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Displaying 676 – 697 of 697 Awards
Company: SCRIPTGEN PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1999 / 1
Abstract: …artridge that solves many of the fluidic interconnection problems and biological warfare (BW) instrument contamination concerns. BENEFITS: MesoSystems will drive the standardization of the interfaces because of: Micromachining experience Collector miniaturization Microfluidic… more
Company: PATTON TECHNOLOGY CO. Agency/Program/Year/Phase: DOD / SBIR / 1998 / 2
Abstract: A need exists to develop a fully integrated monolithic microsystem to perform chemical and bloassays in a reliable, accurate and repeatable, even continuous way. Durability of the device is of paramount importance. We propose in Phase I to develop a MEMS microfluidic device… more
Company: Systems & Processes Engineering Corporation Agency/Program/Year/Phase: DOD / SBIR / 1998 / 2
Abstract: … separation steps or sophisticated multiple-fluid injection steps. The proposed system will be implemented into a MEM package which will include a telemetry system for remote deployment applications. The MEM package will include submodules for electronics, microfluidics,… more
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1997 / 2
Abstract: The objective of the project is to develop, validate and demonstrate a simulation tool for the design of microfluidic systems in biological Micro-Electro-Mechanical System (MEMS) devices. The Phase I work will develop models for the flow of biological fluids in components (such… more
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1997 / 2
Abstract: … for modeling the transport and fluid flow phenomena associated with MEMS devices utilize very basic fluid dynamics principles or rely on the semi-empirical correlations. Higher fidelity analysis techniques, such as Computational Fluid Dynamics (CFD), for microfluid design… more
Company: PATTON TECHNOLOGY CO. Agency/Program/Year/Phase: DOD / SBIR / 1997 / 1
Abstract: A need exists to develop a fully integrated monolithic microsystem to perform chemical and bloassays in a reliable, accurate and repeatable, even continuous way. Durability of the device is of paramount importance. We propose in Phase I to develop a MEMS microfluidic device… more
Company: Smart Instruments Agency/Program/Year/Phase: DOD / SBIR / 1997 / 2
Abstract: Application of silicon microfabrication technology to biodiagnostic consumables offers the potential advantages of sub-microliter sample size, immediate test results, and lower cost. Such microelectromechanical systems (MEMS) are limited in achieving their full potential by the present manual… more
Company: Systems & Processes Engineering Corporation Agency/Program/Year/Phase: DOD / SBIR / 1997 / 1
Abstract: … separation steps or sophisticated multiple-fluid injection steps. The proposed system will be implemented into a MEM package which will include a telemetry system for remote deployment applications. The MEM package will include submodules for electronics, microfluidics,… more
Company: Corona Catalysis Corp Agency/Program/Year/Phase: DOD / SBIR / 1997 / 2
Abstract: …, and tested. This device can be coupled with a detection technology for use on the traditional battlefield and in counter-terrorism applications. The aerosol collection system we propose to build uses a combination of microelectromechanical and microfluidic… more
Company: American Research Corporation of Virginia Agency/Program/Year/Phase: DOD / SBIR / 1996 / 1
Abstract: … Systems (uTAS) as well as in both homogenous and heterogeneous immunoassay. However, there remains a need to develop reliable methods of sample introduction to the 150um by 100um sensitive region of the SSDL. This proposal suggests the development of microfluidic… more
Company: EIC LABORATORIES, INC. Agency/Program/Year/Phase: DOD / SBIR / 1996 / 1
