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Displaying 5626 – 5650 of 6409 Awards
Company: BIOTEK, INC. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: … INSUFFICIENT SUPPLY OF DONOR BONE, THE POSSIBILITY OF TRANSMISSION OF PATHOGENS SUCH AS HEPATITIS B OR HUMAN IMMUNODEFICIENCY VIRUS (HIV). DEMINERALIZED BONE MATRIX, ALTHOUGH SUCCESSFUL, DO NOT PROVIDE IMMEDIATE STRUCTURAL STABILITY OR ABILITY TO SUPPORT SOFT TISSUE.… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: DOE / SBIR / 1992 / 2
Abstract: … (BPA), CAN ALSO SELECTIVELY LOCALIZE IN SKIN CANCERS SUCH ASMALIGNANT MELANOMA. UPON IRRADIATION BY A THERMAL OR EPITHERMAL NEUTRON BEAM, THE COMPOUND PRODUCES LOCALIZED RADIATION OF ONLY ONE OR TWO CELL WIDTHS THAT KILLS CANCER CELLS WITHOUT DAMAGE TO HEALTHY TISSUE AND… more
Company: Boston Advanced Tech Inc. Agency/Program/Year/Phase: NASA / SBIR / 1992 / 2
Abstract: … ANALYSIS WILL BE PERFORMED DIRECTLY THROUGH THE SKIN BY USING LIGHT FROM A LASER DIODE ARRAY THAT IS REFLECTED FROM A PROMINENT VEIN NEAR THE SKIN SURFACE, IN EITHER THE WRIST OR ANKLE REGION OF THE BODY. THE LASER DIODES WILL OPERATE AT LOW POWER, CAUSING NO TISSUE INJURY,… more
Company: Bozeman Bio-tech Inc. Agency/Program/Year/Phase: USDA / SBIR / 1992 / 1
Abstract: … PERSISTENT AGENT, ACTS TOO SLOWLY, REQUIRING ABOUT 3 WEEKS TO BEGIN KILLING. IN PRELIMINARY USDA TESTS, NOSEMA ACRIDOPHAGUS HENRY (NA), ANOTHER MICROSPORIDIAN, DEMONSTRATED SPEED AND VIRULENCE, ACTING IN ONE-THIRD THE TIME OF NL, AND ATTACKED A MUCH BROADER TISSUE RANGE. NA… more
Company: Brewer Science Incorporated Agency/Program/Year/Phase: NSF / SBIR / 1992 / 1
Abstract: … TECHNIQUE KNOWN AS LIGA MICROFORMING. THE ULTIMATE GOAL OF THIS PROGRAM (PHASES I AND II) IS THE DIRECT FABRICATION OF WAVE GUIDE STRUCTURES BY X-RAY OR DEEP-UV LITHOGRAPHY. NEW RESIST MATERIALS WITH OUTSTANDING SENSITIVITY, CONTRAST,RESOLUTION, AND ADHESION ARE REQUIRED… more
Company: Brookwood Biomedical Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: …XPAND HEMATOPOIETIC STEM CELL POPULATIONS IN VITRO WOULD BE OF OBVIOUS ADVANTAGE IN BOTH AUTOLOGOUS AND ALLOGENEIC BONE MARROW TRANSPLANTATION. STEM CELL PROPAGATION REQUIRES INTERACTION WITH ADHERENT STROMAL SUPPORT CELLS AND CAN BE PERFORMED IN CONVENTIONAL TISSUE CULTURE AND… more
Company: CALBIOMARINE TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: … ECTEINASCIDIA TURBINATA. THE PHASE I STUDY WILL EXAMINE THE EFFECTS OF 6 ENVIRONMENTAL FACTORS ON ECTEINASCIDIN PRODUCTION: LIGHT INTENSITY, TEMPERATURE, FEEDING RATE, INORGANIC NITROGEN CONENTRATION, INORGANIC PHOSPHATE CONCENTRATION AND SIMULATED PREDATION TISSUE DAMAGE.… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: Ceramed Corporation Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: FACILITATING THE IMMIGRATION OF OSTEOGENIC CELLS FROM THE SURROUND HOST TISSUE WITH SUBSEQUENT INCREASE IN BONE INGROWTH INTO A MORE BIOLOGICALLY ACTIVE NATURAL SCAFFOLD IS OF CLINICAL SIGNIFICANCE. OF PARTICULAR IMPORTANT IS ITS APPLICATION TO THE ELDERLY POPULATION WHO REQUIRE… more
