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Displaying 1126 – 1150 of 1244 Awards
Company: Bioquant, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: …eration SalivaSac¿ which permits capture and quantitat(
Company: Dialite Technology Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: … need and a large commercial opportunity. A non-invasive glucose monitor btechnology will be small and inexpensive, since it does not use a detector. Even though recent reseadiabetics are able to forestall the debilitating and often fatal complications of diabetes by frequeonly… more
Company: EDUMEDIA, INC. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: There are more than 8,000,000 diabetics in the United States and 500,000 new cases are diagnosed eaDiabetics are at high risk for serious foot problems due to vascular and neurological deficiencies.injuries occur frequently, and lower extremity amputations… more
Company: EXOCELL, INC. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: N/A
Company: Futrex, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: Blood glucose monitoring is a technique that is widely applied in current diabetes care. It gives testimate of blood glucose upon which changes in their management can be made. The current method, whsource of lancet induced blood sample, is somewhat inconvenient and entails… more
Company: Genetic Models, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 2
Abstract: Our objective is to create a female rat model which exhibits Non-Insulin Dependent Diabetes Mellitus (NIDDM). Literature supports that our diabetic, fatty male rat as superior to other available rat models in the onset and level of diabetes expressed. Characteristics such as… more
Company: OSCIENT PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: We will develop methods that will permit the application of genomic mismatch scanning (GMS) to thegenome. If GMS can be applied to humans, it will rapidly identify the sub-chromosomal locations of cdisorders, such as non-insulin dependent diabetes mellitus, facilitating the… more
Company: Hydronautics Research, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 2
Abstract: … adults, so a quantitative degree of obesity (body fat fraction) may be deduced. Such routine measurements should result in improved weight control programs with consequent reduction in the health risks associated with hypertension, cardio vascular disease, cancer, diabetes, and… more
Company: Macro International, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: Preliminary studies indicate that use of low-dose insulin therapy may prevent the onset of insulin-diabetes mellitus (IDDM) in certain high-risk individuals. This hypothesis is currently being testedmulticenter clinical trial, Diabetes Prevention Trial- 1 (DPT-1). Should the… more
Company: Macro International, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: …velop an interactive, multimedia product that will assist physicianprofessionals in helping appropriately selected patients with IDDM adopt individualized intensive thproduct will provide guidance for achieving, as optimally as possible for a given individual, the trDiabetes… more
Company: Massachusetts Institute Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: We will develop and pilot test an innovative approach to enhancing the dietary knowledge of peopleparticularly those who either have or are at risk for Type II diabetes, the type which affects peoploverweight and accounts for 90% of the 14,000,000 Americans who have diabetes.… more
Company: Minnesota Datametrics Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: …een objects and between points in space and 3D objects. Pimplementation will be tested on two experimental models: 1) spatial relationships between nerve celterminal synaptic fibers; 2) characterization of the 3D branching geometry of sensory and sudomotornormal and diabetic… more
Company: OPTIVA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: …rushing patterns will compliment in vitro studies and lead to theimportant brushing characteristics. This approach to enhancing toothbrush efficacy may provide highoral health for both the general population and those with periodontal disease.National Institute of Diabetes and… more
Company: Raya Systems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: The Diabetes Control and Complications Trial (DCCT) has shown that tight metabolic control can reduterm complications of diabetes. Blood glucose monitoring at home, combined with frequent communicatiinformation to health care providers, can help improve patients' diabetes… more
Company: Reshet, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 2
Abstract: …ifications will involve an external "plug-in" module to avoid damage to the imager and to expedite the animal experiments. This innovation will revolutionize many areas of medical diagnosis. These areas will range from retinal blood flow imaging to characterization of diabetic… more
Company: SABOLICH RESEARCH AND DEVELOPMENT, INC. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: Diabetic patients with peripheral sensory neuropathy are at high risk for the development of foot uulcerations remain unnoticed in the absence of pain or "protective sensation" and often develop intothat can lead to amputation. Fifty to seventy percent of all lower extremity… more
Company: Three-dimensional Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: … is to inhibit the angiogenic process through the specific antagonism of a growth finteraction. Although an absolute requirement for the proper development of a growing fetus, angiogebeen associated with numerous disease states, including the growth of solid tumors, diabetic… more
Company: Triangle Research and Development Corporation Agency/Program/Year/Phase: ED / SBIR / 1995 / 2
Abstract: …AN TO COMPLETE DEVELOPMENT OF THE SYSTEM AND DEMONSTRATE ITS USABILITY AND "USER FRIENDLINESS". A PHASE II APPLICATION IS PLANNED IN WHICH THE PROJECT WILL BE TESTED ON A GROUP OF FORTY PATIENTS WHO HAVE OPTED TO LEARN HOME GLUCOSE MONITORING AND HAVE ENROLLED IN THE DIABETES… more
Company: Variseal Manufacturing Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: … in thehydrocolloid dressings. Current research shows that the presence of such NO releasing polymers in thenhancement of wound repair. Evidence also exists that enhanced NO production, occurring in normal awounding, is suppressed in diabetic or otherwise… more
Company: Vivorx Pharmaceuticals, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: The maintenance of euglycemia should prevent the development of or halt the progression of secondarcomplications of Diabetes Mellitus. Exogenous insulin therapy has been unsuccessful in producing coeuglycemia. Pancreatic tissue replacement has shown encouraging results but is… more
Company: Vivorx Pharmaceuticals, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 1
Abstract: Diabetes affects 11,000 people in America and 60,000 new cases are diagnosed every year. The transpencapsulated, immunoprotected islets as a treatment has recently generated much interest. The minuteof glucose achievable by this technique is not possible by conventional… more
Company: Angel Wings Technology Agency/Program/Year/Phase: HHS / SBIR / 1994 / 2
Abstract: THE GOAL OF THE RESEARCH IS TO GENERATE DIAGNOSTIC REAGENTS AND/OR THERAPEUTIC REAGENTS FOR DIABETES THROUGH PRODUCTION OF MONOCLONAL ANTIBODIES TO THE PEPTIDE HORMONE, AMYLIN. AMYLIN IS A NEWLY DISCOVERED PEPTIDE HORMONE THAT IS ACTIVE IN THE CONTTROL OF GLUCOSE METABOLISM AND… more
Company: Avocet Medical Inc. Agency/Program/Year/Phase: HHS / SBIR / 1994 / 2
Abstract: … WOULD ENABLE SUCH HOME TESTS. IT IS BASED UPON COMBINING THE TECNOLOGY OF OPTICALLY ACTIVE THROMBIN SUBSTRATES WHICH ENABLE SIMPLE PROTHROMBIN TIME TESTS) WITH THE DRY REAGENT TECHNOLOGY COMMONLY USED TO MAKE LOW-COST STRIP/METER-BASED HOME BLOOD GLUCOSE TESTS FOR DIABETICS.… more
Company: Biotronics Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1994 / 1
Abstract: A program for the research/development of a reflective, near infrared glucose analyzer isproposed. The design approach allows for an optical computing approach to signal processing andpattern recognition that has the potential for a compact, low-cost instrument for diabetic… more
Company: Cvi Laser Corp, East Agency/Program/Year/Phase: DOD / SBIR / 1994 / 1
Abstract: … noise ratio, and building a compact prototype with improved electronics. Anticipated Benefits: Non-invasive measurement of blood glucose concentration. Alternative application to non-invasive measurement of other body chemicals. Use for home glucose monitoring in diabetics.… more
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