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Displaying 131701 – 131725 of 145618 Awards
Company: SURMODICS, INC. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: A PROJECT IS PROPOSED TO DEVELOP NEW STABILIZATION TECHNIQUES FOR IMMOBILIZED ENZYMES USED IN BIOREACTORS. THIS TECHNIQUE, WHICH HAS BEEN DEMONSTRATED TO SIGNIFICANTLYSTABILIZE AN ENZYME TO STORAGE AT ELEVATED TEMPERATURES, WILL BE FURTHER DEVELOPED AND APPLIED TO STABILIZATION OF FUNCTIONING… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: COLON CANCER REMAINS A MAJOR MEDICAL CHALLENGE IN TERMS OF INCIDENCE, DETECTION, AND CURE. THE MOST PRESSING ASPECT OFTHE PROBLEM IS THE RELATIVELY HIGH MORTALITY RATE OF 50 PERCENT, DUE PRIMARILY TO THE LATE DETECTION OF THE DISEASE. RESEARCH HAS DETECTED THE PRESENCE OF POTENT MUTAGENS IN FECES,… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: Bio-molecular Technology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE HUMAN HERPES VIRUS TYPE 6 (HHV-6) IS A NOVEL HERPES VIRUS ISOLATED FROM FRESH HUMAN BLOOD MONONUCLEAR CELLS. ALTHOUGH NOT EXCLUSIVELY ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), HHV-6 MAY PLAY A ROLE IN LYMPHOPROLIFERATIVE ABNORMALITIES. AS A RECENT VIRUS ISOLATE, LITTLE IS KNOWN… more
Company: Bio-molecular Technology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE HUMAN HERPES VIRUS TYPE 6 (HHV-6) IS A NOVEL HERPES VIRUS ISOLATED FROM FRESH HUMAN BLOOD MONONUCLEAR CELLS. ALTHOUGH NOT EXCLUSIVELY ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), HHV-6 MAY PLAY A ROLE IN LYMPHOPROLIFERATIVE ABNORMALITIES. AS A RECENT VIRUS ISOLATE, LITTLE IS KNOWN… more
Company: Bio-photonics Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: N/A
Company: Biophotonics Corporation Agency/Program/Year/Phase: DOE / SBIR / 1989 / 1
Abstract: ELECTRONIC IMAGE PROCESSING OF ONE- OR TWO-DIMENSIONAL ELECTROPHORETIC GELS REQUIRES SPECIALIZED SOFTWARE FOR ANALYSIS. ALTHOUGH SEVERAL COMMERCIALLY AVAILABLE PACKAGES PROVIDE GENERIC IMAGE ENHANCEMENT AND SPATIAL ANALYSIS, A HIGH DEGREE OF USER MODIFICATION IS NECESSARY TO PRODUCE USEFUL DATA FOR… more
Company: Biophotonics Corporation Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: BIOPORE, INC. Agency/Program/Year/Phase: USDA / SBIR / 1989 / 2
Abstract: FROZEN POULTRY SEMEN IS NOT USED COMMERCIALLY BECAUSE THE CRYOPROTECTANTS MOST EFFECTIVE FOR SPERM SURVIVAL DURING FREEZING AND THAWING ALSO ARE CONTRACEPTIVE. SERIAL DILUTIONCENTRIFUGATION OR CONVENTIONAL DIALYSIS SUCCESSFULLY REDUCE CRYOPROTECTANT CONCENTRATION, BUT SUCH PROCESSES ARE… more
Company: Bioquant, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: IN THIS PROJECT, THE FEASIBILITY OF A NOVEL, SOLID-PHASE, COLORIMETRIC ASSAY WILL BE INVESTIGATED; MONOCLONAL ANTIBODIES WILL BE COVALENTLY IMMOBILIZED ON GLASS AS THE SOLID MATRIX. SEVERAL CHEMICAL REACTIONS WILL BE STUDIED TO IDENTIFY LINKAGES THAT GIVE LOW NONSPECIFIC BINDING OF PROTEINS AND… more
Company: Bioquant, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: THE LONG-RANGE GOAL OF THIS RESEARCH IS TO DEVELOP A DEVICE INCORPORATING AN ASSAY FOR SIMPLE, QUICK, RELIABLE, ACCURATE, AND HIGHLY SENSITIVE MEASUREMENTS OF COMPOUNDS IN HUMAN SALIVA. PHASE I FEASIBILITY RESEARCH IS FOCUSED ON DEVELOPMENT OF THE SOLID-PHASE ASSAY PORTION WITH PROGESTERONE AS THE… more
