Abstract:… use of Remotely Piloted Vehicle Systems by greatly reducing the search time with the ability to locate missing and/or injured parties via a fly over. Additionally, critical information could be relayed back to first responders and care providers thus saving valuable prep time… more
Abstract:… and accurate for a diverse range of compounds. We discovered that proprietary additives vastly improve extraction of proteins in DBS using electrospray. Our unexpected results appear to dramatically increase analyte recovery concentration while reducing DBS prep, and may… more
Abstract:… in military and commercial markets. The overall program objective is to design a portable, high energy source with fuel flexible capability that reduces the weight burden and improves supply logistics for the dismounted soldier. During the Phase I project InnovaTek… more
Abstract:… facilitate POC analysis, it i critical to integrate sample preparation, sample handling, amplification (PCR; RT-PCR) into a single, automated process. However, few systems have successfully integrated all of these steps. Due to the complexity of integrating sample prep, it has… more
Abstract:… to human volunteers by intradermal (ID), subcutaneous (SC) or intravenous (IV) injection (1). It is highly immunogenic and conferred high level protection (100%) against homologous controlled human malaria infection (CHMI) when administered IV (R. Seder et al., in prep.).… more
Abstract:… sexual health/harm reduction framework, an approach called for by practitioners and public health officials in recent years (Goldhanner and Mayer, 2011; Grossman et al., 2011; Wolitski and Fenton, 2011); a discussion of the pros and cons of pre- exposure prophylaxis (PREP)… more
Abstract:… RNA library. This ligation step can be plagued by the undesired joining of the adapter sequences to one another without a segment of the library in between, resulting in adapter dimer formation. Although affinity capture can be usedto remove adapter dimers in most library … more
Abstract:… the usability of the MESO system. In addition, significantly more testing and validation are necessary to ensure the system performs reliably and up to expectations and to encourage adoption. The two Specific Aims of this Phase II include: 1) optimization of sample prep and… more
Abstract:The technical problem addressed is implementation of a device called the Burn Saver Device (BSD) that can be attached to a firefighter's helmet to
provide an early detection system to warn the firefighter of rapidly developing and/or unsafe thermal conditions in his/her immediate environment… more
Abstract:…anner. A large part of the cost of colonoscopyin the US is ultimately the result of the sedation or anesthesia used to ameliorate the pain and discomfort experienced during insertion of the colonoscope. These results in added overhead costs associated with patient prep and… more
Abstract:…. Pre-enrichment is often used to overcome this limitation, but the significant time advantage of these methods is then lost. Mechanical concentration or enrichment approaches hold promise, but their development has lagged. In an effort to fill this void, InnovaPrep has… more
Abstract:… that are best suited to minimize wall stresses and promote re-endothelialization are least suited to retain intimal flaps and inhibit platelet aggregation. Fortunately, these concerns are most significant along different time frames post-stent deployment. CorInnova is… more
Abstract:… are no practical, integrated systems for assessing biomedical,psychosocial, and behavioral (BPSB) issues--and physicians often lack the time and resources for such total care. SOLUTION: Our goal is to extend an existing online patient (pt) self-assessment system, called Care… more
Abstract:… Science introduceda disruptive product for DNA size selection that electrically switches the desired DNA fragments out of the gel and obviates the need for physically extracting the DNA. Due to its speed and labor saving protocol, the Sage Science Pippin Prep is… more
Abstract:… Compared to cellulose and lignin, hemicelluloses are generally much less stable and are prone to degradation during chemical or thermal treatments. For this reason, hemicellulose is considered an underutilized biomass component in most biomass conversion processes. InnovaTek ,… more
Abstract:… multiplex testing capabilities residing in a single, inexpensive device wil enable near point of care diagnostics for a number of serious infectious agents. The research design for achieving this goal includes four processing elements: 1) A one step sample prep that can be… more
Abstract:…cessing instrument that will purify one milligram or more of plasmid DNA from recombinant culture in 60 minutes.The purification method to be employed in this work is a derivative of proven electrophoretic separation technology that our company developed for automated mini-prep… more
Abstract:…. Large integrated composite structures, low scrap rates, high integrity structural repair, and suitability to the manufacturing shop floor are all primary drivers for this proposed repair technology and will be enabled by our innovative combination of surface prep, repair… more
Abstract:… in multiple ways to effectively address those needs. Instruments that are fast, can work with low sample volumes are typically expensive and have limited sensitivity. Ultra-high sensitivity platforms are also expensive and typically require complex sample prep steps and… more
Abstract:… and detection components requiring
very small volumes, (b) deficiencies in removing inhibitory environmental material and (c) an inability to separate, and thus, differentiate whole
pathogens from exogenous materials derived from those pathogens. InnovaPrep is… more
Abstract:…, CBD is seeking a platform technology for automated, universal sample preparation for biosensor systems using small volumes of samples in complex matrices. To address this need, Physical Optics Corporation (POC) proposes to develop a Universal Bio-sample Preparation (UniBio… more
Abstract:… this prototype detection assay as a launching pad for developing the instrumentation necessary to automate the assay and create a truly field-deployable system. In this proposal, we outline our strategy for this automation. We will (1) automate the sample prep system to… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop high-performance transparent conductors as a replacement to Indium Tin Oxide (ITO) in touchscreens. ITO suffers from a number of disadvantages, including being one of the most expensive components of a touchscreen device… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposal to the U.S. Department of Defense, NAVAIR, Navy, outlines the plan for the qualification of robust, non-delaminating, highly conductive aircraft transparency materials using the Innlay (TM) surface-embedding technology platform… more
Abstract:… to microfluidic sample preparation. A single continuous-flow technology is used to manipulate and separate cells, subcellular organelles, and large genomicDNA molecules (that exhibit particle-like properties). The use of a common technology for all sample prep steps… more
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