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Displaying 1226 – 1246 of 1246 Awards
Company: Sphinx Pharmaceuticals Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: …. THE CENTRAL INVOLVEMENT OF PROTEIN KINASE C AND SN-1,2-DIACYLGLYCEROL SECOND MESSENGERS IS RELEVANT TO ENDOCRINOLOGY, NEUROLOGY, GROWTH, DIFFERENTIATION, DEVELOPMENT, ARTHRITIS AND OTHER INFLAMMATORY RESPONSES, SMOOTH MUSCLE CONTRACTION, PSORIASIS, DIABETES, AND OTHER… more
Company: Amnis Corporation Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: … ATTACHMENT TO EXISTING, BULKY INFUSION PUMPS AND IMPROVE THE QUALITY OF LIFE. OTHER APPLICATIONS FOR A WEARABLE INFUSION DEVICE COULD BE FOR ENTERAL FEEDING, CONTINUOUS DRUG INFUSION, CHEMOTHERAPY FOR CANCER PATIENTS AND CONTINUOUS DELIVERY OF INSULIN TO DIABETICS. A SMALL… more
Company: Applied Medical Technology Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: … WITH SMALL ANIMAL STUDIES. ISSUES SUCH AS ENZYME STABILITY, MEMBRANE EXCLUSION PROPERTIES, BONDING, BIOCOMPATIBILITY, RESPONSE TIME, AND LINEARITY WILL BE CHARACTERIZED IN IN VITRO AND IN VIVO MODELS. THIS SENSOR WILL PROVIDE MORE THAN 2 MILLION INSULIN DEPENDENT DIABETICS… more
Company: Giner, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THIS RESEARCH PLAN IS DIRECTED TOWARDS IMPROVING ARTIFICIAL KIDNEY TECHNOLOGY, ONE OF THE SPECIFIC AREAS OF INTEREST TO THE NATIONAL INSTITUTE OF ARTHRITIS, DIABETES, AND DIGESTIVEAND KIDNEY DISEASES. BY THE MIDDLE OF 1977 MORE THAN 36,000PATIENTS WERE BEING REGULARLY TREATED… more
Company: Kensal Consulting Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: RECENT INFORMATION SUGGESTS THAT THE MEXICAN HISPANIC POPU- LATION IN THE UNITED STATES IS AT HIGH RISK FOR CORONARY HEART DISEASE, DIABETES MELLITUS, AND SOME SITE-SPECIFIC FORMS OF CANCER. OTHER DATA INDICATE THAT SOCIOCULTURAL FACTORS MAY PLAY A PRIMARY ROLE IN DETERMINING… more
Company: Medical Diagnostic Tech Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THIS PROJECT WILL DEVELOP A TEST WITH PROSPECTIVE COMMERCIALAPPLICATION TO IDENTIFY PANCREATIC ISLET CELL ANTIBODIES (ICA) WHOSE PRESENCE IN HUMAN SERUM IS INDICATIVE OF PRE- INSULIN-DEPENDENT DIABETES MELLITIS (IDDM) OR ITS VERY EARLYSTAGES. AS NO STANDARDIZED ANTIGEN SOURCE… more
Company: Moleculon Research Corp Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: … REMOVE A MAJOR SOURCE OF DANGEROUS LABORATORY ERROR - MISIDENTIFICATION OF SAMPLES DURING POURING OPERATIONS. ANOTHER ASSOCIATED BENEFIT, REDUCTION IN ANALYTIC TURN-AROUND TIMES, COULD ITSELF BE LIFE-SAVING IN CASES SUCH AS SEVERE ELECTROLYTE IMBALANCE OR DIABETIC COMA… more
Company: O'connor Diagnostics Corp Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: SPECIFIC LONG-TERM OBJECTIVES ARE TO DEVELOP A DIAGNOSTIC TEST THAT WILL DETECT THE OCCURRENCE OF DIABETIC NEPHROPATHYAT AN EARLIER, TREATABLE PHASE. THE DEVELOPED TEST REAGENT WILL BE MONOCLONAL ANTIBODIES TO ANTIGENS THAT ARE ASSOCIA- TED WITH DIABETIC NEPHROPATHY. THE SOURCE… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: … EXAMINE ITS EFFECT ON THE EYEIN VIVO. A PREPRODUCTION TOOL AND ASSOCIATED APPLICATION PROTOCOL WILL BE DEVELOPED AND EXTENSIVELY TESTED IN PHASE II. THE SUCCESSFUL DEVELOPMENT OF THE DEVICE WILL PARTICU- LARLY BENEFIT THOSE WHO SUFFER FROM COMPLICATIONS OF DIABETIC RETINOPATHY… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: … DEVELOPMENT OF IMMUNODIAGNOSTIC TESTS. A CDNA LIBRARY WILL BE CONSTRUCTED FROM HUMAN PANCREAS TISSUE. CLONING WILL BE INTO THE LAMBDA GT11 SYSTEM. CLONES CARRYING ISLET CELL ANTIGEN SEQUENCES WILL BE IDENTIFIED BY DIFFERENTIAL IMMUNOSCREENING WITH SERA FROM TYPE I DIABETES… more
Company: Giner, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 2
