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Displaying 131876 – 131900 of 145558 Awards
Company: Continental Systems Technology Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: THE ADVENT OF THE SPECIALIZED UNDERGRADUATE PILOT TRAINING SYSTEM (SUPT), AND THE AGE OF THE T-37 AIRCRAFT CURRENTLY USED IN USAF PRIMARY TRAINING, REQUIRE THAT DECISIONS BE MADE WHICH WILL MOVE THE TRAINING INTO THE 21ST CENTURY. THE AIRCRAFT MUST BE PART OF A TOTAL TRAINING SYSTEM THAT WILL… more
Company: Continuum Dynamics, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1989 / 2
Abstract: THE ROTORCRAFT COMMUNITY HAS A CONTINUING NEED FOR IMPROVED DESIGN TECHNIQUES FOR HOVER AND AXIAL FLIGHT. SUCH TECHNIQUES CAN BE EMPLOYED TO BEST ADVANTAGE IF THEY ARE COUPLED WITH NUMERICAL OPTIMIZATION METHODS. THIS COUPLING WOULD MINIMIZE TRIAL AND ERROR COMPUTATIONS WHEN SEARCHING FOR… more
Company: Continuum Dynamics, Inc. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: THE REACTION FORCES REQUIRED TO OVERCOME THE THRUST OF A HANDLINE NOZZLE CREATES TIRING AND UNSAFE CONDITIONS FOR FIRE FIGHTERS, RESTRICTS THEIR ABILITY TO CONTROL THE NOZZLEAND ALSO LIMITS THE PRESSURES AND FLOW RATES WHICH CAN BE USED TO CONTROL A FIRE. IT IS DEMONSTRATED, BASED ON NEWTON'S LAWS… more
Company: Continuum Dynamics, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1989 / 1
Abstract: N/A
Company: Continuum Dynamics, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1989 / 1
Abstract: N/A
Company: Control Techtronics Inc Agency/Program/Year/Phase: DOE / SBIR / 1989 / 1
Abstract: MANY ADVANCES HAVE BEEN MADE IN COAL-WATER SLURRY FUEL (CWSF) BURNERS. THE POTENTIAL BENEFIT OF THIS METHOD OF BURNING COAL IS THAT THE BULK OF THE ASH AND SULFUR ARE REMOVED BEFORE THE COMBUSTION PROCESS, SUBSTANTIALLY REDUCING THE AMOUNT OF SULFUR DIOXIDE PRODUCED. ALSO, BECAUSE LESS EXCESS AIR IS… more
Company: Copley Pharmaceutical Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: PERIODONTAL DISEASE HAS ASSUMED PRIMARY IMPORTANCE AS THE CAUSE OF ADULT TOOTH LOSS. HOWEVER, IT HAS BEEN SHOWN THAT TETRACYCLINE, WHEN PLACED WITHIN A DISEASED PERIODONTAL POCKET, CAN REDUCE POPULATIONS OF THE DISEASE-CAUSING PATHOGENS AND AMELIORATE THE DISEASE. THE PURPOSE OF THIS RESEARCH IS TO… more
Company: COR THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO DEVELOP AN ANTITHROMBOTIC AGENT. THROMBUS FORMATION OCCURS IN ARTERIESWHEN THE GLYCOPROTEIN (GP) IIB-IIIA COMPLEX ON CIRCULATING PLATELETS BECOMES ACTIVATED AND BINDS FIBRINOGEN, CAUSING PLATELETS TO AGGREGATE. PREVIOUS STUDIES CHARACTERIZED THE… more
Company: COR THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: PLATELETS IN CIRCULATION ADHERE TO SITES OF VASCULAR INJURY,BECOME ACTIVATED BY AGONISTS SUCH AS THROMBIN, AND AGGREGATEPRIMARILY BY BINDING. INHIBITORS OF PLATELET AGGREGATION INCLUDE CERTAIN MURINE MONOCLONAL ANTIBODIES DIRECTED AGAINST THE MEMBRANE GLYCOPROTEIN (GP) IIB-IIIA. PLATELET AGGREGATION… more
Company: CORDEC CORP. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: A NEW CLASS OF METAL MATRIX COMPOSITES (MMC'S) BASED ON POLYMERIC REINFORCEMENTS WAS RECENTLY SHOWN TO BE FEASIBLE IN OUR LABORATORIES. PROPERLY DESIGNED, SUCH COMPOSITES WOULD HAVE LOW DENSITY IN ADDITION TO HIGH STRENGTH, TOUGHNESS, AND FATIGUE RESISTANCE. MOREOVER, THE ACOUSTIC DAMPING CAPACITY… more
Company: Corpteks Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: CORTEKS, INC. PROPOSES TO DEVELOP A COMPACT, MODERATELY PRICED, MAGNETIC NEURAL STIMULATOR FOR NEUROPHYSIOLOGY. THEDEVICE WILL OVERCOME SEVERAL LIMITATIONS INHERENT TO ELECTRICAL STIMULATION. BY PERMITTING PAIN-FREE, NONINVASIVE STIMULATION OF DEEP-LYING PERIPHERAL NERVES AND SPINAL ROOTS, AS WELL… more
