Abstract:…sed on the repetitive Q-switching of a Nd:YAG laser which meets the requirements of the AFRL. Proof of principle experiments will be performed during this program and analysis will be conducted for the application of the device to high speed imaging. A Phase II contract award… more
Abstract:… are a combination of software and equipment used to customize substrates to specific circuit designs. This collection of equipment and software is known as the programming station and currently occupies two full laboratory benches.With research funds from a Phase I award,… more
Abstract:… recently invented at Iowa State University, to achieve sub-diffraction optical resolution for studies of living cells. The longer term objective (Phases I and II) is to develop an integrated near-field confocal microscope for biological applications. $ = TOTAL AWARD AMTS & NOT… more
Abstract:…o integrate the use of this high-loading support in solid phase synthesis with automated liquid handling into one automated system to produce a library composed of a series of acridine and pyridine based heterocyclic compounds for general screening. $ = TOTAL AWARD AMTS & NOT… more
Abstract:… these chemicals on CNS cultures to monitor the toxicity that may be encountered through environmental exposure. The overall goal is to produce the assays and a set of standardized kits for the agrochemical products discovery, as well as neurotoxicity testing. $ = TOTAL … more
Abstract:… between Anatomix and Chanime will ensure high product quality in all scientific, pedagogical, artistic and commercial aspects. If successful, the novel approach proposed here can be applied to a variety of commercial instructional applications. $ = TOTAL AWARD AMTS &… more
Abstract:…nch and clinical tests in general and chest radiography. Commercialization of the superior anti-scatter grids will occur in Phase III. These new anti-scatter grids could markedly improve screen-film radiography and will also play a role in digital radiography. $ = TOTAL AWARD… more
Abstract:… using context information to predict words and phrases based as text is entered. In addition to context, language structure, and recency and frequency of word usage will also be used to improve predictive capability and increase the rate of text entry. $ = TOTAL AWARD AMTS… more
Abstract:… in their work environments. The final product is intended to prevent accidents caused by individuals whose occupations require sustained periods of vigilance (e.g. pilots, truck drivers etc.) and to assist those suffering from sleep disorders. $ = TOTAL AWARD AMTS &… more
Abstract:… as part of functional cochlear implant systems. The goal of this research is a substantial improvement in the quality of sound provided by cochlear implants, permitting an even higher percentage of recipients to function normally in hearing society. $ = TOTAL AWARD AMTS &… more
Abstract:…e rate at which they are removed or destroyed by the immune system. Much of the work proposed is aimed at obtaining precise information about the behavior of small model compounds which mimic the polyethylene glycol substituents intended for ultimate use. $ = TOTAL AWARD AMTS &… more
Abstract:… on this technology. The reduced number of keys makes it possible to design a highly effective system that is smaller, lighter, and more cost- effective than today's systems, and which is also easier to learn for individuals with basic literacy. $ = TOTAL AWARD AMTS & NOT… more
Abstract:… kinase specificity will be evaluated for their cytotoxic/cytostatic potential, and their effect on cell cycle distribution. More advanced biochemical evaluation and in vivo studies of the drug candidates will be included in Phase II of this program. $ = TOTAL AWARD AMTS & NOT… more
Abstract:… probe, and will experimentally determine the improvement in the ability of clinicians to differentiate prostate anatomical structures. Following a successful evaluation in Phase I, they would develop the algorithm for real-time operation in Phase II. $ = TOTAL AWARD… more
Abstract:… the design and analysis of the test and its preliminary feasibility and validation study. Phases II and III work will concentrate on a wide-range validation protocol, together with optimization studies and a construction of a prototype automated instrument. $ = TOTAL AWARD… more
Abstract:… in vitro evaluation of the aerosol properties and the quality of the aerosolized DNA/vector will be done in Phase I. In Phase II, the investigators plan to commence on clinical scale product development and pre clinical studies in a primate model. $ = TOTAL AWARD AMTS &… more
Abstract:… this knowledge to teachers, who, by virtue of their profession, are at the front line of drug abuse. We will do so by engaging teachers at no expense to themselves, in workshop to be conducted by recognized experts from the scientific community. $ = TOTAL AWARD… more
Abstract:… agents will target IGF-I receptor expression through a novel mechanism of action and may be applicable to other forms of cancer. Additional success with the SCRIBE technology will also attract licensing agreements with other pharmaceutical companies. $ = TOTAL AWARD AMTS & NOT… more
Abstract:… numerical methods with highest priorities will be implemented, producing a fully functional program. Creation and usability testing of the interface and rigorous definition of the computational requirements will demonstrate the feasibility of the software. $ = TOTAL AWARD… more
Abstract:… on (i) evaluation of the grids for performance, (iii) evaluation of all the available approaches of making a focused grid and the associated fabrication issues. In Phase II, research will concentrate on the fabrication and testing of the focused grids." $ = TOTAL … more
Abstract:… similar to TV remote controls. A prototype unit will be build in Phase I to demonstrate concepts and to develop consumer attributes through field trials. In Phase II, they will develop miniaturization concepts to make this a practical unit for home use. $ = TOTAL AWARD… more
Abstract:… ceramic package will allow the use of simple cable connectors, even for large arrays. The technology to be developed will ultimately provide the basis for interconnect systems to be used in human experimentation with neuroprosthetic applications. $ = TOTAL AWARD AMTS… more
Abstract:… related cytokines and growth factors. Results obtained from these studies will be valuable for creating long-acting versions of other members of the OH supergene family for use in treating cancer, infectious diseases and hematopoietic disorders. $ = TOTAL AWARD AMTS & NOT… more
Abstract:… accessibility to information? Through answering these six questions, a detailed protocol for the production, testing, and evaluation of an EPSS that enhances adoptive parents' ability to deal with the problems associated with FAS will be developed. $ = TOTAL AWARD AMTS &… more
Abstract:… optimized for operation at 1480 nm. By the use of a fluorescence temperature indicator, conditions for irradiation will be determined (pulse width, power) that give optimal localized ablations with minimum thermal and mechanical shock damage to adjacent regions. $ = TOTAL … more
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