWEEN THE MARKER LOCI D1S45 AND PND.… more
Company: INTEGRATED LABORATORY SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: N/A
Company: Integrated Learning Systems Agency/Program/Year/Phase: ED / SBIR / 1990 / 2
Abstract: THE PROGRESSIVE SCIENCE INSTRUCTION PACKAGE WILL BE A SOFTWARE AND COURSEWARE PACKAGE WHICH WILL TEACH SCIENCE IN GRADES 6-9 TO STUDENTS WHOSE NATIVE LANGUAGE IS NOT ENGLISH. STUDENTS USING THE PACKAGE WILL LEARN SCIENCE MATERIAL IN MICROCOMPUTER-BASED TUTORIAL DIALOGS THAT INCORPORATE INTERACTIVE… more
Company: Integrated Parallel Technology Agency/Program/Year/Phase: NASA / SBIR / 1990 / 2
Abstract: THE PURPOSE OF THIS PHASE I EFFORT IS TO DEVELOP AND DEMONSTRATE INNOVATIVE HARDWARE TO IMPLEMENT SPECIFIC ROLLBACK AND TIMING FUNCTIONS REQUIRED FOR EFFICIENT QUEUE MANAGEMENT AND PRECISION TIMEKEEPING IN MULTIPROCESSOR DISRETE EVENT SIMULATION. IPT PROPOSES TO BREADBOARD MULTIPLE CUSTOM VME BOARDS… more
Company: Integrated Software Inc Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: THE PROPOSED PROJECT DEFINES METHODS AND TOOLS FOR SPECIFYING TIMING CONSTRAINTS FOR SOFTWARE WRITTEN IN ADA. THE PROJECT WILL ALSO DEFINE COMPANION METHODS AND TOOLS FOR VERIFYING THAT THOSE CONSTRAINTS ARE MET. ISI PROPOSES TO ANALYZE ARMY REQUIREMENTS FOR TIME CONSTRAINED SOFTWARE. RESULTS WILL… more
Company: Integrated Systems I Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: ADVANCED GUN POINTING AND STABILIZATION SYSTEMS FOR BOTH ROTORCRAFT AND FIGHTING VEHICLE BASED WEAPONS REQUIRE THE INTEGRATION OF COMPLEX TARGET LEAD PREDICTION ALGORITHMS, NONLINEAR ADAPTIVE STRATEGIES, AND FAULT-TOLERANT USE OF MULTI-SENSOR SUITES INCLUDING IMV'S, DISTRIBUTED ACCELEROMETERS,… more
Company: Integrated Systems I Agency/Program/Year/Phase: NASA / SBIR / 1990 / 2
Abstract: THE OBJECTIVE OF THE PRESENT PROPOSAL IS THE DEVELOPMENT OF EFFICIENT TECHNIQUES FOR SYSTEM IDENTIFICATION AND ADAPTIVE CONTROL OF LARGE SPACE STRUCTURES (LSS). MANY OF THE ENVISIONED FUTURE SPACE MISSIONS WILL IMPOSE STRINGENT PERFORMANCE DEMANDS ON TRACKING ACCURACY, RESPONSE TIME, ANDACTIVE… more
Company: Integrated Systems I Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: ADDITION OF TVC COULD EASILY DOUBLE THE COST OF SOUNDING ROCKETS UNLESS DESIGN FEATURES THAT LIMIT COST GROWTH ARE INCORPORATED. ALSO, THE DESIGN OF THE TVC SUBSYSTEM MUST BE MODULAR AND SELF-CONTAINED SO THAT THE DEVICE CAN BE CONFIGURED FOR INSTALLATION ON 13 OR MORE SOUNDING ROCKET BOOSTERS.… more
Company: Integrated Systems I Agency/Program/Year/Phase: NASA / SBIR / 1990 / 1
Abstract: MANY ENVISIONED MISSIONS FOR LARGE-SPACE-STRUCTURES (LSS) MUST SATISFY STRINGENT PERFORMANCE DEMANDS, AND HENCE, WILL REQUIRE SOME COMBINATION OF ACTIVE AND PASSIVE CONTROL. IT IS PROPOSED THAT THESE PERFORMANCE REQUIREMENTSMAY BE MORE AFFECTIVELY ACHIEVED BY INTEGRATING THE STRUCTURAL DESIGN WITH… more
Company: Integrated Systems I Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: N/A
