USA flag logo/image

An Official Website of the United States Government

Search

Note: The awards database is continually being updated to reflect accurate data as agencies upload their award information

Download to spreadsheetPrint
Displaying 8451 – 8475 of 9040 Awards
Company: Florida Hospital Assn Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: FLOW, INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: N/A
Company: Focus/Mrl, Inc.-Mrl Pharmaceutical Srvs Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: HIV-1 ENVELOPE GLYCOPROTEINS (GP) ARE VITAL COMPONENTS OF VIRAL PREPARATIONS USED IN SEROLOGICAL ASSAYS. THEY ARE ALSO CRITICAL FOR VIRAL RECOGNITION OF TARGET CELLS. CONSEQUENTLY, PURIFIED VIRUS WITH ENHANCED GP MAY HAVE INCREASED DIAGNOSTIC VALUE. VIRIONS WITH INCREASED GLYCOPROTEIN CONTENT MAY BE… more
Company: Gds Technology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THEOPHYLLINE IS A DRUG CURRENTLY USED BY MOST ASTHMATIC/ALLERGIC ADULTS AND CHILDREN, CONSTITUTING OVER SIX MILLION PATIENTS. THERAPY REQUIRES FREQUENT MONITORING OF THEOPHYLLINE LEVELS IN BLOOD AS IT CAUSES TOXICITY AT CONCENTRATIONS HIGHER THAN 20MG/L AND IS INEFFECTIVE AT… more
Company: GENAERA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE LONG-RANGE OBJECTIVES OF THIS PROJECT ARE TO (1) IDENTIFY NOVEL DRUG CANDIDATES RELATED TO THE MAGAININ CLASSOF PEPTIDES WITH POTENTIAL ANTIBACTERIAL, ANTIVIRAL, AND ANTI-INFLAMMATORY ACTIVITY THAT HAVE GASTROINTESTINAL (GI)-RELATED APPLICATIONS; AND (2) ADVANCE KNOWLEDGE OF… more
Company: Glen Research Corp. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: …, THERE WILL LIKELY BE SIGNIFICANT DELAYS IN ITS COMMERCIAL DEVELOPMENT BECAUSE OF TECHNICAL PROBLEMS IN ITS PRODUCTION ON A LARGE SCALE. THE CURRENT RESEARCH PLAN IS DESIGNED TO LEAD TO THE DEVELOPMENT OF A SYNTHESIS SYSTEM CAPABLE OF BEING ADAPTED TO A PHARMACEUTICAL… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: TAXOL IS A PROMISING NEW ANTICANCER DRUG, ISOLATED FROM THE BARK OF THE WESTERN YEW (TAXUS BREVEFOLIA), AND IS CURRENTLYIN PHASE II CLINICAL TRIALS. DEVELOPMENT OF THIS DRUG IS IMPEDED BY A SUPPLY SHORTAGE. IDENTIFICATION OF NEW TAXOL SOURCES IS HAMPERED BY THE LACK OF SUITABLE… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: CONSIDERABLE INTEREST HAS BEEN FOCUSSED ON THE PRODUCTION AND CHARACTERIZATION OF THERAPEUTIC IMMUNOCONJUGATES. SUCH HYBRID MOLECULES USUALLY CONSIST OF A MONOCLONAL ANTIBODY WITH COVALENTLY ATTACHED TOXIN, DRUG, OR RADIOISOTOPE. SOME OF THESE AGENTS HAVE BEEN SHOWN TO BE… more
Company: Healthtech Services Corp Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: …, UNDER A VARIETY OF MEDICAL REGIMENS. AS ARESULT, CAREGIVER BURDEN IS REDUCED. A VARIETY OF EXISTING TECHNOLOGIES HAVE BEEN INTEGRATED INTO A PROTOTYPE DEVICE WHICH COMBINES SEVERAL OF THE MOST IMPORTANT SELF-CARE ASPECTS INCLUDING: VITAL SIGNS MONITORING, DRUG DISPENSING,… more
