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Note: The Award Database is continually updated throughout the year. As a result, data for a given year is generally not complete until April of the following year.

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Displaying 101 – 125 of 784 Awards
Company: GNUBIO, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … This is a Phase II SBIR proposal to increase the throughput of our DNA sequencing instrument to enable whole genome sequencing with high efficiency and accuracy for a cost of under 1000 per genome. In Phase I, we developed a working sequencing assay, a microfluidic… more
Company: NANOSORT, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … (~ 500,000) machines that require dedicated space and staff for their operation. We have invented and patented three techniques that enable the development of a sorting flow cytometer at a fraction of the cost and size of conventional instruments, using microfluidics to… more
Company: NANOSORT, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: Cancer is a complex and diverse disease whose treatment can be improved by more sophisticated early detection and monitoring. NanoSort, Inc. proposes to build a lab-on-a-chip microfluidic device platform that can detect and quantify up to 32 multiplexed analytes for the… more
Company: DAHL NATURAL Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … system optimization. Phase 2 (The System): Further development of electronic hardware to fabricate a 80 sensor multiplexed disposable array, automated delivery and clearance of fluid samples to the test sensor using a proprietary design for an electronic microfluidic pump… more
Company: DNA MEDICINE INSTITUTE Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … at the patient's side for point-of-emergency clinical decision making. This is in contrast to today's measurement technologies, which require abenchtop instrument and a trained technician. The central hypothesis for this Phase II SBIR effort is this: microfluidic… more
Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … technology widely utilized in newborn screening, but when applied to enzyme assays it is expensive, time consuming, and labor intensive. There is a need for an inexpensive, rapid, and automated technology for performing newborn screening assays. A digital microfluidic… more
Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: … suitable for universal bilirubin screening. Therefore, there is an immediate need to develop novel point of care technologies that will meet the AmericanAcademy of Pediatrics recommendation for bilirubin screening. Advanced Liquid Logic's digital microfluidic platform… more
Company: CFD RESEARCH CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): We propose to develop and demonstrate a novel microfluidic device and assay for selection and optimization of delivery vehicles, specifically non-viral vectors for drug delivery to tumors. Tumor drug delivery is a complex phenomenon affected… more
Company: CFD RESEARCH CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed… more
Company: CFD RESEARCH CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: …. Current methods and devices are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for deployment in military and other limited resource settings. To overcome these limitations, we propose to develop and demonstrate a microfluidic impedance… more
Company: CFD RESEARCH CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: … in electrochemical power sources, biomicrosystems, bioelectrochemistry, and system design has been assembled to accomplish these goals. BENEFIT: The major outcome of this project will be a completely enzymatic fuel cell coupled with a paper-based microfluidic… more
Company: ENERTECHNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: …rated with automation technology developed by the Pacific Northwest National Laboratory (PNNL) to produce a self-contained portable personal exposure sampling unit and a bench-top assay unit. Enertechnix will be responsible for the aerosol sampling and microfluidic components… more
Company: LUNA INNOVATIONS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: Luna Innovations is developing the field-deployable Portable Analysis of Toxic H2O Samples (PATHOS) that utilizes whole cells as extremely sensitive biological detectors of water toxicants via two different metrics (colorimetric and impedance), resulting in increased reliability and sensitivity to a… more
Company: GENEFLUIDICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … complements our ongoing NIAID Cooperative Agreement, An Integrated Diagnostic Biochip for Point of Care Pathogen Identification (U01 AI082457), for rapid molecular diagnosis urinary tract infections (UTI) using electrochemical biosensors integrated with microfluidics. Since… more
Company: GINER, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: … oxidize a mixture of fuels. The cathode complexes facilitate direct electron transfer for oxygen reduction reaction. The configured system does not require exogenous power for fuel delivery, and demonstrates a simple structure and easy operation. This microfluidic… more
Company: IMMPORT THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): We aim to develop a fully integrated microfluidic immunodiagnostic platform utilizing a novel air-liquid cavity acoustic transducer (ALCAT) technology pioneered in the lab of Dr Abe Lee. The diagnosis platform is basedon the well-established… more
Company: Gamma Dynamics LLC Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2
Abstract: … year, while adding minimal cost to building infrastructure. The commercialization path for this technology is through the Advanced Flat Glass segment of the Flat Glass market. In addition, this program will enhance scientific innovation at the Ohio Center for Microfluidic… more
Company: INTELLIGENT OPTICAL SYSTEMS, INC. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: …ise in lateral flow test strip (LFTS) assays by integrating an LFTS with a cell phone for the quantitative measurement of blood-based biomarkers. Our innovative and extremely cost-effective multi-analyte LFTS approach is imminently suited for space travel. All "… more
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … disposable reagent cartridge. A key factor enabling this game changing technology is the development of a novel enzyme that converts RNA to DNA and isothermally amplifies it in minutes. These attributes have allowed the design of a device that does not use any microfluidics,… more
Company: NESHER TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: …. NTI recently achieved expansion from 2-color (2c) to 4-color (4c) ALEX, substantially expanding its multiplexing power. Furthermore, recent work by our consultants Profs. Stephen Quake and Shimon Weiss demonstrates successful merging of microfluidics-based sample… more
Company: NESHER TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: … power, and demonstrated diagnosticutility for ultrasensitive miRNA quantification at clinically relevant concentrations without amplification. Furthermore, recent work by our consultants Steve Quake and Shimon Weiss shows i) combination of microfluidics-based sample… more
Company: NetBio, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … SBIR goal is to develop a rapid, cost-effective, sensitive and specific Ct POC diagnostic system to increase early detection, inform appropriate treatment, reduce the rateof infections, and thereby reduce sequelae. In SBIR Phase I, we developed an initial microfluidic NAAT… more
Company: P2D, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: …e in treating sTBI-associated HICP onset. Our proposed SBIR research and commercialization program is to develop a blood and CSF POC neuromonitoring device to predict and identify sTBI patients who will experience delayed HICP onset later. The POC device is based on microfluidic… more
Company: SILOAM BIOSCIENCES Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: …, can work with low sample volumes are typically expensive and have limited sensitivity. Ultra-high sensitivity platforms are also expensive and typically require complex sample prep steps and large sample volumes. Siloam has developed a novel Optimiser microfluidic assay… more
Company: SOUTHWEST SCIENCES, INC. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1
Abstract: DOEs efforts to monitor legacy sites for groundwater contamination would benefit from turn-key systems that can measure metal contaminant concentrations in situ. Southwest Sciences proposes to develop a micro-fluidic sensor for measuring heavy metals in groundwater by measuring… more
Displaying 101 – 125 of 784 Awards
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