Abstract:DESCRIPTION (provided by applicant): Ty800 is a live attenuated Salmonella typhi organism intended to be used as a prophylactic single dose oral vaccine for Typhoid fever. Ty800 may have advantages in several respects to current Typhoid fever vaccines, and consequently could be a significant advance… more
Abstract:DESCRIPTION (provided by applicant):
Our goal is to develop 1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP) as a clinical inhibitor of ceremide catabolism, in order to enhance the anti-cancer activity of the cytotoxic retinoid, fenretinide (4-HPR). We have reported that 4-HPR increased… more
Abstract:The objective of this proposal is to design a metalanguage-formatted distributed database architecture as outlined in MDA SBIR topic MDA03-043. Avanza has already completed Phase I development of a secure data repository project called SecureCommunication Object Repository Environment (SCORE) that… more
Abstract:73155S03-I Superconducting particle accelerators require high power radio frequency (RF) couplers that have high capital and operational costs. The operational costs include power dissipation at cryogenic temperatures and operational down time. New coupler designs are needed to reduce these costs… more
Abstract:73156S03- I Superconducting Radio Frequency (SRF) cavities are a critical device for present and future particle accelerators in military, research, and industrial applications. The performance of these cavities is limited by field emission, which is controlled by cavity processing techniques. … more
Abstract:Hybrid electric vehicles, in contrast to electric vehicles, require a storage battery that is capable of fast charge/discharge rates in addition to a high storage capacity. AVEKA, Inc. has formulated an amorphous form of vanadium pentoxide that surpassesthe performance of its crystalline form at… more
Abstract:DESCRIPTION (provided by applicant):
Prostate cancer is the second leading cause of cancer death in US men. Prostate cancer is highly dependent on androgen stimulation mediated through the androgen receptor (AR) for growth and proliferation. For those with advanced PCa, androgen ablation remains… more
Abstract:DESCRIPTION (provided by applicant): The broad, long-term objectives of the application are to develop antisense inhibitors of retinopathy and document their mechanism(s) of action. Retinopathy is a significant cause of eye disease and has a major impact on development, learning, communicating,… more
Abstract:DESCRIPTION (provided by applicant): With a daily production capacity of two grams of protein per egg, the chicken ovalbumin gene locus has the potential to synthesize large amounts of biopharmaceutical proteins into the eggs of transgenic hens. This phase I SBIR project will test the feasibility of… more
Abstract:Avineon proposes to develop an intelligence gathering system to identify and monitor the knowledge gained from the integration of system interoperability management data (Risk analysis, BF Comparisons, Metrics, DMSAR, Program TRs, BF CM data, BF ECManalysis) with mission analysis, system models,… more
Abstract:Avineon proposes to develop a model for acquiring, organizing, storing, distributing, and analyzing the combat systems data resulting from interoperability tests, corrective actions, upgrades and modifications, during the D-30 process. The analyses will:(1) assist in the determination of readiness,… more
Abstract:A new hand-held, lightweight, low-cost, modular, infrared remote sensor of chemical weapon agents (CWA) and toxic industrial chemicals (TIC) will be developed for anti-terrorism applications. The sensor will depend on new differential absorptionradiometer (DAR) technology that enables detection of… more
Abstract:We will first conduct aircraft vulnerability simulations and analysis of commercial aircraft and identify the least vulnerable/critical fuselage areas. Then continue the simulation and analysis with various increasing levels of IR radiation at these areasof interest to assess missile hit or approach… more
Abstract:We are proposing to develop unique and innovative Passive Missile Warning signature processing algorithms to meet threat identificationneeds and optimize IRCM protection for today's military and civilian aircraft from the early generation AND today's advanced IR missilethreats. Our missile… more
Abstract:Today's military aircraft require protection against a new generation of laser beamrider (LBR) threats that are more capable and difficult to defeat. In many cases, high levels of disruptive Optical Countermeasures (OCM) jamming energy must be directed atthe LBR operator to temporarily dazzle his… more
Abstract:The Air Force and other DoD agencies are seeking transformational communications and technology that will support legacy and future mission data transfers over lower-cost and more reliable network infrastructure, such as Internet Protocol (IP) networks.In Phase I, Avtec will (1) define the… more
Abstract:In Phase II, the focus is select real world scenarios to demonstrate an actual implementation and to evaluate the performance of the proposed dynamic networking. Avtec will focus on the following Time Sensitive/Time Critical wide bandwidth applications:Link 16 Enhanced RELNAV Targeting in GPS… more
Abstract:In Phase II, the focus is select real world scenarios to demonstrate an actual implementation and to evaluate the performance of the proposed dynamic networking. Avtec will focus on the following Time Sensitive/Time Critical wide bandwidth applications:Link 16 Enhanced RELNAV Targeting in GPS… more
Abstract:Avtec views this SOCOM program as an RF systems development program, more than just an antenna development program. The family of antennas developed under this program must work with a wide range of communications systems, and also provide a wide range offunctionality (communications reception and… more
Abstract:In Phase I, we plan to demonstrate the feasibility of our approach to develop a dual wave band VLWIR HgCdTe focal plane array technology via demonstration of dual color VLWIR detectors with minimal crosstalk and high performance ion both the VLWIR colorsApplications in geophysics, geology, and… more
Abstract:In Phase I, we plan to demonstrate the feasibility of elements of our approach to develop a technology to fabricate SWIR HgCdTe detectors with higher yield and higher performance at lower costs. Phase II will focus on optimizing the approach for largearrays, in a production set up. industrial and… more
Abstract:In Phase I, AVYD DEVICES in collaboration with SRI International, will demonstrate the feasibility of our modeling approach to predict material properties and device performances using experimental parameters of growth and fabrication processes formulticolor HgCdTe detectors. The models will… more
Abstract:DESCRIPTION: This R25/R44 proposal aims to develop a browser-based interactive product to educate both physicians and patients about banking sperm before cancer treatment. The product will have three components: 1) a didactic portion to update oncology physicians on the rationale to offer… more
Abstract:DESCRIPTION: This R25/R44 proposal aims to develop a browser-based interactive product to educate both physicians and patients about banking sperm before cancer treatment. The product will have three components: 1) a didactic portion to update oncology physicians on the rationale to offer… more
Abstract:We plan to develop and refine a device (Basic Life Support System, BLSS) and a just-in-time training procedure for a flight crewmember who must administer cardio pulmonary resuscitation (CPR). In Phase I, we developed a computerized graphical display for CPR procedures. Volunteers using the display… more
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