Abstract:This Small Business Innovation Research Phase I project aims to develop low-cost light-weight miniaturized instruments, based on micro-electro-mechanical resonant nanobalances, for real-time monitoring of concentration, and size distribution of airborne micro/nano-particles.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop novel superparamagnetic biocompatible cell-penetrant bioactive nanoparticles for reprogramming human somatic cells and generation of pluripotent stem cells with intact genomes. To demonstrate technical feasibility,… more
Abstract:This Small Business Innovation Research Phase I project strives to control the chemical properties and the morphological structure of a polymer nano-composite surface, at scales ranging from nanometers to the macroscopic, to achieve superhydrophobic and icephobic properties… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will continue the development, validation, and full-scale testing of a new patent-pending nanoparticle-reinforced composite product for the repair and rehabilitation of piping and other civil infrastructure systems. The overarching goal… more
Abstract:… differentiate between latent and active TB infection. There is an urgent need for inexpensive, sensitive, specific, rapid, simple to perform, point-of-care assay for correct TB diagnosis. Phase I research will entail: (1) developing an electrochemical multiplex nano-bead… more
Abstract:…, thus reducing the logistical footprint and associated costs of providing fuel to the military. Phase I activities will include development of concept designs utilizing commercially available technologies and demonstrating the ability to fabricate the necessary … more
Abstract:ABSTRACT: There has been growing interest in nano- and micro-scale testing of materials at increasingly elevated temperatures. However technological obstacles have limited the range of materials that can be tested and limited the temperatures that can be successfully reached… more
Abstract:ABSTRACT: An innovative high power photonic curing process incorporating broadband light including ultraviolet (UV) is proposed for low temperature sintering of ceramic materials on metallic substrates. New high power ultraviolet (UV) flash lamps developed and integrated with a system that permits… more
Abstract:…. A multibody system is any physical system which may be modeled as interconnected rigid or flexible bodies which includes all manner of machines and mechanisms ranging from terrestrial vehicles and space structures to manufacturing equipment, robots, micro, nano, molecular,… more
Abstract:… and to supply electronic systems onboard, thereby extending watercraft range and operational capability. Phase I of the project will develop and validate the details of our energy harvesting system concept. Our approach will require assembly of special materials using … more
Abstract:… agents optimized for molecular imaging, long shelf-life, and overall stability. Our particles would be the first commercial agents designed and developed specifically to support molecular, dual-contrast USPA imaging. Proprietary and Confidential Property of NanoHybrids LLC … more
Abstract:DESCRIPTION (provided by applicant): Multiplexed Onchip Nanomagnetic Immunoassay for Toxin Reporting (MONITOR) Micro/Nano engineering techniques such as lab-on-a-chip technologies and nanoparticulates sensors are emerging as the next revolution tools for integrated high… more
Abstract:…, Newomics Inc. proposes to develop fully- integrated microfluidic chips, as a new platform for rapid and sensitive biomonitoring in humans. The chip is built on micro fabricated monolithic multinozzle emitters and multinozzle emitter array chips for nano-ESI-MS,… more
Abstract:… imaging advantages that can be gained with a phase plate with none of the significant problems associated with Zernike and Boertsch phase plates. PUBLIC HEALTH RELEVANCE: IDES will provide an invaluable imaging tool for medical, pharmaceutical, and nano-… more
Abstract:…ly-integrated sequencing system that encompasses the entire workflow and consists of several innovative sample preparation and sequencing modules that are being developed in parallel. One of the core components of the sequencing module will be two novel electric nano-biosensors… more
Abstract:… had neutralizing antibody titers against AAV1. Nanocor Inc. has developed a chimeric of AAV that more specifically targets the heart and escapes the inherent immunity in patients. We have proposed to use of these novel chimeric vectors, which are also known as Bio Nano… more
Abstract:The Hsp90 inhibitor 17-DMAG will be encapsulated in a nano-sized liposome formulation that is long-circulating with controlled drug release properties in tumor tissue. Reformulation of 17-DMAG in a nanoliposome will increase the dose intensity of 17-DMAG in solid tumors while… more
Abstract:… range are needed. SA Photonics technologies have enabled the construction of high performance hoop-strain-sensing systems. SA Photonics will construct the system using our RIS, ND and SBE technologies. The hoop-strain-sensing system will have sensitivity down to … more
Abstract:… security, and the overall economy. Its advantages will attract strong interest from the DOE, private sector/industry, and public and private research labs. eSPMs heretofore unavailable capabilities enable the study of catalytic reactions and hydrogen storage at the … more
Abstract:…ion to an unanswered materials characterization challenge of paramount importance to our national security by improving unique improvements in our capability to screen for and reverse engineer high energy density materials, radar absorbing materials, biologically active … more
Abstract:… with no required maintenance. TEPG also has the potential of enabling large-scale electric power generation. We propose to continue are on-going research of PbTe single crystals and investigate the FAST technique, developed by Penn State Univ., to produce bulk … more
Abstract:… molecularsophistication and prognostic power that is not possible with any other detection system, biomarkers or correlative gene expression signatures. To achieve this, we will combine transformative new technological platforms developed at the Salk, UCSD, and NanoSort that… more
Abstract:DESCRIPTION (provided by applicant): Lab-on-a-chip flow cytometer using color-space-time (CoST) coding method NanoSort, LLC RESEARCH and RELATED Other Project Information 7. PROJECT SUMMARY Fluorescence-activated-cell-sorting (FACS) or flow cytometry enables clinicians and… more
Abstract:Atomic layer deposited functional nano-film technology is used to manufacture Microchannel plate (MCP) devices capable of high gain / low ion feedback operation, on glass capillary array substrates, as a means to replace MCP chevron configuration and enable direct photocathode… more
Abstract:…y available nitride foundry capabilities and pure research by utilizing proven process technology at RFMD for processes not requiring deep, submicron lithography and utilizing state-of-the-art nanofabrication technology available at the University of Minnesota's … more
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