Abstract:…imulated skin/muscle tissue at the correct/incorrect angle Ability to incorrectly/correctly insert the needle through the simulated skin/muscle tissue and simulated bone using the EZ IO drill Ability to anchor the catheter into the simulated arm Ability to attach a syringe… more
Abstract:… cables that have a critical current density of at least 300 A/mm2 at 20 T from which the next generation of accelerator magnets can be built. We will accomplish this by optimizing the cable layout when using superconducting tapes that have thin layers of copper and contain thin… more
Abstract:…. In Phase I, we will establish the feasibility of the proposed microfluidic automation technology by engineering and screening E. coli cells for the production of fatty acid ethyl esters (FAEE). By performing all three key operations: 1) construction of a plasmid containing… more
Abstract:… in particular is a powerful, versatile exciting platform to expose students to many facets of science and engineering, as it is truly a multidisciplinary endeavor. The anticipated Phase I results are beta tests of a proof-of-concept engineering design game containing a… more
Abstract:… Americans have peripheral vascular disease (PAD). Percutaneous transluminal artery (PTA) treatment of severe PAD involves the use of balloons and stents, but delivery of these therapies is often suboptimal due to inaccuracies in angiographic assessment of vessel size or a… more
Abstract:…ellent preliminary results, and the previously known safety of a related system, the CB catheter system is expected to provide highly accurate and repeatable real-time digital display of balloon size across theentire coronary stent range in any type of diseased vessel condition… more
Abstract:… particles with precisely engineered physical characteristics. Under SBIR Phase I Lab-to-Marketplace funding, we designed and optimized a multi-nozzle unit consisting of 12 individual nozzles capable of producing uniform, poorly water-soluble drug-containing… more
Abstract:…conduct a fidelity trial to test its effectiveness on new SHARE counselors. Specific Aims are to: 1) Produce a complete 10-module SHARE web course and develop a website that provides support and supervision materials; 2) Complete development of the app that will contain key… more
Abstract:…ng multiple drugs taken several times daily, 2) administration-- visually impaired patients often cannot correctly identify medication and read labels, 3) lability-- many drugs react adversely to extreme conditions, and 4) lack of patient options-- no multi-drug container exists… more
Abstract:… amounts of adsorbed natural gas storage than previously possible, with a target of 235 V/V, while maintaining economic viability. Projections for U.S. on-road heavy-duty natural gas vehicles would reduce petroleum consumption by approximately 1.2 million barrels of oil per… more
Abstract:…What is unique and noteworthy about our proposal is that these particular biostability compounds not only protect soluble analytes such as plasma proteins, but appear to act on the entire cellular fraction, including whole cells and the analytes associated or contained within… more
Abstract:… of bevacizumab monoclonal therapy is associated with discomfort, significant risks and high cost and administration of this antibody leads to high peak levels that may be associated with toxicity and prolonged troughlevels that are sub-therapeutic. This SBIR contains the… more
Abstract:… second goal is to build a highly intuitive and high-quality visualization platform using OpenGL for displaying real-time metrics of streaming data. AccelerEyes develops ArrayFire, which is the largest software library for GPU and accelerator computing and contains built-in… more
Abstract:… resistance tires have yielded 7% fuel costs savings on Army demonstrator vehicles. However, tire changes to improve rolling resistance affect other areas of tire performance. A tire is a composite structure made up of different rubber compounds that contain reinforcing… more
Abstract:…d system can meet the targeted goals for LCC. With regard to manufacturability our monolithic integrated optical approach means that once NRE associated with mastering is completed component replication costs are greatly reduced since the optical complexity is contained in the… more
Abstract:…mW energy. This signal is combined with the second laser on a photodiode which mixes the two signals in a homodyne detection approach. The second laser can be thermally turned to different harmonics which allows it to interrogate the primary laser signal which contains the mmW… more
Abstract:Ballistic and blast protection of both the crew and vital equipment onboard U.S. Navy surface ships and carriers is a critical component in the design of topside structures on these vessels. Materials such as glass, Plexiglas and polyurea are being considered and implemented for… more
Abstract:… omni-directionally maneuvering operations. Selected design candidates will be evaluated with respect to their ability to provide an assured capability of acquiring and lifting both palletized and uniquely shaped payloads from the confines of a standard ISO container or from… more
Abstract:… field of regenerative medicine and have significant benefits on the commercial development of other tissue engineered organs. By creating scaffolds with synthetic polymers, we are able to create the framework of nearly any type of organ in the body ranging from blood vessels to… more
Abstract:… dose. The promise of nanomedicine circumvents drug inactivation as it circulates through the body with a concomitant decrease in side effects, increases anticancer drug accumulation in tumors and improves treatment of cancer. NMI designed a nanomedicine, which contains the… more
Abstract:… batches of IPs and flexible enough to allow for multiple test molecules, such as phytase, probiotics or anti-virals.
ZBI proposes to develop the prototype manufacturing line, train employees to operate the line, manufacture multiple IP formulations containing anti-virals,… more
Abstract:… for infants. The goal of this project is to design, test, and produce a life support system specifically for infants (1 through 10 kg, 1 day to 2 years age); we call this MiniECMO. Phase l aims include integration of the MC3 BioLung and MPump devices with cartridge heat… more
Abstract:… most natural state (i.e., fetal circulation), and is truly innovative and offers many therapeutic opportunities when compared to current clinical practice with mechanical ventilation. Phase l aims include integration of the MC3 BioLung and MPump devices with cartridge heat… more
Abstract:… NIDDK which is explicitly interested in the development of innovative technologies for the prevention and treatment of hypoglycemia. The first objective of this program is to manufacture a batch of Xeris'non-aqueous glucagon rescue formulation in pre-filled syringes,… more
Abstract:… the DoD requirements by leveraging our deep technical expertise in materials and fire safety. The selected approach is to combine the properties of several low-cost, lightweight and off-the-shelf materials in a laminate structure which will be able to channel and contain… more
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