Company: Corpteks Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: CORTEKS, INC. PROPOSES TO DEVELOP A MICROPROCESSOR-CONTROLLED SELF-OPTIMIZING AMPLIFIER SPECIFICALLY DESIGNED TO RECORD EVOKED POTENTIALS UNDER ADVERSE CONDITIONS. THE DEVICE WILL HAVE VERY HIGH COMMON-MODE-NOISE REJECTION, SUPERIOR ANTI-ALIASING, AND REDUCED SUSCEPTIBILITY TO STIMULUS ARTIFACT… more
Company: Corpteks Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: CORTEKS, INC., PLANS TO DEVELOP AN AUTOMATED, LOW-TO-MODERATE-COST DEVICE FOR CONTINUOUS, REAL-TIME EEG MONITORING. EEG MONITORING IS DESIRABLE IN OPERATING ROOMS AND INTENSIVE CARE UNITS FOR RAPID DETECTION OF CHANGES IN NEUROLOGICAL FUNCTION, THUS PERMITTING IMMEDIATE INTERVENTION. EEG MONITORING… more
Company: Cortest Laboratories Inc Agency/Program/Year/Phase: DOE / SBIR / 1989 / 1
Abstract: THIS STUDY WILL IDENTIFY SEMICONDUCTOR PHOTOANODES AND PHOTOCATHODES THAT OPTIMIZE PHOTO-ELECTROLYSIS OF LIQUID H2S. THE QUANTUM (PHOTOVOLTAIC) EFFICIENCY OF N- AND P-TYPE ELECTRODES WILL BE MEASURED IN A HIGH PRESSURE PHOTOELECTROCHEMICAL CELL. THE GOAL WILL BE TO INCREASE THE YIELD OF HYDROGEN AND… more
Company: Corvas Inc Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: DISSEMINATED INTRAVASCULAR COAGULATION (DIC) IS AN UNDERLYING PTHOGENETIC MECHANISM IN CASES OF VIREMIA (INCLUDING DENGUE HEMMORHAGIC FEVER) AND SEPTICEMIA. THE DEVELOPMENT OF THERAPY AND DECISIVE DIAGNOSTIC TECHNIQUES TO MONITOR THE PROGRESS OF THERAPY ARE IMPORTANT FOR INDIVIDUALS WITH SEPTIC… more
Company: Corvas Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THIS PROJECT WILL DEVELOP MONOCLONAL ANTIBODIES OF THERAPEUTIC UTILITY TO INTERRUPT SEVERE, LIFE-THREATENING THROMBOTIC AND RELATED DISEASES IN WHICH THE ACTIVATION OF THE COAGULATION PROTEASE PATHWAYS PLAYS A SIGNIFICANT PATHOGENETIC ROLE. THE MONOCLONAL ANTIBODIES ARE PREDICTED TO BE OF… more
Company: Corvas Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE OVERALL GOAL OF THIS PROGRAM IS TO DEVELOP CLINICAL IMMUNOASSAYS TO REPORT THROMBOLYTICALLY ACTIVE TPA. TPA COMPLEXED TO THE MAIN PLASMA INHIBITOR (PLASMINOGEN ACTIVATOR INHIBITOR-1 OR PAI-1) WILL NOT BE DETECTED. IN PHASE I, MONOCLONAL ANTIBODIES WITH UNIQUE EPITOPE SPECIFICITY WILL BE… more
Company: Corvas Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE OVERALL OBJECTIVE OF THIS PROJECT IS TO DEVELOP MONOCLONAL ANTIBODIES SPECIFIC FOR ACTIVATED HUMAN PLATELETS. A CENTRAL EVENT IN THROMBOTIC DISEASES IS THE TRANSITION OF CIRCULATING, NONACTIVATED PLATELETS TO A STATEIN WHICH THEY INTERACT WITH ONE ANOTHER TO FORM A THROMBUS. THIS EVENT, PLATELET… more
Company: COVALENT ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: A NEED EXISTS TO DEVELOP ROBUST, ADHESIVE INSULATING COATINGS FOR BIOMEDICAL HARDWARE IMPLANTED IN VIVO. ALTHOUGH MANY ORGANIC POLYMERS HAVE BEEN FOUND TO BE BIO- COMPATIBLE, LONG-TERM ADHESION TO METAL SUBSTRATES HAS YET TO BE ACHIEVED. RESEARCHERS WILL PREPARE NOVEL COMPOSITE FILMS THAT INTERLOCK… more
Company: COVALENT ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: N/A
Company: COVALENT ASSOC., INC. Agency/Program/Year/Phase: DOE / SBIR / 1989 / 1
Abstract: N/A
Company: COVALENT ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: COVALENT ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: N/A
Company: CREATIVE BIOMOLECULES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE GOAL OF THIS RESEARCH IS TO EVALUATE THE ROLE OF METALLOPROTEASE INHIBITORS IN CONTROLLING THE PATHOLOGICAL PROGRESSION OF JOINT DISEASES. IN PHASE I, IT IS PLANNED TOCHARACTERIZE THE ABILITY OF FORMS OF TISSUE INHIBITORS OF METALLOPROTEINASE TO RETARD THE BREAKDOWN OF ARTICULAR CARTILAGE MATRIX… more
Displaying 131876 – 131900 of 145558 Awards
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