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Displaying 6001 – 6025 of 6409 Awards
Company: FOSTER-MILLER, INC. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 2
Abstract: GLASS FIBER-REINFORCED THERMOPLASTIC RESIN COMPOSITES CURRENTLY SHOW UNSATISFACTORY PERFORMANCE AS A RESULT OF INADEQUATE ADHESION AT THE FIBER/RESIN INTERFACE. INTERFACE MODIFICATION BY APPLICATION OF HIGH TEMPERATURE POLYIMIDE RESIN COATINGS TO GLASS FIBERS WILL GREATLY… more
Company: FOSTER-MILLER, INC. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: …CURRENT MATERILS AND HIGH TENSILE STRENGTH). WE WILL USE INNOVATIVE POLYMER PROCESSING TO MAKE A BIAXIALLY ORIENTED LCP COATING WHICH WILL ACTUALLY CARRY TENSILE AND SHEAR LOADS ALONG WITH THE GLASS FIBER. THE LCP COATINGS WILL BE STRIPPABLE AND PROVIDE GOOD ADHESION TO THE… more
Company: Plant Genetics Inc Agency/Program/Year/Phase: USDA / SBIR / 1989 / 1
Abstract: COATED SOMATIC EMBRYOS OR "SOMATIC SEEDS" PROVIDE A METHOD TO DIRECTLY DELIVER PLANT MATERIAL FROM TISSUE CULTURE TO THE GREENHOUSE OR FIELD WITHOUT THE LABORIOUS AND EXPENSIVE STEP OF FORMING TRANSPLANTS. DESICCATED SOMATIC SEEDS WOULD HAVE MANY ADVANTAGES OVER HYDRATED SOMATIC… more
Company: Precision Optics Corpon Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: … AT TWO OR MORE DIFFERENT WAVELENGTHS) CAN BE MADE WILL ADD AN IMPORTANT NEWDIMENSION TO GASTROINTESTINAL FIBEROPTIC DIAGNOSES. SUCH PROCESSING OF SPECTRAL IMAGES WILL ENABLE THE DIAGNOSTICIAN,DURING ROUTINE ENDOSCOPIC EXAMINATIONS, TO DETECT LOCATIONS IN TISSUE WHERE… more
Company: Proteins International Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: … CONTAMINANTS OF THE HUMAN ENVIRONMENT. THE SIMPLEST EXAMPLES OF SUCH COMPOUNDS ARE MALONDIALDEHYDE, ACROLEIN, AND METHYL GLYOXAL. MALONDIALDEHYDE IS A PRODUCT OF LIPID PEROXIDATION AND PROSTAGLANDIN BIOSYNTHESIS AND IS PRESENT IN VIRTUALLY ALL MAMMALIAN TISSUES. METHYL… more
Company: Research Biochemicals, Agency/Program/Year/Phase: NSF / SBIR / 1989 / 2
Abstract: …OUNDS WILL BE COUPLED TO DOPAMINE AGONISTS (THERAPEUTIC DRUGS FOR PARKINSON'S DISEASE) AND ANTAGONISTS (THERAPEUTIC AGENTS FOR SCHIZOPHRENIA). WE WILL TEST THE AFFINITY AND SELECTIVITY OF THESE COMPOUNDS FOR DOPAMINE RECEPTORS. NEURAL MEMBRANES AT VARIOUS LEVELS OF TISSUE… more
Company: Research Biochemicals, Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: …OUNDS WILL BE COUPLED TO DOPAMINE AGONISTS (THERAPEUTIC DRUGS FOR PARKINSON'S DISEASE) AND ANTAGONISTS (THERAPEUTIC AGENTS FOR SCHIZOPHRENIA). WE WILL TEST THE AFFINITY AND SELECTIVITY OF THESE COMPOUNDS FOR DOPAMINE RECEPTORS. NEURAL MEMBRANES AT VARIOUS LEVELS OF TISSUE… more
Company: Research Opportunities, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: … BY CO-CURING OR COMPRESSION MOLDING. EVALUATION WILL BE BASED ON THERMAL AND MECHANICAL PROPERTIES MEASURED BEFORE AND AFTER THERMAL CYCLING, USING SEM E SPECIFICATIONS. OF PARTICULAR IMPORTANCE IS A COMPARISON OF PROPERTIES OF THE INTEGRAL DIELECTRIC/HEAT SINK WITH ADHESIVELY… more
