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Year:2004
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Displaying 451 – 475 of 7083 Awards
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): An ultra-compact, high-performance, multi-laser, many-parameter, bandwidth-selective flow cytometer is the expected result of the research and development proposed here. The cellular analysis typically carried out by a device of this type, through the use of… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 2
Abstract: 73066-For several decades, photo-multiplier tubes (PMT) have been the key technology for sensing light in most high energy physics research operations. Although extraordinarily successful, PMT technology has a number of limitations: large PMTs cannot be mass produced, they cannot operate under… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Nuclear medicine imaging modalities such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) are powerful, non-invasive medical imaging techniques that provide an image of the three dimensional distribution of a… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): The y-ray scintillation camera is the instrument of choice for imaging static and dynamic radioisotope distributions in vivo and provides information about functionality, morphology, and metabolic activity that is critically needed for medical diagnosis and… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: New technology is needed for the nondestructive detection and characterization of defects in aerospace structures, particularly those with compex shapes that are used in high stress environments that accelerate degradation. Existing nondestructive evaluation (NDE) techniques, based on ultrasonics,… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2004 / 2
Abstract: CCDs (Charge-Coupled Devices), and more recently, CMOS (complementary-symmetry metal-oxide-semiconductor) APS (Active Pixel Sensor) cameras have revolutionized imaging instrumentation and the many fields that utilize these instruments. Both these technologies rely on integrating, the analog… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2004 / 1
Abstract: Field inspection of printed circuit boards (PCB), and assessment of their condition is critical for the readiness of military equipment. A new technology is needed that is portable and able to inspect PCBs, yet can perform sophisticated characterization of defects, and predict the remaining life of… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75530-Positron emission tomography (PET) is a powerful imaging tool that can provide diagnosis for symptoms of diseases such as cancer, Alzheimer's disease, head trauma and stroke. However, the performance of current clinical PET systems is limited by available detector technology, and there is an… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75096-Despite excellent scintillator properties and its use in a wide variety of applications, CsI(Tl) has not been used for radionuclide imaging in medical applications. The primary reason is the presence of a strong afterglow component in its scintillation decay, which reduces the energy… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75170-X-ray detectors with high energy resolution, high sensitivity, and high count-rate performance are required in electron beam systems for materials science research. In many X-ray detection studies conducted with electron beam systems, system performance is limited by the characteristics of… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75438-With the ever-increasing number of human diseases being modeled in small animals such as mice and rats, the high resolution radionuclide imaging (such as SPECT, single photon emission computed tomography) of these small animals is required. Clinical SPECT scanners used for human imaging are… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 76325-Gamma ray spectrometers are an important tool in the characterization of radioactive waste, such as found at many DOE sites. These gamma ray spectrometers require good energy resolution, high detection efficiency, compact size, light weight, portability, and low power requirements. No… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75745-Neutron beam facilities, used for materials research studies, require high neutron fluxes, but their utilization is often limited by detection systems that use scintillators. None of these scintillators exhibit good neutron detection and energy resolution, fast response, and high light yield… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2004 / 2
Abstract: This Phase II SBIR describes the fabrication and characterization of a position sensitive detector with internal gain. Phase I research demonstrated the fabrication of several position sensitive avalanche photodiodes (APDs), including quadrant and lateral-effect photodiodes. With position resolution… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOD / STTR / 2004 / 1
Abstract: The pervasiveness of nanoparticles and nanomaterials is rapidly expanding, and determination of their chemical composition can be achieved by Laser-Induced Breakdown Spectroscopy (LIBS) excited through an optical fiber of nanometer dimensions. We propose to develop a LIBS system for nanomaterials… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The focus of the application is in the area of breast cancer imaging and tumor characterization. Imaging in pre-clinical models with injected contrast agents and imaging the oxygen concentration within tissue are important for a number of clinical and… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75524-Single photon emission computed tomography (SPECT) maintains an important role in the study of disease models in small animals as well as in patient care. Although rich in physiological information content, interpretation of SPECT data for these studies is challenging because SPECT images… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a nuclear imaging modality that makes use of a range of positron-emitting tracers to provide images that reflect different parameters relevant to tumor biology. Tumor cells generally differ from normal cells in many… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2004 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project is to investigate a new, high performance scintillation detector for eventual use in nuclear borehole logging. Nuclear borehole logging is an important technique for both geophysical research and commercial oil exploration. Well logging… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): CsI doped with thallium is one of the most important scintillators currently in use. In terms of conversion of ionizing radiation to visible photons, it is the unquestioned leader in efficiency. Additionally, its high density, high atomic number, excellent light… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75416-The performance of nuclear physics detection systems is often limited by the properties of the scintillators that are presently available for neutron and gamma ray detection. This project will develop a new scintillator material that provides excellent light yield for neutrons and also… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): CsI doped with thallium is one of the most important scintillators currently in use. In terms of conversion of ionizing radiation to visible photons, it is the unquestioned leader in efficiency. Additionally, its high density, high atomic number, excellent light… more
Company: ALERION BIOMEDICAL, INC. Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase I STTR project is to design, synthesize, and test a new class of biochemically activated magnetic resonance imaging (MRI) contrast agents to detect and monitor enzymatic activity in vivo. The proposal responds to the Program Announcement… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Many patients in the later stages of Parkinson's disease experience periods of acute immobility ("off' periods) that substantially decrease their quality of life. The most effective pharmacological treatments for these acute "off' periods are dopamine agonist… more
Company: Alexza Molecular Delivery Corporation Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Despite the severe health consequences of smoking and the desire of most smokers to quit, tens of millions of Americans continue to smoke. This in part reflects the poor efficacy of existing smoking cessation therapies, which result in sustained abstinence in a… more
Displaying 451 – 475 of 7083 Awards
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