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Year:2001
Company: ANTAKAMATICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: The safety and efficacy of a prosthetic cardiovascular device critically depends on competing hemodynamic factors governing blood trauma and thrombosis. Unlike the aerospace industry which uses advanced design methods such as computational fluid dynamics (CFD) to optimize aerodynamics, the medical… more
Company: ANTAKAMATICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Verbatim From Applicant's Abstract): As the prospects of a
mechanical replacement for a failing human heart are fast becoming a reality,
and patients are indeed returning home to regain a "normal" lifestyle, the
limitations of this technology upon quality… more
Company: ANTEX BIOLOGOCIS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Antex biologics is developing inactivated whole cell vaccines for oral delivery to prevent infections by bacteria causing traveler's diarrhea. A new, possibly breakthrough, microbead formulation technology is being developed which should be evaluated forits potential to enhance these inactivated… more
Company: ANTIGEN EXPRESS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION: Suppressing the Ii protein by anti-sense oligonucleotides in MHC
class Il-positive cancer cells creates a potent cancer cell vaccine.
Presumably, additional determinants which are normally excluded in the ER by
the Ii protein from the MHC class II… more
Company: ANTIGEN EXPRESS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION: Antigen Express has developed technology to force the presentation
of endogenous tumor antigens in a manner that produces an effective tumor cell
vaccine. The key to this strategy is the generation of tumor cells that express
MHC Class II molecules in the absence of the… more
Company: ANTIGENICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2001 / 1
Abstract: DESCRIPTION: (Adapted from Applicant's Abstract) Malaria is a disease which
affects more than 300 million people each year and is fatal for 1.5 million.
The overall objective of this STTR Phase I project is to produce a cGMP malaria
vaccine consisting of the 42 kDa C-terminal… more
Company: Anvik Corporation Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Compound semiconductors enable numerous important electronics and optoelectronics applications. They are commonly produced via epitaxial deposition methods, but the existing compound semiconductor substrate materials are expensive, highly defective, andnot available in large sizes. The use of… more
Company: Anvik Corporation Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Recent developments in DNA microarray generation technology have made entirely new methods of gene analysis feasible. The DNA microarray can greatly facilitate research in the areas of drug and vaccine discovery, disease screening, and toxicology, amongothers. Therefore, the importance of a… more
Company: Anvik Corporation Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Thin-film transistor (TFT) technology has enabled important applications, such as flat-panel displays (FPDs), that cannot be addressed by conventional silicon-wafer-based electronics. There are several benefits to fabricating TFTs on flexible substrates,including lower cost, increased versatility,… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant):The goal of this proposal is to establish
the value of the 3' noncoding region (NTR) of hepatitis C virus ((HCV genome as
an amplification target in a viral load assay. HCV is the most prevalent
chronic bloodborne infection in the U.S.… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2001 / 2
Abstract: DESCRIPTION (provided by applicant):The goal of this proposal is to establish
the value of the 3' noncoding region (NTR) of hepatitis C virus ((HCV genome as
an amplification target in a viral load assay. HCV is the most prevalent
chronic bloodborne infection in the U.S.… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant): Identification of a well-defined and
robust cell-culture system for hepatitis C virus (HCV) is critical for
facilitating efforts to identify antivirals against HCV. Apath, LLC proposes to
develop a series of cell-based assays for… more
Company: APERIO TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant): Manual slide scanning is one of the most
tedious and time-consuming elements of cytogenetic analysis. The development
and application of a new automated digital scanning technology, termed
ScanScope, is proposed for efficiently… more
Company: APES, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: The multi-task objectives of the plan discussed in this proposal are: research the role and effects of fretting on structural life of components, develop and demonstrate the feasibility of integrating candidate fretting fatigue predictive analytic model(s)into structural integrity methods, integrate… more
Company: Apex Systems, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: Mobile Geographical Information Systems (MOGIS) are applications capableof running on wireless devices. Two major hardware limitations havehindered the development of efficient MOGIS: (1) reduced screen sizesand (2) small memory capacities. An innovative approach that overcomesthese shortcomings is… more
Company: Apex Systems, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project describes an innovative approach to automating the integration of geographical data from multiple resources. This process is commonly referred to as conflation. The most important aspect of the conflation process is feature matching.… more
Company: APOGEE ENGINEERING, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Apogee Engineering Inc. proposes to R&D a unique process for dehydrating a slurry of10% pelletized nitrocellulose (PNC) in water, ending with a final product of 60% PNCin a n-heptane slurry with a maximum of 0.1% water. The existing process involvesdrying the PNC to dryness in ovens and handling… more
Company: APOGEE ENGINEERING, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Apogee Engineering Inc. proposes to R&D a system for separating partially empty aerosol cans into: empty cans, plastic parts, residual liquid and volatile components.The approved disposal method is collection in steel drums, where one drum full of 150cansis a drum of Excess Hazardous Waste for… more
Company: Apogee Scientific, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2001 / 1
Abstract: Mercury from combustion sources is a major concern to the nation's air quality. In December 2000, EPA announced that it would regulate mercury emissions from coal-fired boilers under Title III of the Clean Air Act Amendments of 1990. EPA plans to issue final regulations by December 2004, and is… more
Company: Apogee Scientific, Inc. Agency/Program/Year/Phase: EPA / SBIR / 2001 / 2
Abstract: Mercury from combustion sources is a major concern to the nation's air quality. In December 2000, EPA announced that it would regulate mercury emissions from coal-fired boilers under Title III of the Clean Air Act Amendments of 1990. EPA plans to issue final regulations by December 2004, and is… more
Company: APOLLO INSTRUMENTS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: We propose to develop a general method for the high brightness fiber-coupied laser diode system. The overall goal of this program is to deliver a brightness of 1.4 Mega Watt cm-2 sr-1 laser power system from a single fiber with a high power ourput. Thepackage will have high power density, compact… more
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