Company: Charles Evans & Associates Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: … FOCUSES SECONDARY IONS PRODUCED BY BOMBARDMENT WITH A CS(+) PRIMARY BEAM. THIS INSTRUMENTATION CAN ALSO PRODUCE ION IMAGES USING A RASTERED MICROFOCUSSED PRIMARY ION BEAM, A LIQUID METAL ION GUN WHICH PRODUCES (69)GA(+). SIMS ANALYSIS OF VARIOUS BIOMOLECULES IN TISSUE-LIKE… more
Company: Civilized Software, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 2
Abstract: … ON ARBITRARY ONE- ANDTWO-DIMENSIONAL SPATIAL DOMAINS. PDE'S OF THE TYPES TO BE HANDLED BY THE PDESYS SOFTWARE ARE UBIQUITOUS IN BIOMEDICINE, SCIENCE, AND ENGINEERING. HEAT TRANSFER, ELECTRODIFFUSION, REACTION DIFFUSION, NERVE-IMPULSE TRANSMISSION, CAPILLARY/TISSUE EXCHANGE,… more
Company: Colla-tec, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 2
Abstract: THE CENTRAL PURPOSE OF THIS RESEARCH IS TO TEST THE EFFICACY OF A COLLAGEN-BASED TUBULAR PROSTHESIS TO PROMOTE AXONAL REGENERATION IN THE PERIPHERAL NERVOUS SYSTEM IN VIVO. THE PROSTHESIS IS NONTOXIC AND BIODEGRADABLE AND IS FABRICATED FROM NATURAL CONNECTIVE-TISSUE COMPONENTS.… more
Company: Copley Pharmaceutical Inc Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: A MEDICATED ORAL PATCH HAS BEEN DEVELOPED AT COPLEY PHARMACEUTICALS, INC. WHICH HAS GOOD ADHESION TO THE GINGIVAL MUCOSA AND RAPIDLY DELIVERS DRUG THROUGH THIS TISSUE. PROCHLORPERAZINE IS AN ANTI-EMETIC DRUG THAT SHOULD BE READILY DELIVERED THROUGH THIS MUCOSAL TISSUE… more
Company: Cynosure, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE GOAL OF THIS PROJECT IS TO DEVELOP A METHOD TO IMAGE STRUCTURES UNDER LIVING TISSUE WITH HIGH RESOLUTION USING OPTICAL TECHNIQUES. RECENT EXPERIMENTAL RESULTS HAVE DEMONSTRATED THAT ONE CAN IMAGE THROUGH TURBID MEDIA USING OPTICAL HETERODYNE TECHNIQUES. THESE EXPERIMENTS… more
Company: Eggers And Associates Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: A DEVICE AMD METHOD FOR MEASURING THREE-DIMENSIONAL NEUTRON DISE DISTRIBUTION IN-PHANTOMS ON A REAL-TIME BASIS WILL BE DEVELOPED. THIS METHOD OFFERS THE ADVANTAGES OF NEUTRON DETECTORS WHICH ARE TISSUE-EQUIVALENT AND MINIMIZE DISTURBANCE TO NEUTRON SCATTERING WITHIN A… more
Company: Federal Electro-optics Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: …, THE SYSTEM HAS THE POTENTIAL TO FURNISH TRUE "COLOR" INFORMATION IN VERY NARROW BANDS, A CONCEPT TERMED HYPERSPECTRAL IMAGING. FEO BELIEVES THIS INFORMATION COULD OPEN NEW AREAS OF DIAGNOSTIC MEDICAL IMAGING LEADING TO IMPROVED DETECTION AND DIAGNOSIS OF ABNORMAL TISSUE AND… more
Company: FOSTER-MILLER, INC. Agency/Program/Year/Phase: DOT / SBIR / 1992 / 1
