Abstract:… to microfluidic sample preparation. A single continuous-flow technology is used to manipulate and separate cells, subcellular organelles, and large genomicDNA molecules (that exhibit particle-like properties). The use of a common technology for all sample prep steps… more
Abstract:DESCRIPTION (provided by applicant): Mortality from colorectal cancer (CRC) can be reduced through screening programs. Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography[virtual colonoscopy]) colonoscopy is… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop efficient manufacturing of nanostructured flexible transparent conducting electrodes (TCEs) with low resistivity and high durability. Flexible nanostructured TCEs will be produced by using the proprietary… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposal to the U.S. Department of Defense (DoD), Navy, requests funding for Innova Dynamics, Inc. to enable innovative manufacturing of robust, non-delaminating, highly conductive aircraft transparency materials… more
Abstract:…ently replacing chrome plating with High Velocity Oxygenated Fuel (HVOF) applied tungsten carbide-cobalt (WC-Co and WC-Co-Cr) coatings. These coatings require diamond wheels for finish grinding the HVOF coatings as well as aluminum oxide grinding wheels for base metal prep and… more
Abstract:… a host of detection moieties (e.g., DNA, RNA, proteins, peptides, whole cells). Ideally, a fieldable bio-sample preparation platform should be rapid, compact, reagent-less, automated, require minimal user training, and universal. We propose to develop a general purpose Bio… more
Abstract:… CPP through apinhole. SOLUTION: Our objective is to develop an assessment for the biomedical, psychosocial, behavioral, and quality-of-life (biopsychosocial, BPS) dimensions of CPP for an existing online, branching, patient self- assessment system called CarePrep, thereby… more
Abstract:… prevalent than preventive care. SOLUTION: Our objective is to deploy a clinical methodology and infrastructure to ensure delivery of patient-centered care to minority and disadvantaged patients. Our work builds on an online, patient self-assessment system called CarePrep, now… more
Abstract:… the chart. If you want to know about AMU, patients must be asked directly; providers will not know and paper questionnaires cannot be scaled into an effective solution. SOLUTION: Our work builds on an operational, Web-based, patient self-assessment system called CarePrep that… more
Abstract:…tended range through integration with a fuel cell that operates on renewable liquid hydrocarbon fuel will meet the needs of airlines and ground handling companies to reduce emissions and fuel costs and provide the convenience of a standard liquid refueling operation. InnovaTek… more
Abstract:A compact and efficient fuel processor that provides clean hydrogen from a high energy density liquid fuel such as butanol will allow fuel cell technology to be realized in military and commercial markets for portable applications. InnovaTek, and its proposal partner Indiana -… more
Abstract:… bacteria fromreal apple juice and spinach wash water into a small volume, which is easily analyzed by advanced detectors, will enable rapid detection of small numbers of bacteria; and, in turn will provide for improved consumer safety and reduced product recalls. InnovaPrep… more
Abstract:… sample preparation and detection components requiring very small volumes, (b)
deficiencies in removing inhibitory environmental material and (c) an inability to separate, and thus, differentiate whole pathogens
from exogenous materials derived from those pathogens. InnovaPrep… more
Abstract:….S. Army"s need for a technology platform for automated, universal sample preparation for biosensor systems using small volumes of samples from complex matrices, Physical Optics Corporation (POC) proposes to develop a universal bio-sample preparation (UniBioPrep) technology… more
Abstract:CustomArray produces a field-deployable electrochemical microarray platform that is ideally suited to the multiplexed detection of pathogenic organisms. In this proposal, we will build a complete detection process that will include: Probe design, sample prep, multiplexed PCR… more
Abstract:… and tick-borne pathogens. The challenge of this task is in the development and validation of HyBeacons probe assays, the validation of the Evogen ONE nucleic acid extraction chemistry, the sequential automation of the pathogen analysis via the automated sample prep (ASP), and… more
Abstract:This SBIR Phase II proposal to the Department of Defense, Army, requests funding for Innova Dynamics to optimize and scale up the Innlay-based IonArmour Next Generation technology for deployment, providing the highest levels of safe, cost-effective, continuous antimicrobial… more
Abstract:… liquid chromatography and capi
llary electrophoresis systems. These tools, however, are typically limited to core facilities at major research centers away from the bench top or the daily workspace of the average biomedical scientist. Laboratory separation and sample- prep… more
Abstract:Repair cycle time reduction is the most significant factor in this effort. Material development and all material candidates will be evaluated for cure and set times, post cure time conditions, material prep and handling time. The technical objectives are to develop concepts… more
Abstract:This SBIR Phase I proposal to the Department of Defense, Army, requests funding for Innova Materials to demonstrate the feasibility of a technology for providing the highest levels of safe, cost-effective, continuous antimicrobial protection for products and materials. The… more
Abstract:… concentrator with proven sample preparation methods and quantitative polymerase chain reaction (qPCR) to provide a detection system for pathogens in drinking water of unparalleled speed, reliability, and significantly lower detection limits.
The InnovaPrep hydrosol… more
ption weight-loss therapeutic is estimated at 18 billion annually. Halsa has assembled a world-class team with exact domain expertise in pharmaceutical drug development. This project will lay the foundation for ZAG to enter full preclinical trials in … more
Abstract:The Air Force is currently replacing chrome plating with High Velocity Oxygenated Fuel (HVOF) applied tungsten carbide-cobalt (WC-Co and WC-Co-Cr) coatings. These coatings require diamond wheels for finish grinding as well as aluminum oxide grinding wheels for base metal prep… more
Abstract:The objective of this project is the design, fabrication, testing and evaluation of an affordable, efficient greywater recycling system for Army mobile field kitchens/sanitation centers. The proposed system utilizes enabling technology, a medialess continuously self-cleaning rotary disk clarifier… more
Abstract:… PM removal efficiencies of more than 99 percent, significantly better than current technologies (sub-scale VOC removal efficiencies were approximately 42% via evaporative cooling, resulting in more than 70% reduction in total grease emissions).
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