Company: Resift Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: …, FRAGMENTATION, AND DETECTOR READOUT TO DETERMINE THE MOLECULAR WEIGHT AND AMINO ACID SEQUENCES OF THE NEUROPEPTIDES. THE STUDIES CONCERN THE DEMONSTRATION OF THE INSTRUMENT'S CAPABILITIES TO DETECT, IDENTIFY, AND SEQUENCE KNOWN PURIFIED PEPTIDES PRESENT IN NEURONAL TISSUE… more
Company: Resource Technologies Group Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: … AN IN VITRO EXPOSURE ASSAY FOR ADDUCTS, DETERMINE THE CONCORDANCE OF C-PROBE RESPONSE WITH CARCINOGENIC ACTIVITY OF THE TEST AGENTS AND CORRELATIONS WITH DNA ADDUCT FORMATION, AND EVALUATE THE FEASIBILITY OF C-PROBE FOR ADDUCT DETECTION IN BODY FLUIDS AND TISSUE SAMPLES.… more
Company: Ron-tron Engineering Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: … THIS AREA EMPLOYED U/V LASERS AS THE EXCITATION MEANS, TYPICALLY OF THE HELIUM-CADMIUM TYPE. THESE LASERS ARE QUITE DELICATE, EXPENSIVE, AND HIGHLY MONOCHROMATIC. EVENTUALLY, ALTERNATE U/V LIGHT SOURCES THAT CAN BE DIRECTED AND SCANNED SO THAT VERY SMALL AREAS OF TISSUE CAN BE… more
Company: Schonberg Research Corp. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: STEREOTAXIC RADIOSURGERY MAKES IT POSSIBLE TO DELIVER AN ABLATIVE DOSE OF IONIZING RADIATION WITH HIGH PRECISION TO BRAIN TUMORS WHILE MINIMIZING DAMAGE TO SURROUNDING NORMAL TISSUE. THIS PROJECT SEEKS TO DEVELOP A PROTOTYPE SYSTEM THAT UTILIZES NOVEL TECHNOLOGY TO DRAMATICALLY… more
Company: SCHWARTZ ELECTRO-OPTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: … CRYSTALCO:MGF2. APPLICATIONS REQUIRING PRECISE TISSURE ABLATION VIA FIBER DELIVERY, SUCH AS ANGIOPLASTY , APPEAR PARTICULAR APPROPRIATE FOR THE SYSTEM. THE CO:MGF2 LASER TUNABILITY , OVER THE SPECTRAL REGION FROM 1.7 TO 2.5 MICRONS, PROVIDES AND ADJUSTMENT OF THE TISSUE… more
Company: Sea Farm California A Division Agency/Program/Year/Phase: USDA / SBIR / 1989 / 1
Abstract: … OF THIS PROPOSAL IS TO DETERMINE IF THE ADMINISTRATION OF GNRHA TO FEMALE STURGEON WILL INDUCE ENDOCRINE MATURATION OF THE REPRODUCTIVE SYSTEM, AND BRING THE CULTURED FEMALE STURGEON INTO REPRODUCTION. TO DETERMINE EFFECTIVENESS OF THE GNRHA IMPLANTS, GONADAL TISSUE WILL BE… more
Company: Softbridge Microsystems Corp Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: … AS A CLINICAL TOOL FOR PLANNING COMPLEX MULTIFIELD RADIATION TREATMENTS. THIS MODEL IS A SIGNIFICANT PRACTICAL ADVANCE OVER MODELS THAT HAVE BEEN DESCRIBED IN THE LITERATURE, BECAUSE IT CAN ACCURATELY REPRESENT PARTIAL VOLUME-DOSE RESTRICTIONS FOR DIFFERENT TYPES OF TISSUES… more
Company: SPIRE CORPORATION Agency/Program/Year/Phase: NASA / SBIR / 1989 / 1
Abstract: EXTERNAL THERMAL PROTECTION FOR THE SPACE TRANSPORTATION SYSTEM ORBITER IS PROVIDED BY SPECIALLY MACHINED INSULATING TILES WHICH ARE INDIVIDUALLY MOUNTED BY ADHESIVE BONDING TO THE OUTER SKIN. DURING APPLICATION THE ADHESIVE MAY CRACK, FORM VOIDS, OR SIMPLY FAIL TO BOND TIGHTLY… more
Company: SPIRE CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: … BONDING (ESB) PROCESS FOR ATTACHING COVERGLASSES TO SPACE GALLIUM ARSENIDE (GAAS) SOLAR CELLS. IN THIS PROCESS, DIRECT CHEMICAL BONDS ARE FORMED BETWEEN THE GLASS AND THE TOP SURFACE OF THE CELL. SUCCESSFUL COMPLETION WOULD LEAD TO THE WORLD'S FIRST ADHESIVE-FREE… more
