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Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: … effects in humans. Unfortunately, high resolution thermal simulations are computationally very expensive. The goal of this project is to develop fast anatomy- and physiology-based computational tools for predicting whole-body and localized thermal response of tissue due to… more
Company: Coating Technology Solutions Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1
Abstract: …e and overall deposition rates. Diamonds radiation hardness and many other unique properties are propelling it to be utilized in increasingly important roles in DOE & apos;s discovery efforts in fundamental particle physics. Diamond also has important potential as a tissue… more
Company: COMPLEGEN, INC. Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: …y in patients with ALI/ARDS ranges from 30-60% and recovery often is associated with long term pulmonary and non-pulmonary morbidity. ALI/ARDS is characterized by an intense systemic inflammatory response leading to neutrophil infiltration of the lungs and lung tissue damage.… more
Company: Composite Technology Development, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: … are dry and chemically stable from cryogenic to elevated temperatures, simplifying installation and preventing thermal pump-out. Assembly, integration, and test time (AI & T) for CNT TIMs can be significantly reduced in comparison to liquid or adhesive TIMs. In… more
Company: SHARKLET TECHNOLOGIES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: …et Technologies Inc. (STI) aims to demonstratethe feasibility of integrating our proprietary Sharklet micro-pattern (Sharklet MP) into catheter surfaces to ultimately reduce CVC-related infection and to validate the ability of the Sharklet surface to prevent platelet adhesion… more
Company: CONFOMETRX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … segments separated by alternating intracellular and extracellular loop regions. GPCRs in vertebrates are commonly divided into five families by sequence and structural similarity, specified as Rhodopsin (Family A), Secretin (Family B), Glutamate (Family C), Adhesion, and… more
Company: CYTEX THERAPEUTICS INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: … unmet challenges to the medical community. The goal of this Phase I SBIR is to further the development of a method for themanufacture of a biologically-derived biomaterial that can maintain a pre-defined anatomical shape, while supporting the synthesis of a new tissue of a… more
Company: Daylight Solutions Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project will realize the full potential of a new quantum cascade laser (QCL) infrared microscope for medical diagnostics. Infrared microscopy can be used for tissue identification without staining, potentially allowing… more
Company: Deployable Space Systems (DSS) Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: ABSTRACT: Deployable Space Systems, Inc. (DSS), in partnership with Emcore Photovoltaics (EMCORE) and JDS Uniphase Corporation (JDSU) proposes the development of an adhesive-less photovoltaic panel assembly, termed"HSP"for High Survivability Panel. Space solar array… more
Company: Directed Vapor Technologies Internationa Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: … multi-functional protection. In this Phase I effort, novel processing techniques will be developed to enable the affordable, high performance manufacture of such systems using a physical vapor deposition based processing approach which enables enhanced coating adhesion and… more
Company: DYNAVAX TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Autoimmune diseases develop when the adaptive immune response targets self-antigens, leading to inflammation and tissue destruction. The innate immune system faces the same fundamental challenge as the adaptive immune system - distinguishing… more
Company: DYNAVAX TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Autoimmune diseases develop when the adaptive immune response targets self-antigens, leading to inflammation and tissue destruction. The innate immune system faces the same fundamental challenge as the adaptive immune system - distinguishing… more
Company: E PAINT CO. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: … and cost effective means of controlling biofouling that will significantly reduce the environmental impacts of maritime activities and result in a"Greener Navy". Phase I investigates the feasibility of developing biologically active polymers that target the adhesive… more
Company: Ecovative Design LLC Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2
Abstract: … engineering materials. Engineered woods are ubiquitous in the construction and furniture industries, but due to domestic indoor air quality regulations (Toxic Substances Control Act), these materials are being phased out or are forced to use expensive formaldehyde-free … more
Company: Electrical Geodesics, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: … as measured by recovered NIR signals. Then, the computational parameters will be refined through advanced anatomical infant head modeling, and numerical modeling of the path, scattering, and absorption properties of NIR light through infant head tissues. The third… more
Company: ELIA Life Technology, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): ELT proposes to develop an inexpensive printer whose output can be read by touch and sight. The printed output will serve as a bridge to society's graphics rich information - for those who are blind as well as those whohave a fair bit of residual vision and… more
Company: ENDLS OPTICS CORPORATION Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: … therapies. We propose to develop a portable, low power consumption and low-cost, yet accurate and reliable, multimodality optical spectroscopy system with a novel fiber-optic probe to dynamically characterize tumor hypoxia, angiogenesis, and metabolism as well as tissue… more
Company: EY TECHNOLOGIES Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: … thermal and electrical criteria. Not only will the Z-axis laminar composite technology improve thermal and electrical performance, but will also improve fracture toughness quality as well. Flocking technique uses an electric field to propel short fibers onto an adhesive… more
Company: ESPIN TECHNOLOGIES INC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: With tissue engineering science offering promising biomedical interventions for previously untreatable injuries or diseases, many researchers are investigating the use of nanofiber-based medical vehicles for regenerative medicine. The challenge is to produce such vehicles… more
Company: EXEMPLAR GENETICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: … is seen in humans. However, the extended timeframe required for inducing cancer in pigs and the accompanyingphenotypic variability limit their usefulness. Our objective is to create a genetically engineered pig in which tumorigenesis can be conditionally induced in any tissue… more
Company: LUNA INNOVATIONS, INC. Agency/Program/Year/Phase: EPA / SBIR / 2012 / 1
Abstract: … on non-traditional and renewable feedstock need to be developed for both economic and environmental concerns. Bio-oils from biomass such as scrap wood, storm debris and even corn stover can be used to create phenol substitutes useful in the epoxy and wood adhesive markets. … more
Company: LUNA INNOVATIONS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: There is a substantial clinical need in both civilian and battlefield injuries for the repair and regeneration of large-volume-loss skeletal muscle tissue injuries. Current standards of care rely on rotational tissue grafts and often result in substantial morbidity, pain, and… more
Company: Fabrico Technology Inc Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: The majority of battlefield wounds are attributed to soft tissue injuries. Currently NO treatment is available to regenerate large volumes of muscle. To address this need, Fabrico Technology Inc and the University of Texas at Austin proposes to develop a large volume… more
Company: Faraday Technology, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2012 / 2
Abstract: … EPA needs b improving existing processes while utilizing a novel green approach that reduces pollution and improves worker safety. In Phase I, Faraday demonstrated the ability to plate chrome on the interior of cylinders, met the requirements for hardness, adhesion. porosity… more
Company: FIRSTSTRING RESEARCH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: … other corneal abnormalities, which are potentially sight threatening. Currently, therapies to treat these corneal epithelial wounds are very limited. FirstString Research, Inc is an early stage biotech company developing therapeutic peptides for applications in tissue… more
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