Abstract: We propose to develop a generic modular microanalytical system which will integrate sample workup, separation and detection on a chip. It is the ultimate goal to provide chip-based assays dedicated to a predetermined set of analytes. This analyzer will replace more expensive and complex gas… more
Company: Luna Innovations Incorporated Agency/Program/Year/Phase: DOD / SBIR / 1996 / 1
Abstract: …, Inc.) proposes to demonstrate the feasibility of integrating mechanically-active polymer microcomposites with evanescent field grating-based optical sensor elements to store, pump and analyze molecules, agents and toxins in biological fluids. Prototype microfluidic… more
Company: Iep Group, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1996 / 1
Abstract: … medicaments to manage a wide range of disease states including hypertension and diabetes. When coupled with appropriate sensors, this system could also provide means for protection of military personnel against chemical attack. Most implantable microfluidic… more
Company: Smart Instruments Agency/Program/Year/Phase: DOD / SBIR / 1996 / 1
Abstract: N/A
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 2
Abstract: … developed injectable naltrexone microcapsules which produce opioid antagonism for 30 days or more in monkeys. Because the level of residual methylene chloride in those capsules exceeded the chronic exposure limit of the FDA, in this project a new microfluidized bed… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1995 / 2
Abstract: … of an injectable, fully biodegradable microcapsule form of estradiol which delivers 60 micrograms of estradiol per day for 90 days and, thereby, provides estrogen replacement without need for frequent oral or transdermaI administration. A new spray core microfluidized bed… more
Company: SADDLEBACK AEROSPACE Agency/Program/Year/Phase: DOC / SBIR / 1995 / 1
Abstract: … subsystem will be the focus of the Phase I effort, although sizing studies will be performed for the detector and power/electronics subsystems as well. The consideration of the flow subsystem includes the definition of the micro-pump(s), the micro-valves, and the micro-fluidic… more
Company: Sparta Pharmaceuticals Corp Agency/Program/Year/Phase: HHS / SBIR / 1994 / 1
Abstract: … formulationwith increased bioavailability and a slow-release formulation for intramuscular or subcutaneousadministration. The Microcrystal Technology is a unique delivery system in which a fine aqueoussuspension of drug is encapsulated in phospholipids by microfluidization. The… more
Company: Integrated Technologies For Agency/Program/Year/Phase: DOD / SBIR / 1993 / 2
Abstract: THE PURPOSE OF THIS WORK IS TO DEVELOP THE TECHNOLOGY FOR DESIGNING AND MANUFACTURING HIGH-PERFORMANCE AND HIGH-RELIABILITY MICROFLUIDIC COMPONENTS. IN THE PHASE I PORTION OF THE WORK, THE EMPHASIS IS ON MICROFLUIDIC DEVICE MODELING AND ON MICROFABRICATION METHODS. ONE… more
Company: Orbital Research Inc Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: MICROVALVES PREVIOUSLY MADE CANNOT BE RELIED UPON FOR LONG TERM TIGHT SHUTOFF. IF MICROFLUIDIC SYSTEMS ARE TO BECOME A REALITY, TIGHT SHUTOFF MUST BE ACHIEVED BY MICROMACHINED VALVES. ALTHOUGH SURFACES ON MICROVALVES IN THEORY SHOULD BE ATOMICALLY SMOOTH, THUS ALLOWING FOR TIGHT… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: …EES CENTIGRADE TO 45 DEGREESCENTIGRADE. RIBOFLAVIN WAS SELECTED AS A MODEL COMPOUND BECAUSE IT IS SIGNIFICANTLY LESS COSTLY THAN ANTITUMOR AGENTS. MICROSPHERES WILL BE PREPARED BY A SOLVENT EVAPORATION PROCESS THAT PRODUCES A MONOLITHIC DRUG POLYMER MATRIX. A NEW MICROFLUIDIZED… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: … RODENT FEED, AND THE CHRONIC TOXICITY OF THE CHEMICALS WILL BE EVALUATED. DURING PHASE I, MICROCAPSULES WILL BE PREPARED FROM VITAMIN A (RETINOL). THIS CHEMICAL WAS SELECTED AS A MODEL OF AN UNSTABLE TEST CHEMICAL THAT UNDERGOES RAPID PHOTODECOMPOSITION. A NEW, MICROFLUIDIZED… more
Displaying 676 – 697 of 697 Awards
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