Abstract:THE IUSS HAS AN URGENT NEED FOR MORE EFFICIENT METHODS OF SIGNAL PROCSSSING. TO MEET THIS END, SUBMARINE DETECTION AND CLASSIFICATION SYSTEMS MUST BE REEXAMINED AND MODIFIED. THIS PROPOSAL EXAMINES THE POTENTIAL OF AN INNOVATIVE TECHNIQUE CALLED FRACTAL IMAGE ANALYSIS TOAID OPERATORS TO ACCURATELY… more
Abstract:MOUTHSTICKS OR ORTHODONTIC ORTHOSES ARE WIDELY USED BY PEOPLE WITH SPINAL CHORD INJURIES OR SIMILAR DISABILITIES TO INCREASE CONTROL OVER THEIR ENVIRONMENT. PEOPLE WITH THE ADDITIONAL LIMITATION OF LITTLE OR NO ANTERIOR/POSTERIOR HEAD MOTION MAY BENEFIT FROM AN EXTENDIBLE MOUTHSTICK. HOWEVER,… more
Abstract:The proposed Phase I work will constitute a study of prospective organic dye host materials, fabrication techniques, AR/HR/PR (Anti-Reflection/High Reflection/Partial Reflection) optical coatings (specific to the selected host material), and factors which are relevant to optical pumping with… more
Abstract:AN INNOVATIVE ADVANCEMENT IN SCANNING IMPULSE RADAR ARRAY TECHNOLOGY OFFERS A NEW CAPABILITY TO DETECT BURIED METALLIC AND NONMETALLIC MINES. THE SCANNING IMPULSE RADAR ARRAY SYSTEM WILL INCORPORATE ACTIVE CANCELLATION AND POLARIZATION CONTROL TO ENHANCE THE MINE-SOIL INTERFACE TO PERMIT DETECTION.… more
Abstract:A low-cost radar fuze is proposed based on an innovative impuse-generated Ultra-Wideband (UWB) source developed by ANRO Engineering, Inc. (ANRO) under IR&D Funds. The new source offers simplicity of design and implementation, and inherent jam resistance and low probability of intercept properties.… more
Abstract:WE PROPOSE AN EFFICIENT AND COST-EFFECTIVE QUERY PROCESSING COMPONENT FOR AN INFORMATION RETRIEVAL SYSTEM BASED ON THE USE OF NETWORKED MICROCOMPUTERS AS A LOOSELY-COUPLED NETWORK DATABASE. THE QUERY PROCESSSING SYSTEM WILL WORK ON BOTH LOCAL AND WIDE AREA NETWORKS AND CAN BE USED WITH ANY METHOD OF… more
Abstract:Taxol is a promising new cancer agent. We will determine whether phosphonium-ion conjugates of taxol would be more effective in a patient-like animal model. It has recently been demonstrated that taxol inhibits the metastatic spread of a PC-3 human prostate tumor cell subline in a SCID (severe… more
Abstract:We are developing a new tumor selective treatment termed antimethionine chemotherapy. Many tumor types have been shown to exhibit an absolute requirement for methionine in vitro in order to proliferate. Normal cells and tissues can utilize homocysteine in place of methionine in order to proliferate.… more
Abstract:We propose to demonstrate the feasibility of fabricating a phototransistor using the A1xGa1-xN material system. The proposed phototransitor is based on a GaN-A1xGa1-xN heterojunction which exhibits a 2-D electron gas conduction when a bias is applied on the source-drain terminals. The device is… more
Abstract:The use of cryogenic solid hydrogen as a rocket propellant may lead to major advances in rocket propulsion. To use solid hydrogen as a propellant requires a system designed to solidfy, store, and transport hydrogen. We propose to study different methods for creating H2 for more than one hour at… more
Abstract:Recent studies have shown that light has surprising neuroendocrine and anti-depressant effects in humans. Prompted by these findings, a UCSD group has three times replicated a 1967 study by Dewan showing that an ordinary bedside light can influence menstrual cyclicity. Before we can even begin to… more
Abstract:THE GOAL OF THIS PROJECT IS TO DEVELOP AN ARRAY OF 10-(4)CM(2) ELECTRODES FOR USE WITH A NEW INSTRUMENTAL METHOD FOR TISSUE CULTURE. THE METHOD, REFERRED TO AS ECIS (ELECTRIC CELL-SUBSTRATE IMPEDANCE SENSOR), IS A NON-INVASIVE TECHNIQUE TO MEASURE SEVERAL IN VITRO CELL PARAMETERS THAT HAVE… more
Abstract:There is a significant demand for inexpensive activated or activable gels for the coupling of antibodies and other ligands to use in affinity chromatography, industrially as well as on a laboratory scale. We will develop and optimize novel gels based on natural polymers that can be employed for this… more
Abstract:RECENTLY DEVELOPED MOLECULAR TECHNIQUES WILL BE USED TO ANALYZE MUTATIONS AT THE TK LOCUS IN MOUSE L5178Y CELLS EXPOSED TO CHEMICAL MUTAGENS. BECAUSE MUTATION ASSAYS MEASURE PHENOTYPE, NOT GENOTYPE, SCORED MUTATIONS COULD RESULT FROM OTHER MECHANISMS. SEQUENCE ANALYSIS WILL DETERMINE WHETHER THE… more
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