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Year:1990
Company: Vertex Pharmaceuticals Inc. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: RECENT REPORTS HAVE INDICATED THAT FK-506, A NOVEL, HIGHLY POTENT IMMUNOSUPPRESSANT, IS AN EFFECTIVE AGENT FOR PREVENTING ORGAN TRANSPLANT REJECTION IN HUMANS THAT DISPLAYS A DIFFERENT TOXICITY PROFILE THAN CYCLOSPORIN A (CSA). A MAJOR FK-506 BINDING PROTEIN, FKBP, HAS BEEN SHOWNTO BE A… more
Company: Vestar, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THIS PROJECT WILL DEVELOP MONOCLONAL ANTIBODY-TARGETED LIPOSOMES FOR THE PURPOSE OF DELIVERING CHEMOTHERAPEUTIC AGENTS. MONOCLONAL ANTIBODY RAISED AGAINST A TUMOR-SPECIFICSURFACE ANTIGEN WILL BE COVALENTLY COUPLED TO THE LIPOSOME SURFACE. THE LINKING CHEMISTRY TO BE USED HAS BEEN DEVELOPED TO SUIT… more
Company: Vestec Corpon Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE GOAL OF THIS RESEARCH IS TO DEVELOP AND ADAPT VESTEC CORPORATION'S "UNIVERSAL INTERFACE" TO COUPLE CONVENTIONAL HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) TO ELECTROSPRAY MASS SPECTROMETRY. THE INTERFACE, WHICH HAS BEEN SUCCESSFULLY APPLIED TO COUPLING REVERSED-PHASE HPLC AT FLOW RATES AS… more
Company: VEXCEL CORP. Agency/Program/Year/Phase: NASA / SBIR / 1990 / 1
Abstract: VEXTRA CORPORATION PROPOSES THE DEVELOPMENT OF A SOFTWARE SYSTEM FOR CONVENIENTLY AND MEANINGFULLY VISUALIZING LARGE MULTI-DIMENSIONAL DATA SETS SUCH AS FROM THE FUTURE HIRIS SENSOR FOR THE EARTH OBSERVING SYSTEM (EOS). THE TECHNIQUESFOR VISUALIZATION WILL INCLUDE VOLUMETRIC RENDERING AND… more
Company: VEXCEL CORP. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: VEXCEL CORPORATION PROPOSES A PHASE I RESEARCH EFFORT FOR THE ANALYSIS AND PRELIMINARY SIMULATION OF A NOVEL METHOD FOR DETECTING HIGH-VOLTAGE POWER LINES AND TOWERS IN UNFRIENDLY REGIONS USING MULTIPLE FLIGHT-PATH SYNTHETIC APERTURE RADAR (SAR) IMAGERY. THE PROPOSED METHOD CONSISTS OF ADAPTING THE… more
Company: Vhg Laboratorys Inc. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: MEASUREMENT OF CRITICAL TRACE LEVEL ELEMENTS IN SEMICONDUCTING MATERIALS MAY BE POSSIBLE USING A SPECIAL ATOMIC ABSORPTION SPECTROPHOTOMETRY TECHNIQUE. DIRECT VAPORIZATION OF SOLID SAMPLES COMBINED WITH A HIGHLY EFFICIENT SYSTEM TO CORRECT FOR NON-ANALYTE ABSORPTION WILL BE INVESTIGATED ON CDTE… more
Company: VIASAT, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: VIA-SAT IS PLEASED TO PRESENT THIS PROPOSAL FOR INVESTIGATION OF THE HARDWARE/SOFTWARE ARCHITECTURE FOR A MULTIMEDIA MULTINETWORK CONTROLLER. THIS PROPOSAL DESCRIBES A PHASE I SBIR PROGRAM TO PERFORM AN EXTENSIVE, REALISTIC, AND THOROUGH INVESTIGATION INTO THE REQUIREMENTS, CAPABILITIES AND… more
Company: VIGYAN, INC. Agency/Program/Year/Phase: NASA / SBIR / 1990 / 2
Abstract: PROOF OF CONCEPT DEMONSTRATION, OF THE 0.3 M TRANSONIC CRYOGENIC WIND TUNNEL IN EARLY 1970'S, HAS PAVED WAY FOR LARGE HIGH REYNOLDS NUMBER CRYOGENIC TUNNEL LIKE THE NATIONAL TRANSONIC FACILITY (NTF) IN 1984. THE QUALITY OF DATA GENERATED IN A CRYOGENIC TUNNEL IS INTIMATELY RELATED TO THE STABILITY… more
Company: VIGYAN, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: COLD FUSION OCCURS WHEN TWO NUCLEI WITH VERY SMALL RELATIVE ENERGY TUNNEL THROUGH THEIR RELATIVE COULOMB BARRIER TO INITIATE A NUCLEAR REACTION. RECENT REPORTS OF COLD-FUSION BETWEEN HYDROGEN ISOTOPES EMBEDDED IN PALLADIUM AND TITANIUM HAVE AROUSED A LOT OF ACTIVITY IN THIS AREA. TO ACHEIVE THE RATE… more