Company: Horizons Technology, Inc. Agency/Program/Year/Phase: ED / SBIR / 1991 / 2
Abstract: THE PROBLEM OF EDUCATING TEACHERS, PARENTS AND STUDENTS ON THE DANGERS OF DRUG ABUSE IS AN ENDURING ONE. PRINTED MATERIAL IS READILY AVAILABLE BUT IS INEFFECTIVE IF THE INFORMATION PROVIDED IS TOO CONDENSED AND IS IGNORED IF TOO DETAILED. A COMPUTERIZED VERSION OF SUCH MATERIAL… more
Company: Houston Biotechnology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: …, AND AS AN ASSAY TO SCREEN FOR THERAPEUTIC AGENTS THAT CAN PREVENT NEURAL DEGENERATION. THIS ANTIBODY WILL ENABLE THE QUANTITATION AND HELP DEFINE THE BIOLOGY OF A NOVEL INTRACELLULAR MEDIATOR (DCYT) IN THE NERVOUS SYSTEM, AND COULD LEAD TO THEDEVELOPMENT OF DRUGS THAT… more
Company: Houston Biotechnology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: FILTERING SURGERY, WHEN SUCCESSFUL, IS AN EFFECTIVE METHOD TO REDUCE INTRAOCULAR PRESSURE AND VISUAL FIELD LOSS IN GLAUCOMA PATIENTS. THE CREATION OF A SURGICAL FILTER IN THESE PATIENTS PROVIDES AN ARTIFICIAL ROUTE FOR AQUEOUS DRAINAGE THAT BYPASS THE TRABECULAR MESHWORK. HOWEVER, THIS PROCEDURE IS… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: HIV INFECTION IS CHARACTERIZED BY A LONG ASYMPTOMATIC STATE DURING WHICH THE IMMUNE STATE OF THE INFECTED INDIVIDUAL IS NOT CLINICALLY IMPAIRED. DURING THIS TIME, NEUTRALIZING ANTIBODIES MAY PLAY AN IMPORTANT ROLE IN CONTROLLING VIRUS REPLICATION AND THEREBY MAINTAINING THE DISEASE-FREE STATE. THE… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE LONG-TERM OBJECTIVE OF THIS PROGRAM IS TO DEVELOP NOVEL CANCER IMMUNOTHERAPIES BASED UPON THE ABILITY OF ANTI-T CELL RECEPTOR (TCR) MONOCLONAL ANTIBODIES (MOABS) TO STIMULATE IMMUNE RESPONSES. SPECIFICALLY, WE PLAN TO GENERATE ANTI-CLONOTYPIC AND ANTI-TCR MOABS TO T CELL CLONES CYTOTOXIC FOR… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: ANTIBODIES CAN BE FOUND IN THE SERA OF HIV SEROPOSITIVPARTICULAR, ANTIBODIES ARE PRESENT WHICH ARE REACTIVE AGAINST VARIOUS EPITOPES OF THE HIV ENVELOPE PROTEIN GP120. MANY OF THESE ARE STRAIN SPECIFIC AND REACT WITH HYPERVARIABLE DOMAINS, WHILE OTHERS, PRESENT AT LOWER LEVELS, ARE DIRECTED AGAINST… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: SLE IS AN AUTOIMMUNE DISEASE OF UNKNOWN ETIOLOGY WHICH AFFLICTS, PRIMARILY, WOMEN OF CHILD-BEARING AGE. PRODUCTION OF AUTOANTIBODIES, PARTICULARLY THOSE SPECIFIC FOR DNA AND OTHER POLYNUCLEOTIDES ARE CENTRAL TO THE PATHOGENESIS OF THE DISEASE. THE OVERALL OBJECTIVE IS TO REGULATE AUTOANTIBODY… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: In Vitro Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: …BE USED (Q LIVER S9 AS A METABOLISM SYSTEM) AS MODEL COMPOUNDS WHICH SHOULD DISCRIMINATELY EFFECT THIS NEPHROTOXICITY BATTERY. IN VITRO TECHNOLOGIES CAPABLE OF PREDICTING TOXIC MECHANISMS WOULD MARKEDLY ACCELERATE THE PRODUCT DEVELOPMENT PROCESS IN THE PHARMACEUTICAL INDUSTRY… more
