Abstract:… are independently predictable, simple to control, and do not show the initial bursts of drug release or terminal drug-dumping characteristic of encapsulating systems. Commercial success will be achieved by a) partnerships where we use our technology for proprietary drugs of … more
Abstract:… in standard stereo displays. In this program HSI will study and design key components of this system. As it evolves this holography development will provide new realism to displays including near to eye, multiuser monitors, and projection displays. BENEFIT: Drug creation,… more
Abstract:…s and detect underwater mines. The maintenance and betterment of health of these dolphins in captivity is a priority in order to improve the fitness and readiness of these animals for defense missions. Accacia International proposes to develop probiotic pharmaceuticals to treat… more
Abstract:Agave BioSystems, with their academic partners at the Mote Marine Laboratory, proposes to develop probiotic pharmaceuticals from indigenous commensal microbes to enhance gastrointestinal health in the bottlenose dolphin (Tursiops truncatus). The dolphin gastrointestinal… more
Abstract:… physics research, nuclear waste cleanup, nuclear treaty verification, geological exploration and development of new sources to effectively address our nations future energy needs. Proposed detectors will also permit scientific research enabling development of new drugs,… more
Abstract:… coatings on aircraft carriers, naval ships, and submarines. In the civilian market, CIMOSA could used to detect oxidative corrosion in coatings on commercial airplanes and automobiles, detection of false coatings on counterfeit electrical components, counterfeit drug… more
Abstract:… in collaboration with the group of Professor Robin Rogers at the University of Alabama, will develop new technology for the acid catalyzed conversion of the plant-derived sugar sorbitol to isosorbide, a diol of interest as a chemical intermediate, pharmaceutical… more
Abstract:… development of the proposed instrument will have wide commercial and scientific applications and benefits. In addition to the Spallation Neutron Source application, the instrument will find applications in oceanographic, biological, chemical, pharmaceutical, energy, and… more
Abstract:…ng and a game changer for automated target recognition". Air Force transition systems include Dismount Detection Radar (DDR) and other next generation Air Force ISR radar systems. Non DoD transitions opportunities exist in border security applications and drug enforcement… more
Abstract:… safe and renewable. Unfortunately, the feedstock sorbitol is produced in too small quantities and at too high of a price to be competitive with petroleum-derived phthalates. As a result of the cost, isosorbide is largely restricted to highly specialized uses in pharmaceuticals… more
Abstract:…, and are well within the technical capabilities of PSI. The proposed structural studies would be of great value in developing a family of HybridCPG products that could dramatically reduce the manufacturing costs of several important classes of advanced … more
Abstract:… potential of this project is the need to replace PEG-based personal care additives, driven by reports that these materials contain toxic side products left after the manufacturing process, such as 1,4-dioxane, among others. The United States Food and Drug… more
Abstract:… and social constraints. BENEFIT: The completion of this project will result in the creation of a secure alert dispatch system for mobile devices that can be used with confidence in adverse communications and hostile environments, including warfighting, peace-keeping, drug… more
Abstract:… systems that will result from this research will help to spread access to clean water. Additional promising applications for the UV light emitting Plasma-shells include sterilization of surface areas, purification of air, medical light therapy, protein analysis, drug… more
Abstract:… ranges in a slim and flat form factor. UV light is an efficient light source for a number of chemical processes and disinfection methods available commercially. It is known to be extremely effective for neutralizing pathogens (bacteria, viruses, cysts) and drugs such… more
Abstract:… simple equipment, is manufacture-friendly, cost-effective, and is available in formats needed for tissue engineering and high-throughput applications. Thus, clinical applications of cell types that were previously considered impossible may be realized, and cell therapy, drug… more
Abstract:…arge volume commodity chemical used in the production of polytetramethylene ether glycol (PTMEG), a component of polyurethane stretch fibers (Spandex) and as an industrial solvent with applications in polyvinyl chloride (PVC) cements, pharmaceuticals and… more
Abstract:…, dengue viruses, and other flaviviruses. In Phase I of this project, we identified several candidate tetrapeptides able to neutralize multiple flaviviruses in in-vitro assays. These very short peptides have a molecular weight below 500, affording them the favorable drug… more
Abstract:… energy source. Commercial Applications and Other Benefits Demand for ammonia in the United States continues to increase. The primary use of ammonia is as a fertilizer; but it is also needed for diverse applications such as com- mercial cleaning products, pharmaceutical… more
Abstract:…cing crystallization. This new application of our entropic bristle technology will allow the three-dimensional structures of proteins to be determined more quickly and reliably. Knowledge of the structures of disease-related proteins is extremely valuable in designing drugs that… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will establish the feasibility of developing a genetically-encoded biosensor to monitor levels of cyclic adenosine monophosphate (cAMP), an important second messenger component of drug signaling pathways. Unlike… more
Abstract:Resodyn Corporation proposes to develop a novel cold chain system with a Lifetime Warranty for the vacuum container. The container composes a passive energy efficient system for transporting blood and pharmaceuticals in hostile environments for up to three days. Capacity is… more
Abstract:… method for IC packages of all shapes and materials that can protect against relabeling, delidding and outright copying. The approach is a novel application of the NanoEncryption platform which has been successfully commercialized for the protection of … more
Abstract:… nanocomposites with ultra-thin (10 100 nm), uniform layers of particles that maintain EMI shielding (up to -100 dB over 4 18 GHz) upon mechanical strains up to 50 % elongation. NanoSonics partner, ILC Dover, is the leading manufacturer of flexible pharmaceutical containment… more
Abstract:…ed OTHR Coordinate Registration accuracy. Improved CR accuracy will enhance the applicability of OTHR as a wide area surveillance asset for Air Force and Homeland Security applications with dramatic cost savings over alternative microwave radar solutions. In the US counter … more
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