Abstract:…rated with automation technology developed by the Pacific Northwest National Laboratory (PNNL) to produce a self-contained portable personal exposure sampling unit and a bench-top assay unit. Enertechnix will be responsible for the aerosol sampling and microfluidic components… more
Abstract:This Small Business Innovation Research Phase I project will develop a microfluidic in-situ Transmission Electron Microscope (TEM) specimen holder with accurate temperature and pressure measurement and control abilities. The inability to dynamically image materials at atomic… more
Abstract:…ess Innovation Research (SBIR) Phase I project proposes to develop an entirely new platform for the molecular diagnostics of cancer exploiting a new Surface Enhanced Raman Scattering (SERS) enhanced Ligase Detection Reaction (LDR) and an optically active microfluidic chip. Since… more
Abstract:… sensor fabrication and sensor evaluation, including sensitivity, specificity,detection limit, linearity, accuracy, dynamic range, repeatability, precision, accuracy, interference, cross-reactivity, drift, and sensor calibration. Second is the development of microfluidic… more
Abstract:…, as well as in high throughput applications for target validation in pharmaceutical industry. Specific aims of this SBIR proposal include: 1) Design andmanufacture miniaturized circuits for impedance measurements, 2) Design and manufacture CO2- impervious microfluidic… more
Abstract:… single sensing endpoint (impedance). With the advances in lab-on-a-chip technologies, cell maintenance systems that are integrated into the chip become possible. Therefore, it is highly desirable to merge advances in label-free multiparametric cellular sensing with … more
Abstract:DESCRIPTION (provided by applicant): Microfluidic systems are emerging as critically important tools for high throughput cell based analysis for applications including genotyping, sequencing, gene expression analysis, nucleic acid amplification, and diagnostics. Lab-on-a-chip… more
Abstract:…w multichannel micro capillary electrochemical driven device that uses electrokinetic induced electroosmotic flow for both metal and organic separation and identification. This unit is highly synergistic to many of the complementary processing and analytical microfluidic device… more
Abstract:… a strong need for making smaller and more tightly spaced channels in their cooling devices to significantly enhance their thermal performance. Additionally, many micro-machining centers are machining 3D channels with 50-100 micron channel widths for micro-fluidics… more
Abstract:… seen a major European Chlamydia trachomatis strain), incapable of strain typing (making reliable epidemiology studies and contact tracing impossible), and incapable of determining drug resistance profiles. NetBio is proposing to develop an inexpensive microfluidics-based… more
Abstract:…, multiplex PCR amplification using NDIS/CODIS-compatible STR primer sets, electrophoretic length separation of PCR products, and laser-induced fluorescence detection of the products to yield electrophoretic traces. These subsystems will be based on microfluidic… more
Abstract:… technology for automated machining features between 50 to 100 micrometers. The challenge lies in the development of nozzles with beam diameters less than 100 micrometers. Several issues must be resolved due to the complexity of the supersonic, 3-phase, and microfluidic… more
Abstract:The overall goal of this Phase II project is to develop a prototype micro-fluidic sampling system that will lead to a field-deployable detection system capable of detecting low ppb levels of chemical warfare agents (CWAs) and explosive precursors in water. The proposed work… more
Abstract:…f the molecular machines underlying cellular function. Scanning transmission electron microscopy (STEM) of samples in liquid environments opens up the possibility of imaging molecular complexes in intact cels with nanometer resolution. Leveraging advances in micro-fluidics… more
Abstract:…. A small, disposable sensor chip will be sensitized to detect an array of 13 pathogens in a single sample in less than 15 minutes. This panel can readily be extended to detect hundreds of analytes simultaneously (depending on target requirements). A microfluidic… more
Abstract:… modifications in gel electrophoresis. Potential future applications of the optical module will improve multicolor fluorescence detection in immunohistochemistry and analysis of fluorescent proteins in cells and tissues, microplate reading and microfluidic analysis for… more
Abstract:… or does not have the capability to determine the concentration of specific nutrients. Project Objectives: It is the objective of this project to develop a rugged, compact, inexpensive and yet easy to use optical fiber sensor that uses lab-on-a-fiber concept and microfluidic… more
Abstract:… in the field if repairs are necessary. TA & T will develop UV-curable, CNT-filled oligomer/monomer blend coatings with high flexibility, erosion resistance, and conductive properties. Two innovative dispersion methods, resonant acoustic mixing and microfluidizer… more
Abstract:… in less than 2 hours. In Phase II, we propose to integrate the 96-channel CFM from Phase I with a commercial SPR imager to enable automated interaction analysis in a highly parallel format. The followingspecific aims detail the combination of Wasatch's microfluidic… more
Abstract:DESCRIPTION (provided by applicant): Lung transplants remain the final treatment for many conditions. However, appropriate and available lungs are far fewer than the number of people who need them, leaving many patients to further deterioriate or die while waiting for a transplant. Moreover, there… more
Abstract:DESCRIPTION: The fundamental goal of this program is to develop a microfluidics-based artificial kidney that minimizes exposure of blood to artificial surfaces and provides continuous perfusion in a compact, wearable device. This device will provide treatment at low flow rates… more
Abstract:… address these needs, Infoscitex Corporation (IST) and Claros Diagnostics propose to develop an aptamer base POC diagnostic system which leverages IST"s proprietary rapid isolation of DNA aptamers (RIDA) process with Claros Diagnostics"mature microfluidic based POC… more
Abstract:… filtering method
combined with a multistage electrodeless dielectrophoretic separation technique. Separation of biological material is followed by biomaterial
purification, elution, concentration, and collection. The MDSP system will be composed of a reusable microfluidic… more
Abstract:… result, new tools are needed to accelerate the assessment of drug candidate toxicity earlier in the drug development process. To address this Chemical/Bio Defense (CBD) need, Physical Optics Corporation (POC) proposes to develop a new three-dimensional Microfluidic Platform… more
Abstract:…, similar to the transition from electron tubes to integrated circuits in electronics. The spectrometer is an optical chip just a few millimeters in size; it can be implemented to detect any desired substance. The spectrometer can potentially be integrated with microfluidic… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.