Company: LAKE PHARMACEUTICAL Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: INTEGRATED LABORATORY SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: … RESEARCH BY GOVERNMENT AGENCIES AND THE PRIVATE SECTOR. AWARDEE'S STATEMENT OF THE POTENTIAL COMMERCIAL APPLICATIONSOF THE RESEARCH: WHEN DEVELOPED, THE SINGLE CELL GEL ASSAY WILL BE USED BY PRIVATE INDUSTRY FOR THE TESTING OF GERM CELL ACTIVITY IN PHARMACEUTICALS AND CHEMICALS… more
Company: Interneuron Pharmaceuticals Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: … AGENTS, HAVE PRODUCED UNTOWARD CARDIOVASCULAR AND BEHAVIORAL EFFECTS AS A CONSEQUENCE OF THE DOSES REQUIRED TOSIGNIFICANTLY AFFECT FOOD INTAKE. LONG-TERM THERAPY WITH SOME OF THESE AGENTS HAS RESULTED IN THE DEVELOPMENT OF TOLERANCE, NECESSITATING THE NEED TO INCREASE DRUG… more
Company: INTERSYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THIS STUDY WILL DEVELOP AND PILOT TEST AN ASSESSMENT SCALE TO MEASURE DRUG ABUSE RISK AMONG AMERICAN WORKERS WITHIN EMPLOYEE ASSISTANCE PROGRAM (EAP) AND WORKPLACE SETTINGS. THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO PRODUCE A RELIABLE, VALID, AND USEFUL MEASURE OF DRUG… more
Company: JACOBUS PHARMACEUTICAL COMPANY, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE RESEARCH IS DESIGNED TO DEVELOP AN IMPROVED SYNTHETIC METHOD FOR THE PRODUCTION OF A NEW BIOEFFICIENT DERIVATIVE OF AN ORALLY ACTIVE IRON CHELATOR FOR THE TREATMENT OF IRON OVERLOAD. IN PHASE I HUMAN TRIALS, THE PARENT DRUG (GIVEN ORALLY IN CAPSULES) PRODUCED AN AMOUNT OF… more
Company: Kdc/isi Joint Venture Agency/Program/Year/Phase: USDA / SBIR / 1991 / 2
Abstract: … IN GRAINS FLOWING IN A CHUTEOR ON A CONVEYOR BELT, OR CONTAINED IN STORAGE OR TRANSPORT BINS. COMMERCIAL APPLICATIONS EXTEND TO OTHER FOOD PRODUCTSAND BYPRODUCTS, AND TO OTHER DIVERSE INDUSTRIES (E.G., FREEZE DRIED FOODS, CEREALS, SUGAR BEET PULP, PHARMACEUTICAL … more
Company: LANDEC CORP. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE MECHANICAL DEVELOPMENT OF A NOVEL, PULSED TRANSDERMAL THERAPEUTIC SYSTEM (TTS) IS DESCRIBED. THE PROTOTYPE TTS USES A MEMBRANE PREPARED FROM A UNIQUE POLYMER MATERIAL THAT IS PROPRIETARY TO LANDEC CORPORATION. THESE MEMBRANES HAVE A VERY LOW DRUG PERMEABILITY BELOW A… more
Displaying 8451 – 8475 of 9040 Awards
Narrow Your Search
By Agency
By Year
By Phase
By Program
By State
By Company Ownership
By Company
HELP FOR NARROW YOUR SEARCH

Search Options

There are several categories such as “By Agency”, “By Year”, “By State” etc. Select a checkbox within a category to refine your search results.

Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.


Search for Either Criteria

When you select multiple values within a category, the results will include values that match either of the selections. For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.


Narrowing the Search Results

You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories. For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.