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Year:2004
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Displaying 551 – 575 of 7083 Awards
Company: Alternative Energy Solutions, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2004 / 2
Abstract: The purpose of this project is to continue developing tools to match existing Computer Assisted Design (CAD) software to Geant4 with a special view to shielding simulations for NASA. Geant4 is a particle transport and interaction simulation toolkit,originally developed to help with Monte Carlo… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOD / STTR / 2004 / 2
Abstract: Bulk fuel desulfurization is required to apply fuel cells to a new class of naval vessels. Altex, a small business entity, and Pennsylvania State University (PSU), a research organization, have teamed up under a Phase I STTR program and have shown the feasibility of the innovative Logistic Fuel… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOD / SBIR / 2004 / 2
Abstract: To effectively use fuel cells in military and commercial applications, diesel fuel and JP-8 need to be reformed in a reliable and highly efficient reformer. Altex Technologies Corporation (Altex) and Pennsylvania State University (PSU) have identified the Compact and Efficient Logistic Fuel (CELF)… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOD / SBIR / 2004 / 1
Abstract: To effectively use fuel cells in military and commercial applications, diesel fuel and JP-8 need to be reformed in a compact, reliable and highly efficient reformer. Altex Technologies Corporation (Altex) and Pennsylvania State University (PSU) have identified the Compact and Efficient Logistic Fuel… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75580-Conventional hot water heat exchangers, which utilize waste heat from micro-turbines, are large, heavy, and costly, limiting the application of micro-turbine-based Combined Heat and Power systems to institutional, commercial, and residential markets. This project will develop a compact heat… more
Company: ALTHEA TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant) In the area of cancer, microarray analysis is being used to identify specific differences between normal and disease tissues. Such efforts are leading to the identification of small gene sets, or signatures, that can provide key information for classifying… more
Company: ALTHEA TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this proposal is to provide a pathway for translating microarray-based research in cancer and toxicology into cost efficient, high throughput, validated assays for the assessment of a range of different toxicological and oncological… more
Company: X Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of these studies is to further pre-clinical development of a soluble three-domain single chain T-cell receptor IL-2 fusion protein (264scTCR/IL-2). This T-cell receptor, which recognizes an unmutated peptide epitope of the human tumor suppressor… more
Company: X Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this research is to demonstrate proof-of-principle for using a T-cell receptor (TCR)-based fusion protein as a staining reagent for human tumors. The TCR portion of this fusion protein is specific for an unmutated p53 peptide presented in the context… more
Company: ALTRUE.COM, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): This proposal intends to test the use of open source software technologies to fulfill the critical need of academic and small- to medium sized private research laboratories for a robust yet cost effective solution to their ever-growing data management,… more
Company: Altuda Energy Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 72494-This project will use microbiological bioconversion technology in situ to convert sequestered greenhouse gases, including carbon dioxide and carbon monoxide, into methane and other useful organic compounds. Indigenous anaerobic bacteria will be added to coal along with supplemental nutrients… more
Company: Altuda Energy Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 2
Abstract: 72494-This project will use microbiological bioconversion technology in situ to convert sequestered greenhouse gases, including carbon dioxide and carbon monoxide, into methane and other useful organic compounds. Indigenous anaerobic bacteria will be added to coal along with supplemental nutrients… more
Company: Altuda Energy Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 72593-Methane has a global warming potential 21 times greater than carbon dioxide and a much shorter half-life in the atmosphere. Therefore, on a ton-by-ton basis, technology that targets methane emissions would mitigate global warming at a faster rate than the reduction of carbon dioxide emissions… more
Company: Altuda Energy Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 2
Abstract: 72593-Methane has a global warming potential 21 times greater than carbon dioxide and a much shorter half-life in the atmosphere. Therefore, on a ton-by-ton basis, technology that targets methane emissions would mitigate global warming at a faster rate than the reduction of carbon dioxide emissions… more
Company: ALVEOLI MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The benefits of Tracheal Gas Insufflation (TGI) as an adjunct to mechanical ventilation are well known. 1 TGI reduces dead space and CO2 rebreathing in mechanically ventilated patients, thereby reducing PaCO2 with no change in minute ventilation, or maintaining… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Breast cancer is the most common malignancy, which occurs in women and the 2nd leading cause of cancer death. While the majority of breast cancers are sporadic (not inherited), approximately 10 percent are due to inherited mutations in the BRCA1 and BRCA2… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Proteomics is set to have a profound impact on disease diagnosis, treatment and monitoring. Protein expression profiling is one of the important parameters that can be monitored in the course of neoplastic disease. While several fast and efficient proteomic tools… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): There are approximately one million persons in the U.S. infected with HIV-1, with 40,000 new cases reported each year. While most of these patients greatly benefit from highly active antiretroviral therapy (HAART), they often develop multi-drug resistance… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The human genome has opened a new chapter for drug discovery. In contrast to conventional drug discovery methods, which screen a drug library against a single protein target, the entire protein complement of the genome, i.e. the proteome, is now available for… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): The human genome has opened a new chapter for drug discovery. In contrast to conventional drug discovery methods, which screen a drug library against a single protein target, the entire protein complement of the genome, i.e. the proteome, is now available for… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The main goal of this project is to develop a microarray based system for comprehensive health assessment of laboratory animals. This microarray based test would be capable of simultaneous testing for the presence of all relevant pathogens and would require only… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): In the past several years, a significant need has arisen to analyze bacterial gene expression following interactions with host cells in vivo. In vivo whole genome expression analyses are seen as crucial for identifying novel bacterial targets for therapeutic… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): MicroRNAs are small, 19-25mer RNAs that are encoded in the genomes of upper eukaryotes. MicroRNAs appear to regulate global gene expression by modulating the translation of mRNAs transcribed from key genes. Although the research field is still young, microRNAs… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The overall objective of this proposal is to develop methods for the cost-effective, large-scale synthesis (up to kilograms amounts) of capped RNA. Companies such as Wyeth Vaccines, AlphaVax and Merix Biosciences are using capped RNA to produce human vaccines… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal is to develop a robust procedure for extracting RNA from tissues that have been fixed in formaldehyde, either neutral buffered formalin or buffered paraformaldehyde. Clinically interesting tissue from biopsies and necropsies is routinely archived… more
Displaying 551 – 575 of 7083 Awards
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