Abstract:THE GOAL OF THIS PROJECT IS TO DEVELOP A RIBONUCLEASE PROTECTION/MISMATCH ASSAY, WHICH WILL ALLOW THE DETECTION OF ESSENTIALLY ALL SINGLE-BASE MUTATIONS. SUCH AN ASSAY WOULD PROVIDE AN INEXPENSIVE AND WIDELY APPLICABLE METHOD FOR SCREENING FOR GENETIC DISEASES, DETECTING MUTATIONS IN ONCOGENES AND… more
Abstract:USING AN ALTO SAXOPHONE WE WILL DESIGN A BRACKET AND A FRAME SYSTEM UPON WHICH WILL BE MOUNTED A SERIES OF ELECTRO-MECHANICAL SOLENOIDS. THE SOLENOIDS WILL BE MOUNTED OVER THE KEYS ON HALF OF THE SAXOPHONE IN ORDER TO BE ABLE TO OPERATE THE KEYS INDIVIDUALLY OR IN GROUPS. THE SOLENOIDS WILL BE… more
Abstract:THE FOLLOWING PROPOSAL COMBINES TWO TECHNICAL INNOVATIONS, A GENERALIZED SINGULAR LINEAR QUADRATIC (GSLQ) ADAPTIVE CONTROL SCHEME AND A CEREBELLAR MODEL ARITHMETIC COMPUTER (CMAC), FOR THE PURPOSE OF ACHIEVING A HIGH PRECISION, ROBUST, ADAPTIVE WEAPON CONTROL SYSTEM DESIGN. THE BENEFITS OF THE… more
Abstract:American GNC Corporation proposes an integrated design approach to the development of advanced target acquisition, identification, engagement, and full fire control prototype. Based on an extensive survey of current methodologies and emerging techniques, the conceptual design proposed in Phase I… more
Abstract:The nonlinearity and unceitainty inherent in the HAVE DASH II missile's dynamics have been a great challenge to the autopilot design that is required to have satisfactory performance for all flight conditions in probable engagements. Several advanced robust nonlinear approaches, namely,… more
Abstract:The integrated automatic target recognition (ATR) design provides a promising approach to achieving high performance based on multisensor data fusion, processing methodology integration, and target/enviromental/contextual information incorporation. In this proposal, American GNC Corp. (AGNC) will… more
Abstract:The integrated fire control/weapon system design is an important part of the general effort in integrated avionics, flight control, fire control, and weapon systems design to improve weapon effectiveness and aircraft survivability. The delivery accuracy can be improved through reducing the effects… more
Abstract:Advanced rotorcraft systems are highly complicated and have become prime targets for enemy anti-air weapons. Thus, battle-induced damage can be anticipated. To increase the availability, combat survivability, maintainability, and life-cycle cost effectiveness of advanced rotorcraft, reconfigurable… more
Abstract:RECENT DEVELOPMENTS IN INTERNATIONAL RELATIONS HAVE LED TO THE NECESSITY FOR BATTLE READINESS IN A REGION WHERE CHEMICAL OR BIOLOGICAL WARFARE AGENTS HAVE BEEN EMPLOYED IN THE PAST. AT PRESENT, LITTLE ATTENTION HAS BEEN PAID TO METHODS FOR IDENTIFYING THE CHEMICAL OR BIOLOGICAL CONDITIONS OF FREE… more
Abstract:ONE OF THE MAJOR OBSTACLES TO EDUCATION AND EMPLOYMENT OF INDIVIDUALS WITH SEVERE VISUAL DISABILITIES IS THE INABILITY TO ACCESS VISUAL IMAGES FOUND IN THE EDUCATIONAL SETTING OR REQUIRED FOR SATISFACTORY PERFORMANCE IN THE WORKPLACE. EFFORTS TO PROVIDE ACCESS TO VISUAL IMAGES HAVE INCLUDED… more
Abstract:THE RAPID INCREASE IN WORLD SEAFOOD PRODUCTION BY AQUACULTURAL PROCESSES HAS PLACED A COMPETITIVE BURDEN ON THE UNITED STATES FISHING AND FISH FARMING INDUSTRIES. ECONOMIC PRESSURES HAVE DICTATED THE DEVELOPMENT OF HIGH DENSITY CLOSED-CYCLE AQUACULTURE (HDCCA) UNIT OPERATIONS TO PROVIDE SEAFOOD… more
Abstract:Subsurface corrosion has been implicated in a number of incidents in which aircraft have demonstrated a loss of structural integrity leading to emergency procedures and in one case, the loss of human life. Although several techniques are available to evaluate subsurface corrosion, no method has… more
Abstract:The Air Force has identified a need for more advanced digital control methodologies to make feasible the application of active magnetic bearings to turbine engines. Achieving the goals for enhanced turbine rotor performance necessitates improved bearing control with associated compact size/weight,… more
Abstract:The use of high-temperature laser densification/annealing techniques for enhancing materials surface characteristics has opened new opportunities in material/laser-process diagnostic instrumentation. Important issues in fabrication of reproducible refractory ceramic coating film lies in… more
Abstract:FIBER-OPTIC SENSORS, IN CONJUNCTION WITH FLUORESCENCE SPECTROSCOPY, HAS MANY USES IN BIOCHEMISTRY, IMMUNOASSAYS, AND CLOSED-AQUACULTURE SYSTEMS. THE USE OF IN SITU FLUORESCENCE MEASUREMENT DURING FIELD TESTS IS HAMPERED BY THE PHYSICAL LIMITATIONS OF SPECTROMETERS RELATED TO THEIR SIZE, WEIGHT, AND… more
Abstract:NIAAA has identified the need for education materials which facilitate the training of health professionals and paraprofessionals in the use of various alcoholism assessment techniques and instruments. In response to this need, we will develop a icon-based courseware for alcoholism appraisal… more
Abstract:The objective of this contract is to develop monitoring technology to accurately screen patients on an outpatient basis by monitoring physiologic variables capable of indicating whether or not there is a need for future, more costly, sleep disorder testing. The Contractor shall perform the following… more
Abstract:The National Institute of Child Health and Human Development has identified the need for programs to delay the onset of sexual activity among adolescents and to increase contraceptive protection of the adolescents who are sexually active. In response to this need, we will develop a hypermedia-based… more
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