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Displaying 141326 – 141350 of 147094 Awards
Company: Biological Research Faculty & Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO ESTABLISH NOVEL RECIPIENT EPITHELIAL CELL SYSTEMS THAT WILL DETECT A WIDE SPECTRUM OF ONCOGENES THROUGH DNA TRANSFECTION. THREE TYPES OF LIVER CELLS REPRESENTING DIFFERENT STAGES OF THE CARCINOGENIC PROCESS WILL BE USED: A NORMAL DIPLOID, AN IMMORTALIZED… more
Company: Biological Research Faculty & Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Biological Research Faculty & Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Biomagnetic Technologies Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Biomed Research Laboratoryt Agency/Program/Year/Phase: USDA / SBIR / 1986 / 2
Abstract: FLEXIBACTER COLUMNARIS IS THE ETIOLOG AGENT OF COLUMNARIS DISEASE. THIS UBIQUITOUS DISEASE HAS SEVERELY IMPACTED THE REARING OF INTENSIVELY CULTIVATED WARM WATER FISH SPECIES SUCH AS CATFISH AND STRIPED BASS. THOUGH THE DISEASE CAN BE TREATED WITH CHEMOTHERAPEAUTIC AGENTS, IMMUNOPROPHYLACTIC MEANS… more
Company: BIOMEDICAL DEVELOPMENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: REMOVAL OF DENTAL CALCULUS REMAINS A MAJOR CONSUMER EXPENSE OF ORAL HEALTH CARE. PRODUCTS DESIGNED TO INHIBIT SUPRA- GINGIVAL CALCULUS FORMATION MAY HAVE ADVERSE EFFECTS ON HOSTMINERAL METABOLISM, AS BIOLOGIC CALCIFICATION OCCURS BY SIMILAR PROCESSES IN ANIMALS AND BACTERIA. DIPHOSPHONATES AND… more
Company: Biomedical Frontiers, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Biomedical Research Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: SCHISTOSOMIASIS, CAUSED BY PARASITIC FLATWORMS LIVING IN THE MESENTERIC/VESICAL VEINS, IS THE SECOND MOST IMPORTANT INFECTIOUS DISEASE OF MAN. PRODUCING CHRONIC ILLNESS, IT SPREADS WITH INCREASING DEMANDS FOR WATER AND INTENSIFIED IRRIGATION IN DEVELOPING COUNTRIES. IT IS A MAJOR CONTRIBU-TOR TO THE… more
Company: Biomedics Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE HARD-COPY FETAL MONITOR RECORD (FMR) PRODUCED AND ANNOTATED DURING LABOR CONTAINS THE HISTORY OF THE LABOR AND IS PART OF THE PATIENTS RECORD. THE BULK AND FORM OF THE FMR IS UNACCEPTABLE FOR THE CHART, THE MEDICAL RECORDS SYSTEM, OR LONG-TERM RETENTION: ALL ARE CRITICAL TO PATIENT MANAGEMENT AS… more
Company: Biomedics Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: CURRENT EXTERNAL FETAL HEART RATE MONITORS PROVIDE VALUABLE INFORMATION. HOWEVER, THEY REQUIRE SKILLED ATTENTION, FREQUENT ADJUSTMENTS, ANDPATIENT RESTRAINT IN ORDER TO OBTAIN CONSISTENT RELIABLE INFORMATION. THIS IS BECAUSE THEDOPPLER SIGNAL CAN ONLY BE CAPTURED FROM A SMALL VOLUME IN THE UTERUS,… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE RAPID INCREASE IN THE NUMBER OF CHLAMYDIAL INFECTIONS AND THE SEVERE COMPLICATIONS ASSOCIATED WITH THIS DISEASE IN HUMANS HAS MADE IT IMPERATIVE TO DETECT THESE AGENTS IN BODY FLUIDS. THE UNIQUE LIFE CYCLE AND CHARACTERISTICS OF THE CHLAMYDIAL AGENTS IN GENERAL PRESENT A SIGNIFICANT HEALTH… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1986 / 2
Abstract: A PROJECT IS PROPOSED TO DEVELOP TECHNIQUES FOR STABILIZATION OF PROTEINS BY COVALENT CROSSLINKING. WE PLAN TO USE MONOCLONAL ANTIBODY SPECIFIC FOR T-2 TOXIN AS THE PRIMARY PROTEIN TO USE FOR DEVELOPING STABILIZATION TECHNOLOGY. USING LIGAND STABILIZATION TO DECREASE INACTIVATION DURING THE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1986 / 2