Company: Bio-renewables Institute Inc Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: THE CONTROL OF TERMITES IS A MAJOR PROBLEM IN THE UNITED STATES. THE PRINCIPAL METHODS OF WOOD PRESERVATION ARE INORGANIC ARSENIC COMPOUNDS, PENTACHLOROPHENOL AND CREOSOTE. THESE AGENTS APPEAR TO BE ENVIRONMENTALLY HAZARDOUS, INCLUDING CARCINOGENIC. PRELIMINARY RESEARCH HASREVEALED THAT THE… more
Company: Genaissance Pharmaceuticals Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: THIS PROJECT WILL ESTABLISH A SERIES OF PRODUCTS TO FACILITATE THE GENERATION OF HUMAN GENETIC MAPS BY PREPARINGTRANSFORMED LYMPHOCYTES AND EXTENSIVE DATA PROFILES FROM MEMBERS OF ORIENTAL AND CAUCASIAN FAMILIES. THE TEST PANEL WILL BE OF SUFFICIENT SIZE SO THAT RESEARCHERS CAN: (1) DETECT EVEN RARE… more
Company: Genaissance Pharmaceuticals Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THIS PROJECT WILL DEVELOP AN ASSAY TO DETECT INTEGRATED FORMS OF EPSTEIN-BARR VIRUS (EBV) DNA IN THE GENOMES OF CELLS TRANSFORMED BY THIS VIRUS. THE ASSAY WILL UTILIZE SOUTHERN BLOTTING AND POLYMERASE CHAIN REACTION METHODOLOGY TO IDENTIFY THE PRESENCE OF VIRUS-CELL JUNCTION FRAGMENTS INDICATIVE OF… more
Company: SERACARE LIFE SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: A MODEL VACCINE SYSTEM WILL BE DEVELOPED USING RECOMBINANT DNA TECHNOLOGY AND CLASSIC VIROLOGY TO CONSTRUCT A NONDEFECTIVE RECOMBINANT ADENOVIRUS THAT EXPRESSES THE SIMIAN IMMUNODEFICIENCY VIRUS (SIV) ENVELOPE PROTEIN. VACCINATION OF RHESUS MACAQUES WITH THE RECOMBINANT SIV-ADENOVIRUS AND SUBSEQUENT… more
Company: SERACARE LIFE SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: PHASE I RESEARCH IILL DEVELOP A PROTOTYPE ELISA ANTIGEN-CAPTURE KIT TO MEASURE HTLV-I CORE PROTEINS P19 AND P24 PRODUCED DURING VIRUS REPLICATION IN CELLS. HTLV-I IS LINKED TO THE DEVELOPMENT OF ADULT T-CELL LEUKEMIA AND TOTROPICAL SPASTIC PARAPARESIS, A NEUROLOGICAL DISEASE OF INTEREST TO… more
Company: Biospherical Instruments, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1989 / 1
Abstract: THIS PROPOSAL ADDRESSES THE NEED FOR COST EFFECTIVE SURFACE VALIDATION INSTRUMENTATION FOR FUTURE OCEAN COLOR SENSORS, BOTH THE PENDING SEAWIFS SATELLITE, AND THE PLANNED HIGH RESOLUTION SCANNING SENSORS SUCH AS MODIS AND HIRIS. THE SIGNIFICANT INNOVATION PROPOSED COUPLES OPTICAL FIBERS WITH HIGH… more
Company: Biostar Medical Products, Inc Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: BIO-STAR PROPOSES TO DEVELOP A SOLID PHASE ASSAY FOR THE SIMULTANEOUS DETECTION OF THREE OR MORE ANALYTES (ANTIGENS AND/OR ANTIBODIES), USING AN OPTICAL INTERFERENCE SIGNAL. THIS OPTICAL IMMUNOASSAY (OIA) IS A TECHNIQUE FOR THE DIRECT PHYSICAL DETECTION OF THE IMMUNOCHEMICAL REACTION AND GENERALLY… more
Company: Biosym Technologies Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE LONG-TERM OBJECTIVE IS TO APPLY STATE-OF-THE-ART COMPUTER SIMULATION SOFTWARE TECHNIQUES, INCLUDING MOLECULARDYNAMICS, MOLECULAR MECHANICS, AND INTERACTIVE GRAPHICS ANALYSIS, TO THE UNDERSTANDING OF THE CONFORMATIONAL PREFERENCES OF BIOLOGICALLY ACTIVE PEPTIDES TO GUIDE AND STIMULATE THE DESIGN… more
Company: Biosym Technologies Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Displaying 131701 – 131725 of 145618 Awards
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