Company: SPIRE CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: … ION BEAM ASSISTED COATINGS OF SILICON NITRIDE, BORON NITRIDE, AND TITANIUM NITRIDE USING SIMULTANEOUS NITROGEN ION BOMBARDMENT AND VACUUM DEPOSITION OF SILICON, BORON, OR TITANIUM. THIS PROCESS RETAINS MANY OF THE ADVANTAGES OF ION IMPLANTATION (SUPERIOR ADHESION) WHILE… more
Company: Springborn Materials Science Agency/Program/Year/Phase: NASA / SBIR / 1989 / 2
Abstract: … FILLERS AND ADDITIVES KNOWN TO PROMOTE ELECTRICAL CONDUCTIVITY AND FLAME RETARDING PROPERTIES. THE EFFECTS OFTHESE ADDITIVES WILL BE EVALUATED QUANTITATIVELY TO ALLOW FOR FINAL OPTIMIZATION. ONCE GENERIC FLOOR COVERING MATERIAL TYPES ARE IDENTIFIED, STRUCTURAL ADHESIVES… more
Company: Springborn Materials Science Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: … IMPORTANT TO CONVERT TO WATERBORNE SYSTEMS TO MINIMIZE AIR POLLUTION IN THE VICINITY OF BASES APPLYING THESE COATINGS. THE PURPOSE OF THIS PROPOSAL IS TO DEVELOP A WATERBORNE URETHANE OR POLYSULFIDE THAT WILL MEET THE SPECIFICATIONS OF MIL-P-85853, I.E. METAL ADHESION,… more
Company: STRATAGENE Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: … DETECTION OF MUTATIONS. SEVERAL MODIFICATIONS OF THIS INTEGRATED LAMBDA VECTOR ARE PROPOSED THAT WILL ALLOW RAPID DNA SEQUENCE ANALYSIS OF MUTATIONS WITHIN THE TARGET GENE (LAC 1 REPRESSOR GENE). AFTER EXPOSURE TO A MUTAGEN, DNA SAMPLES ARE PREPARED FROM MOUSE TISSUES. PHAGE… more
Company: Synaptic Pharmaceutical Corp. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: …. IN AN EFFORT TO BETTER UNDERSTAND THESE POTENTIAL SITES FOR DRUG DEVELOPMENT, IT IS PLANNED TO CLONE AND CHARACTERIZE THE 5-HT1B AND 5-HT1D RECEPTORS FROM CDNA AND GENOMIC LIBRARIES. THE 5-HT1B AND 5-HT1D RECEPTOR CLONES WILL SERVE AS PROBES FOR DETERMINING TISSUE… more
Company: Synergen Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: SYNERGEN, INC.'S PROPOSED RESEARCH WILL DEVELOP, THROUGH RECOMBINANT DNA METHODS, NEW AGENTS TO CONTROL DENTAL PLAQUETHESE WILL CONSIST OF AN ENZYMATIC MOIETY OF THERAPEUTIC VALUE FUSED WIH AN ADHESIVE PEPTIDE THAT BINDS SPECIFICALLY AND STRONGLY TO DENTAL SURFACES. THE LATTER… more
Company: Synergen Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: NEUTROPHILS ARE A MAJOR CONTRIBUTOR TO THE CELLULAR DAMAGE THAT ACCOMPANIES REPERFUSION OF ISCHEMIC TISSUES. IT IS PLANNED TO CLONE AND PRODUCE THROUGH RECOMBINANT DNA METHODS A HUMAN PROTEIN THAT BLOCKS ATTACHMENT OF NEUTROPHILS TO ENDOTHELIAL CELLS IN VIVO AND THEREBY PREVENTS… more
Company: Synergen Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: …ROUTE OF ADMINISTRATION NEEDED TO STIMULATE THE FORMATION OF PILI-SPECIFIC ANTIBODIES IN THE NASOPHARYNX OF IMMUNIZED ANIMALS. THIS RESEARCH PROVIDES A BASIS FOR DEVELOPING VACCINES AGAINST HIB AND OTHER PATHOGENS THAT ADHERE TO SURFACES BY MEANS OF PILI OR ADHESION PROTEINS… more
Displaying 6001 – 6025 of 6409 Awards
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