Abstract: MUCH ATTENTION HAS BEEN FOCUSED UPON THE POSSIBLE USE OF TOXIC BIOLOGICAL AGENTS IN BOTH SOUTHEAST ASIA AND AFGANISTAN. SUCH INCIDENTS INDICATE A NEED FOR IMPROVING THE UNITED STATES CAPABILITY TO ACCURATELY DETECT THESE TOXINS AT LEVELS WELL BELOW THOSE LETHAL TO HUMANS.ONE OF THE MOST COMMON… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: A PROJECT IS PROPOSED TO DEVELOP AN ULTRASENSITIVE ENZYME IMMUNOASSAY FOR SPECIFIC VIRUSES THAT IS EXPECTED TO BE MORE SENSITIVE THAN ANY CURRENTLY EXISTING TECHNOLOGY FOR THAT PURPOSE. THIS PROPOSED ASSAY INVOLVES VIRUS-TRIGGERED RELEASE OF MICROENCAPSULATED ENZYME. THE ASSAY IS NONCOMPETITIVE (I.E… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE CONVENIENCE AND OPTICAL ADVANTAGES OF CONTACT LENSES ARE PRODUCING A GROWING MARKET FOR BOTH THE EXTENDED-WEAR AND DAILY-WEAR PRODUCTS. A NEED REMAINS FOR IMPROVEMENTS IN THE BIOCOMPATIBILITY OF BOTH CONTACT (ESPECIALLY LONG-WEAR) AND INTRAOCULAR LENSES. IN MANY USERS, THE LONG-WEAR CONTACT… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE DEVELOPMENT OF IMMUNOASSAYS FOR SCREENING AND MONITORINGCANCER PATIENTS AND THE PREPARATION OF TARGETED IMMUNOCHEMO-THERAPEUTIC AGENTS HAS BECOME AN INTENSE AREA OF RESEARCH. RAPID ADVANCES IN MONOCLONAL ANTIBODY TECHNOLOGY HAVE MADE POSSIBLE THE DEVELOPMENT OF THESE IMMUNOASSAYS. IT IS ACCEPTED… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE PURPOSE OF THIS RESEARCH IS TO DEVELOP AN ASSAY FOR BORDETELLA PERTUSSIS FROM NASOPHARYNGEAL OR THROAT SWABS TO SCREEN YOUNG CHILDREN WITH SEVERE RESPIRATORY INFECTIONS ANDOLDER CHILDREN AND ADULTS WHO HAVE HAD CONTACT WITH THE DISEASE. ALTHOUGH VACCINES HAVE REDUCED THE NUMBER OF REPORTED CASES… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: TRADITIONAL METHODS OF DIAGNOSIS OF VIRAL INFECTIONS HAVE BEEN PREDOMINANTLY BASED UPON ISOLATION OF VIRUSES FROM INFECTED TISSUES OR EXCRETIONS, PROPAGATION OF THE VIRUSES IN CELL CULTURES, THEN IDENTIFICATION OF THE VIRUS BY DETECTION OF SERUM ANTIBODIES AGAINST THE VIRUS. THESE METHODS OF VIRAL… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THIS PROJECT PROPOSES TO DEVELOP AND DEMONSTRATE THE FEASIBILITY OF AN ENZYME IMMUNOASSAY SUITABLE FOR USE FOR PERSONAL MONITORING OF EXPOSURE TO TOXIC AGENTS. TECHNIQUESARE PROPOSED WHEREBY IT IS ANTICIPATED THAT TOXIC CHEMICALS CAN BE BOUND DIRECTLY FROM THE VAPOR PHASE ONTO SEMIDRY IMMOBILIZED… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: MUCH ATTENTION HAS BEEN FOCUSED ON THE USE OF ILLICIT DRUGS BY PEOPLE FROM ALL FACETS OF LIFE. ONE OF THE MOST POPULAR DRUGS NOW USED IN SOCIETY IS COCAINE. THE DRUG IS BEING USED BY PEOPLE FROM ALL SEGMENTS OF SOCIETY, INCLUDING BLUE-AND WHITE-COLLAR WORKERS, MILITARY PERSONNEL, PROFESSIONAL… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Biomol Research Laboratoryt Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE GOAL OF THIS RESEARCH IS TO DEVELOP A HIGHLY SENSITIVE AND SPECIFIC RADIOIMMUNOASSAY FOR LEUKOTRIENE E4 AND LEUKOTRIENE E4-N-ACETATE, TWO IMPORTANT METABOLITES OF LEUKOTRIENE C4 AND D4. THESE LEUKOTRIENES ARE POTENT BRONCO- AND CORONARY ARTERY VASOCONSTRICTORS, INCREASE VASCULAR PERMEABILITY,… more
Displaying 141326 – 141350 of 147094 Awards
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