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Displaying 676 – 700 of 744 Awards
Company: AEGEN BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant): Accurate prediction of human responsiveness to chemical exposure is difficult, often unreliable, and invariably expensive. Thus, Aegen Biosciences is developing a microfluidic biochip device called… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2001 / 1
Abstract: … similar to DNA chips for multianalyte detection. The combination of the phage array approach with OLED detectionallows development of a powerful biosensing system that does not require additional labeling, sample manipulation, or sophisticated microfluidic and pumping… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 2
Abstract: … (poly-dimethylsiloxane). We demonstrated thefeasibility of our detection platform by developing a highly sensitive, low-cost prototype system, which consisted of an LED excitation source, an optical fiber, two plastic colored filters, the PDMS-based microfluidics, and the… more
Company: Arete Associates Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: …J's. Some optical computingarchitectures propose communications between processors by transitioning from a polymer waveguide to a free-space switch to enable inter-processor communications. Significant signal losses result from this approach. Aret¿'s Micro-Fluidic Actuator… more
Company: CALIBRANT BIOSYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: …batim from the Applicant's Abstract): This proposal describes a research and development plan for novel flow control technology for the manipulation of biological fluids at the micro- and nano-scales. The technology is based on new call microfluidic… more
Company: CALIBRANT BIOSYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: … intensive and time-consuming tasks, prone to poor reproducibility and quantitative accuracy. To increase throughput and decrease cost, automation and miniaturization are beneficial strategies. The specific aims of our proposed research are to (i) develop a 2-D microfluidic… more
Company: CIENCIA, INC. Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: … plasmon resonance imaging spectrometer system for label-free protein expression profiling in space. The system will consist of a rugged, compact instrument with low mass and low power consumption, and a proteomics biosensor chip array integrated into a microfluidics… more
Company: Eltron Research & Development, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: …ally reduce the environmental impact of this manufacturing process. On-line monitoring of key contaminants in real time is necessary to successfully operate future water systems having recycle and reuse capabilities. Phase I research will be directed at developing microfluidic… more
Company: Eltron Research & Development, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2001 / 1
Abstract: … voltammetric method. This method will allow for the analysis of water samples without significant dilution or reduction in the sensitivity of detection. These miniaturized devices will employ a microfabricated, electrochemical detector integrated into a microfluidic flow… more
Company: Eltron Research & Development, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project will develop a small, portable, low-power amperometric biosensor to detect phenol in wastewater. A renewable, robust biosensor integrated into a microfluidic system is proposed and will be designed to specifically… more
Company: GENOME DATA SYSTEMS, INC. Agency/Program/Year/Phase: DOE / SBIR / 2001 / 1
Abstract: …, the complex microfludic chips will not need to be thrown away after use, resulting in much lower analysis cost. Phase I will demonstrate the feasibility of fabricating high-density protein microarrays. In addition, customization of generic microfluidic chips will… more
Company: IA, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2001 / 2
Abstract: … (uranium, strontium, thorium, lead, and cesium) and optimized them for maximal sensitivity to each ion. Selectivity was determined by flow injection analysis and tested spiked samples of groundwater. In Phase II, the array will be integrated with microfluidics,… more
Company: IA, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2001 / 1
Abstract: … (uranium, strontium, thorium, lead, and cesium) and optimized them for maximal sensitivity to each ion. Selectivity was determined by flow injection analysis and tested spiked samples of groundwater. In Phase II, the array will be integrated with microfluidics,… more
Company: Intelligent Optical Systems, Inc. Agency/Program/Year/Phase: DOE / STTR / 2001 / 1
Abstract: The development of microfluidics devices for use in micro-fabricated chemical sensors would improve the capability for detecting weapons of mass destruction. Although a myriad of microfluidics transport devices have been demonstrated, full commercialization has not yet been… more
Company: International Mezzo Technologies, Inc Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project seeks to develop commercially viable methods for the fabrication of high aspect ratio micro- and nano-structures for microfluidic applications using contact nano-printing. X-ray lithography will be used to produce… more
Company: IQUUM, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: … closed tubule polymerase chain reaction (ct-PCR) module, which uses a closed reaction tubule that fits into a portable, hand held thermal cycling device. The ct-PCR module incorporates tubule flow-chamber technology (TFT), a micro-fluid… more
Company: Li-cor Biosciences Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: …f dNTPs labeled on the g-phosphate with fluorescent dyes. The label is cleaved from the nucleotide along with pyrophosphate when the nucleotide is incorporated into DNA by a polymerase. The released label is sorted from intact g-dNTPs in a microfluidics … more
Company: Li-cor Biosciences Agency/Program/Year/Phase: HHS / SBIR / 2001 / 2
Abstract: …f dNTPs labeled on the g-phosphate with fluorescent dyes. The label is cleaved from the nucleotide along with pyrophosphate when the nucleotide is incorporated into DNA by a polymerase. The released label is sorted from intact g-dNTPs in a microfluidics … more
Company: LOS GATOS RESEARCH Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: Los Gatos Research proposes to develop wafer-based microfluidic manifold that includes the micropump and microvalve devices for lab-on-a-chip (LOC) applications. These microfluidic devices will be engineered for integration with chemical and biological LOC detector systems. For… more
Company: LOS GATOS RESEARCH Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: This Small Business Innovation Research Phase I project seeks to develop a low cost, disposable microfluidic manifold that includes a micropump for lab-on-a-chip (LOC) applications. The microfluidic devices will be engineered for integration with disposable… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2001 / 1
Abstract: … by nonspecific fluorescence by other organisms and chlorine compounds present in the sample. The proposed new method is based on two innovations, one which utilizes (di)electrophoretic separation, concentration, and focusing of Cryptosporidium oocysts in a microfluidic sensor,… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2001 / 2
Abstract: … by nonspecific fluorescence by other organisms and chlorine compounds present in the sample. The proposed new method is based on two innovations, one which utilizes (di)electrophoretic separation, concentration, and focusing of Cryptosporidium oocysts in a microfluidic sensor,… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: … binding. The proposed method isbased on electrophoretically separating and directing a single DNA/RNA molecule fragment of interest through a simple, self-assembled nano-pore detector. Sample preparation and detection are performed on-chip using microfluidic principles,… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2001 / 1
Abstract: 60583 A recent advance in high-throughput genomic technologies has led to the development of methods for whole-genome sequencing and for the establishment of comprehensive mRNA expression maps. However, no equivalent technology is currently available for the rapid analysis of proteins and/or… more
Company: Lynntech, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2001 / 2
Abstract: 60583 A recent advance in high-throughput genomic technologies has led to the development of methods for whole-genome sequencing and for the establishment of comprehensive mRNA expression maps. However, no equivalent technology is currently available for the rapid analysis of proteins and/or… more
Displaying 676 – 700 of 744 Awards
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