Abstract: …, AND BEFORE THE STRUCTURAL INTEGRITY OF THE AIRCRAFT IS SIGNIFICANTLY DIMINISHED. SPECIFIC GOALS OF THIS PROGRAM ARE TO DESIGN FIBER OPTIC SENSORS THAT CAN BE EMBEDDED IN AIRCRAFT JOINTS THAT CAN DETECT DISBONDING AND THE ONSET OF CORROSION IN THE PRESENCE OF ADHESIVES AND… more
Company: Gait Scan Inc. Agency/Program/Year/Phase: NASA / SBIR / 1992 / 2
Abstract: BONE WEAKENING IS A CONCERN FOR ASTRONAUTS, WHO NOW EXERCISEIN FLIGHT TO PREVENT LOSS OF BONE IN THE LEGS AND FRACTURE ON LANDING. USING INNOVATIVE METHODOLOGY, THIS PROJECT WILL DESIGN AN INSTRUMENT THAT PROVIDES DIRECT, NON-INVASIVE, ACCURATE, AND REPRODUCIBLE MEASUREMENTS OF BONE STIFFNESS, A… more
Company: Gilead Sciences Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: …ION OF HUNDREDS OF COMPOUNDS FOR CELLULAR PERMEATION WITH A FLUORESCENT MICROSCOPY TECHNIQUE TO DETERMINE CELLULARLOCALIZATION OF FLUORESCENTLY LABELLED NUCLEIC ACID ANALOGUES. THE COMPOUNDS FOUND ACTIVE IN THE INVITRO TRANCRIPTASE ASSAY WILL SUBSEQUENTLY BE EVALUATED IN TISSUE… more
Company: Giner, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 2
Abstract: … RATIO. DURING PHASE I, THE OPTIMUM MATERIAL AND ELECTRICAL PARAMETERS WILL BE CHOSEN BASED EXCLUSIVELY ON IN VITRO LABORATORY TESTING OF A MACROSENSOR. WORK DURING PHASE II WILL CONCENTRATE ON TRANSLATING THIS TECHNOLOGY INTO AN IMPLANTABLE SENSOR FOR BLOOD AND/OR TISSUE… more
Company: Gravi-mechanics Company Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: A NEW AND NOVEL FLOW THROUGH BIOREACTOR WHICH IS BROADLY APPLICABLE TO CELL AND TISSUE CULTURE FOR BOTH RESEARCH AND INDUSTRIAL APPLICATIONS IS DESCRIBED. USING BIOREACTORS OF THIS DESIGN, THE REQUIRED PROTOCOL FOR OPTIMIZED PRODUCTION OF MICROTUBERS OF SOLANUM TUBEROSUM WILL BE… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: … OF THE PACIFIC YEW TREE, TAXUS BREVIFOLIA. THE APPLICANT WILL PREPARE A THIOETHER-LINKED BISPECIFIC ANTIBODY WITH DIAL SPECIFICITY FOR TAXOL AND HUMAN CANCER CELLS. IT IS ASSERTED THAT THIS BISPECIFIC ANTIBODY WILL POTENTIATE THE ACTION OF TAXOL IN TARGET TISSUE, MINIMIZE… more
Company: Hipple Cancer Research Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: … IMMUNE SYSTEM OF THE PATIENTS AND THUS, IT POSES A CONTINUOUS THREAT TO AIDS PATIENTS. AN ALTERNATIVE TREATMENT USING RECOMBINANT INTERFERON-GAMMA (IFN-GAMMA) HAS BEEN PROPOSED SINCE IFN-GAMMA, A CD4+T CELL PRODUCT, BLOCKS THE GROWTH OF T GONDII IN A VARIETY OF TISSUES AND… more
Company: Houston Biotechnology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 2
Abstract: THE CILIARY GANGLION INNERVATES SEVERAL IMPORTANT EYE TISSUES, INCLUDING THE CILIARY MUSCLE AND BODY, AND HAS BEEN SHOWN TO REGULATE AQUEOUS OUTFLOW AND ACCOMMODATION. THE EYE DISORDERS, GLAUCOMA AND PRESBYOPIA, MAY INVOLVE THE CILIARY GANGLION THROUGH ITS REGULATION OF AQUEOUS… more
Displaying 5626 – 5650 of 6409 Awards
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