Company: Viro Dynamics Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: ONE OF THE PRIMARY LIMITATIONS IN THE USE OF RADIOIMMUNOSCINTIGRAPHIC TECHNIQUES TO DETECT TUMORS CLINICALLY HAS BEEN THE DIFFICULTY IN ACHIEVING HIGH TUMOR-TO-NORMAL-TISSUE RATIOS OF BOUND RADIOACTIVITY. PART OF THIS DIFFICULTY ARISES FROM THE FACT THAT A SIGNIFICANT PROPORTION OF MONOCLONAL… more
Company: Virolac Industries Agency/Program/Year/Phase: DOE / SBIR / 1990 / 2
Abstract: DILUTED COAL SAMPLES SUBJECTED SIMULTANEOUSLY TO AN OXYGEN TREATMENT AND A LINEAR INCREASE IN TEMPERATURE EVOLVE SULFURDIOXIDE (SO2) INTERMITTENTLY AS A FUNCTION OF TEMPERATURE. DISTINCTIVE SO2 EVOLUTION PATTERNS ARE OBSERVED AMONG COALS OF DIFFERENT RANK AND BETWEEN RAW AND TREATED COALS. THE GOAL… more
Company: VISIDYNE, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: IT IS PROPOSED TO ADD AN INNOVATIVE VARIABLE POLARIZATION OPTICAL SYSTEM TO THE AIR FORCE ABLE (ATMOSPHERIC BACKSCATTER EXPERIMENT) LIDAR SYSTEM. THIS CAPABILITY FOR REAL-TIME, RANGE-RESOLVED POLARIZATION ANALYSIS OF ATMOSPHERIC BACKSCATTER WOULD BE UNIQUE TO THE ABLE LIDAR SYSTEM. IT WOULD ENABLE… more
Company: Vision Sciences Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: VISUAL PERFORMANCE CAN BE IMPROVED WITH PRACTICE. HOWEVER, VISION TRAINING HAS BEEN LIMITED MAINLY TO ORTHOPTISTS AND CERTAIN OPTOMETRISTS. ALTHOUGH VISION TRAINING HAS PRODUCED IMPROVED VISUAL PERFORMANCE IN CERTAIN CASES, THE SCIENTIFIC UNDERSTANDING OF THE VISUAL MECHANISMS BEING TRAINED LAGS FOR… more
Company: Vista Controls Corp. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: THE 155 AUTOLOADER IS A VERY IMPORTANT PART OF THE HIP AND HIP BLOCK IMPROVEMENT PROGRAMS. THIS PROJECT PROPOSES TO INVESTIGATE PREVIOUS, CURRENT AND PROPOSED AUTOLOADERS AND PERFORM A DESIGN TRADE STUDY TO DETERMINE WHAT THE BEST ATTRIBUTES OF EACH. THE TRADE STUDY IS EXPECTED TO PRODUCE TWO… more
Company: Visual Computing Inc Agency/Program/Year/Phase: NASA / SBIR / 1990 / 2
Abstract: THE PROPOSED PROJECT CONCERNS THE DEVELOPMENT OF A 3-D INTERACTIVE GRID PACKAGE. THE NOVEL ASPECTS OF THIS RESEARCH INCLUDE THE DEVELOPMENT OF A UNIVERSAL ALGORITHM FOR GENERATING MULTIPLE-ZONE STRUCTURED AND UNSTRUCTURED GRIDS AND THE DESIGN OF A VISUALLY ORIENTED USER INTERFACE. PHASE I OF THE… more
Company: Vortec Corporation Agency/Program/Year/Phase: DOE / SBIR / 1990 / 2
Abstract: THE PRODUCTION OF INSULATION FIBERGLASS RESULTS IN SUBSTANTIAL QUANTITIES OF WASTE PRODUCTS THAT MUST, IN SOME STATES, BE DISPOSED OF IN HAZARDOUS WASTE LANDFILLS. THE COST OF LANDFILLING THESE MATERIALS AT A SINGLE PLANT OFTEN EXCEEDS $1 MILLION/YR. IN THE END, THE COST OF THIS PRACTICE IS PASSED… more
Company: Vortec Corporation Agency/Program/Year/Phase: EPA / SBIR / 1990 / 2
Abstract: THE PRODUCTION OF INSULATION FIBERGLASS RESULTS IN SUBSTANTIAL QUANTITIES OF WASTE PRODUCTS WHICH MUST BE DISPOSED OF IN HAZARDOUS WASTE LANDFILLS IN SOME STATES. THE COST OF LANDFILLING THESE MATERIALS AT A SINGLE PLANT IS OFTEN IN EXCESS OF $1 MILLION/YEAR WHICH, IN THE END, IS PASSED ON TO THE… more
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