Abstract: …VITY AND SELECTIVITY OF A CATALYTIC METAL ELECTRODE FOR DETERMINING GLUCOSE IN BIOLOGICAL FLUIDS. SUCH IMPROVEMENTS COULD LEAD TO THE DEVELOPMENT OF AN IMPLANTABLE GLUCOSE SENSOR THAT COULD PROVIDE OPPORTUNITIES FOR A MUCH GREATER DEGREE OF CONTROL OF GLUCOSE LEVELS IN DIABETICS… more
Company: Iama, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE MECHANISMS OF WOUND HEALING AND TISSUE REPAIR IN HUMANS ARE OFTEN IMPAIRED IN THE ELDERLY, IN CANCER PATIENTS AFTER CHEMOTHERAPY AND RADIATION TREATMENTS, IN PERSONS WITH DIABETES OR POORLY HEALING FISTULAS, GHL-CU (GLYCYL-1-HISTIDYL-1-LYSINE:COPPER(II)) IS A GROWTH FACTOR… more
Company: Kron Research And Consulting C Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: WE PROPOSE TO DEVELOP AND TEST A PORTABLE COMPUTER-BASED DATA COLLECTION/ANALYSIS AND COMPLIANCE ENHANCEMENT SYSTEM FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS (NIDDM). THE DIACARE SYSTEM II WILL CONSIST OF THE DIACARE MONITOR (HARDWARE), WHICH COMBINES COMPUTER… more
Company: Management Tech Consult Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: … MEDICAL INSTITUTIONS WITH A POWERFUL RESEARCH CAPABILITY TO INVESTIGATE HUMAN DISEASE RELATIONSHIPS. NOW CLINICOPATHOLOGIC CORRELATIONS COULD BE ESTABLISHED ON LEADING CAUSES OF MORBIDITY AND MORTALITY ^ CANCER, CEREBRAL AND CARDIOVASCULAR DISEASES, DIABETES MELLITUS,… more
Company: Pharmacy Consultation Services Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Sineograph Corpon Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: …YTHMIA (RSA) WITHIN A SPAN OF 1 MINUTE. USING THIS TECHNOLOGY THE RSA IS INVARIABLY PRESENT AND ACCURATELY QUANTIFIABLE IN ALL INDIVIDUALS REGARDLESS OF AGE. ITS AMPLITUDE FALLS PREDICTABLY APPROXIMATELY 10% PER DECADE. INDIVIDUALS WITH A TRANSPLANTED HEART OR SEVERE DIABETIC… more
Company: Biomedics Inc Agency/Program/Year/Phase: HHS / SBIR / 1984 / 2
Abstract: … DIAGNOSIS, (B) SPINAL CORD INJURY PATIENT MANAGEMENT, (C) POST-ANESTHETIC PATIENT CARE. BECAUSE OF THE PATIENT BENEFITS AND THE EXCELLENT POTENTIAL FOR WIDESPREAD USE, WE THINK THE PROJECT WILL BE OF INTEREST TO THE NATIONAL INSTITUTE OF ARTHRITIS, DIABETES AND KIDNEY… more
Company: Biomedics Inc Agency/Program/Year/Phase: HHS / SBIR / 1984 / 1
Abstract: THE OBJECTIVE IS TO DEMONSTRATE THE FEASIBILITY OF A MEMBRANE-SENSOR SYSTEM SUITABLE FOR USE IN A MINIATURE FIBEROPTIC POTASSIUM-ION SENSOR (OPTRODE) FOR CONTINUOUS MONITORING IN BODY FLUIDS. POTASSIUM LEVELS ARE COMMONLY MONITORED DURING CARDIAC SURGERY, DIABETIC ACIDOSIS,… more
Company: Hybridoma Sciences Inc. Agency/Program/Year/Phase: HHS / SBIR / 1984 / 1
Abstract: THE MEASUREMENT OF GLYCOSYLATED HEMOGLOBIN IS PROBABLY THE BEST MEANS OF ASSESSING GLUCOSE CONTROL OVER TIME IN DIABETICS. IT NOW APPEARS THERE IS INVERSE CORRELATION BETWEEN THE CONTROL OF GLUCOSE METABOLISM AND COMPLICATIONS OF THE DISEASE IN THAT WELL CONTROLLED DIABETICS DO… more
Company: Chesapeake Biological Agency/Program/Year/Phase: HHS / SBIR / 1983 / 1
Abstract: … SUCH AS THAT DETAILED IN THIS PROPOSAL. SINCE HA IS UBIQUITOUS TO MANY TISSUES AND FLUIDS OF PHYSIOLOGICAL ORIGIN SUCH AS CONNECTIVE TISSUE, INTRA- ARTICULAR FLUIDS, AND VITREOUS, THIS PROPOSAL IS RELEVANT TO THE MISSION OF THE NATIONAL INSTITUTE OF ARTHRITIS, DIABETES, AND… more
Company: Genzyme Corp. Agency/Program/Year/Phase: HHS / SBIR / 1983 / 1
Abstract: IN RESPONSE TO THE REQUEST OF THE NATIONAL INSTITUTE OF ARTHRITIS, DIABETES AND DIGESTIVE AND KIDNEY DISEASES FOR RESEARCH INTO THE DIAGNOSIS AND TREATMENT OF "ORPHAN" INHERITED DISEASES AS OUTLINED IN THE OMNIBUS SOLICITATION FOR THE SMALL BUSINESS INNOVATIVE RESEARCH (SBIR)… more
Displaying 1226 – 1246 of 1246 Awards
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