Abstract:…ovative 3D printed halofuginone eluding keratin-based wound dressing that could potentially improve healing rates and reduce scarring and contracture in our burned Wounded Warriors. The proposed dressing will be formulated and tested for mechanical properties and drug delivery… more
Abstract:… of interest in a variety of biomedical applications, including several in the fields of oncology and cardiology. While tin-117m can be produced through a variety of methods, there are limiting factors that must be addressed in order to facilitate drug… more
Abstract:… as compared to present techniques. By acquiring data simultaneously at many points, the quality and quantity of data will be improved 100-fold from the current state of the art. These detectors will benefit a wide range of applications ranging from structure-based drug… more
Abstract:… to homeland security, nuclear and high-energy physics research, and the development of new sources to effectively address our nations future energy needs. The proposed detectors will also result in scientific research leading to the development of new drugs,… more
Abstract:… a MS. Mass spectrometry (MS) is one of the most widely used analytical techniques for chemical characterization. It is used routinely in a wide variety of industrial and academic laboratories in a wide set of applications such as polymers, pharmaceutics, life… more
Abstract:This Phase I project will evaluate the feasibility of a pharmaceutical spray quality audit system. The spray quality audit system will estimate the mass distribution of active ingredients and droplet sizes in pharmaceutical sprays using combined fluorescence absorption and light… more
Abstract:… GMTI capability to detect victims in search and rescue operation in cluttered environments such as rough sea and forest. Similarly, law enhancement can use CORSON"s SAR capability to detect persons or facilities hidden under camouflage in border patrol or counter-drug… more
Abstract:… and long term shelf life. Potential markets include first responders, military, medical and
biomedical industry, and agriculture and industrial sectors for clean up and first response remediation. Alternative end user interest might include
clandestine drug synthesis… more
Abstract:… exposure. There are currently no methods of preventing or treating ricin exposure this represents a major unmet need for protection of civilians and warfighters. Because of their excellent safety profile and efficacy, mAbs are a rapidly growing class of therapeutic drugs… more
Abstract:… structures and biological tissue, industrial inspection equipment for product verification and test, laser machining and drilling, microlithography, tissue welding and wideband imaging systems. Potential customers include aerospace, biomedical, pharmaceuticals,… more
Abstract:… to 18T range. NMR spectroscopy is a non- destructive technique for mapping molecular structures and learning how molecules function and relate to each other. This is important for many applications that have benefits to the public including discovering new drugs, evaluating… more
Abstract:… delivery system for topical treatment of peripheral neuropathy (PN), Physical Optics Corporation (POC) proposes to continue development of Nano Therapeutics for Peripheral Neuropathy (NATPEN) in Phase II. The NATPEN includes a nanocarrier (NC) loaded with specific drugs, a… more
Abstract:… devices. Microchip HPLC can and will play an important role in point-of- care measurements, remote sensing and chemical and biological warfare agent detections. Highly parallel configurtaions can enhance the sample throughput considerably with commensurate impact on drug… more
Abstract:Many protein-based drugs have limited efficacy due to a short half-life or require intravenous delivery because of low bioavailability. Extend Biosciences is developing proprietary carrier molecules that allow proteins to access an intrinsic transport pathway for efficient… more
Abstract:… disturb the chemistry of the TNF samples collected. Commercial Applications and Other Benefits: The technology as developed can be extended to many other applications, such as low-level radioactive waste storage, radioactive material transport, chemotherapy-drug… more
Abstract:… have very significant impact on the operating conditions of the next generation nuclear accelerator facilities, that are used not only for scientific research but also for medical and commercial isotope manufacturing. As an example, the radio-pharmaceuticals… more
Abstract:… (PWD) to be applied to severe facial burns, by a medic, at the time and site of injury. The PWD will envelop the head and form an enclosed treatment chamber that will enable immediate topical delivery of high-dose antibiotics, analgesics and anti-inflammatory drugs. Negative… more
Abstract:…. Commercial Applications and Other Benefits: The prototype X-band RF electron source we propose would find immediate application as a tabletop Ultrafast Electron Diffraction (UED) system for time-resolved chemical imaging, and as a resource for the pharmaceutical industry… more
Abstract:…, which requires a safety argument will be simplified through compositional assurance arguments. Numerous safety-critical industries will benefit from formal reasoning and compositional safety arguments, including: - the medical-device industry, for example drug… more
Abstract:…technology will allow the DOE to utilize new detector technology at its synchrotron light source sites which will enable faster X-ray analysis for many diverse fields such as crystallography, catalyst development, forensic sciences, the development of new pharmaceuticals,… more
Abstract:… for wire processing. This will serve as the basis for a pilot operation that will supply 2212 conductor development and production. Applications that benefit from this kind of 2212 conductor include 1) High field MRI machines used widely in medical and pharmaceutical research,… more
Abstract:… overall efficiency of the FAEE production process. Commercial Applications and Other Benefits: In addition to biofuel, the proposed microfluidic automation technology has combinatorial DNA construction and functional screening in these industries: 1) pharmaceuticals,… more
Abstract:…. 2. Quantitative measurement will enhance process control, improve reliability prediction and design validation in semiconductors, photo-voltaic, bio-medical devices and catalysts. 3. Video and dynamic-imaging will advance nano-scale research in pharmaceutical and… more
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