Company: INTEGRITY SYSTEMS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THIS INVESTIGATION WILL DEVELOP MULTIPLE MODEL ADAPTIVE ESTIMATION (MMAE) TECHNIQUES FOR DISTRIBUTED KALMAN FILTERS (DKFS), WITH THE GOAL OF IMPROVING FILTER ROBUSTNESS WHILE MAINTAINING NEAR-OPTIMAL ACCURACY OF MULTI-SENSOR NAVIGATION SYSTEMS. THE MMAE APPROACH PROVIDES FILTER ROBUSTNESS IN SYSTEMS… more
Company: Intellicorp Agency/Program/Year/Phase: NASA / SBIR / 1990 / 2
Abstract: ARTIFICIAL INTELLIGENCE TECHNIQUES HAVE BECOME AN IMPORTANT TECHNOLOGY FOR THE SOLUTION OF SOME OF THE MOST DIFFICULT PROGRAMMING TASKS. THE DOMINANT TECHNOLOGY FOR DEVELOPING SUCH APPLICATIONS IS TO WORK IN MULTI-MECHANISM, INTEGRATED KNOWLEDGE-BASED SYSTEM (KBS) DEVELOPMENT ENVIRONMENT, SUCH AS… more
Company: Intellicorp Agency/Program/Year/Phase: DOT / SBIR / 1990 / 1
Abstract: COORDINATING INFORMATION EXCHANGE BETWEEN A LARGE NUMBER OF INTERRELATED RESEARCH AND DEVELOPMENT (R&D) PROJECTS HAS TYPICALLY BEEN CONDUCTED USING HIERARCHICAL DATA BASE MANAGEMENT SOFTWARE FOR CATALOGING AND RETRIEVING PROJECT RECORDS. AN INTELLIGENT R&D INVESTIGATOR'S ASSISTANT, ONE THAT USED… more
Company: Intelligent Automation, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1990 / 1
Abstract: EVEN WITH THE BEST AVAILABLE TELEPRESENCE SYSTEMS, AND THE MOST DEXTROUS MANIPULATORS, IT IS TIME CONSUMING AND UNRELIABLE TO PERFORM FINE MANIPULATION VIA TELEOPERATION BECAUSE OF THE LIMITED TACTILE AND FORCE FEEDBACK. FOR FINE MANIPULATION TASKS, THE GOAL SHOULD BE TO GENERATE RELIABLE, PRESTORED… more
Company: Intelligent Automation, Inc. Agency/Program/Year/Phase: NSF / SBIR / 1990 / 1
Abstract: A SIX LEGGED PARALLEL LINK MANIPULATOR (CALLED A STEWART PLATFORM) HAS THE ABILITY TO PERFORM SIX DEGREE OF FREEDOM MANIPULATION, AND IS MECHANICALLY MUCH SIMPLER THAN CONVENTIONAL SERIAL MECHANISMS WITH SIMILAR MANIPULATIVE CAPABILITY. DESPITE THEIR MECHANICAL SIMPLICITY, SUCH MECHANISMS HAVE NOT… more
Company: Intelligent Automation, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THE PURPOSE OF THE PROJECT IS TO DEVELOP AN ARCHITECTURE AND PROTOTYPE FOR A COMPUTER-BASED TOOL THAT WILL AUTOMATE THE CONVERSION OF PAPER DOCUMENTS (TECHNICAL MANUALS, INCLUDING BOTH TEXT AND GRAPHICS) INTO A FORMAT THAT IS SUITABLE FOR INTERACTIVE ELECTRONIC DISPLAY. OUR PROPOSED FORMAT WILL ALSO… more
Company: Intelligent Automation, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: N/A
Company: Intelligent Micro Systems, Ltd. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: DEVELOPMENT METHODS AND TOOLS ARE NEEDED WHICH BOTH REDUCE DEVELOPMENT COSTS AND FACILITATE COMMUNICATION BETWEEN DEVELOPERS AND MAINTAINERS THROUGHOUT THE LIFE CYCLE. WE PROPOSE TO SCRUTINIZE FUNDAMENTAL ASSUMPTIONS UNDERLYING CURRENT DEVELOPMENT METHODS AND SUPPORTING TOOLS TO DETERMINE THE… more
Displaying 131051 – 131075 of 147094 Awards
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