Abstract:DESCRIPTION (provided by applicant): Microarrays are powerful tools that can impact new diagnostic procedures and expedite the drug development process. A significant but largely unrealized application is gene expression analysis from RNAlimited samples, such as blood, needle biopsies, laser capture… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this proposal is to develop rapid, high-throughput methods to quantify the levels of small RNA molecules such as small-interfering RNAs (siRNAs) and microRNAs (miRNAs) in biological samples. Pharmaceutical and biotechnology companies are… more
Abstract:AMBPTech in collaboration with Dr Wayne Anderson's group at SUNY Buffalo proposes to develop a technology for manufacturing high performance GaN transistors on roll to roll flexible non-conducting foils. This effort will transfer the leading research done at the University of Buffalo in the area… more
Abstract:The proposed program by AMBP Tech and Professor Sarjeant's group at SUNY Buffalo will develop and demonstrate a rapid large area deposition process of high energy density amorphous fluorinated carbon (a-C:F) films onto thin aluminum (4um thin) electrode substrates. The innovative research consists… more
Abstract:DESCRIPTION (provided by applicant): A novel and promising approach for achieving bony repair especially for large bone defects is to transplant human bone marrow stromal cells or mesenchymal stem cells (hMSCs). Culture expanded hMSCs, transplanted into immuno-compromised recipient mice on porous… more
Abstract:DESCRIPTION (provided by applicant): Spinal disc herniation and the resulting symptoms of intractable pain, weakness, sensory loss, incontinence and progressive arthritis are among the most common debilitating conditions back problems. When conservative treatment fails, and diagnostic imaging… more
Abstract:The objective of the Phase II project is to develop a generic multi-agent high-performance real-time decision aid system, in which multi-agent tracking, communication, hybrid system modeling, information fusion and decision aid components can be easily integrated with ARDEC's CDAS (Combat Decision… more
Abstract:This Phase II project is aimed at developing an automatic, imagery based, processing software that allows extraction from and placement of culture features (such as, buildings) in images of a database. Object classification is effected through features based on edges and intensity distribution.… more
Abstract:The objective of this Phase I project is to design a micro inertial stabilization mechanism with embedded microelectromechanical system (MEMS) sensors, for laser pointing and stabilization. The stabilization mechanism design is based on AGNC-developed MEMS gyro technology and integrates the… more
Abstract:This project develops an adaptive data fusion and analysis system to intelligently process, analyze, combine, and abstract useful knowledge from heterogeneous test data sources aboard aircraft/ship by integrating evidence theory, fuzzy logic, plausible reasoning, and dynamic probabilistic networks.… more
Abstract:The purpose of this project is to develop an innovative plug and fight architecture to support the high speed information exchange between various shipboard command, control and communication subsystems. The structure of this system is based on a very high speed Wireless Local Area Network (Wireless… more
Abstract:Accurate absolute position, velocity, attitude and precise relative navigation are critical capabilities for unmanned air vehicles (UAVs) to improve their autonomy and reduce the mission life-cycle cost. This Phase I project investigates a low cost, miniature reconfigurable autonomous navigation… more
Abstract:The main goal of this Phase I SBIR proposal is to demonstrate the feasibility of developing an automated method that can be used in the field to identify and quantify polychlorinated biphenyl compounds (PCBs) present in solid materials felt gasket, faying material, paint, electric power cable… more
Abstract:75471-Measurement techniques are needed to validate technologies developed to assure the long-term sequestration of carbon in man-made and natural environments. In particular, a capability is required to determine increases in carbon fixation or sequestration of 1 tonne per hectare per year. This… more
Abstract:75470-The sequestration of carbon is a major world-wide goal for reducing the greenhouse effect. New, low cost methods are needed for determining and verifying carbon sequestration and for lowering its overall cost. Existing biomass and carbon survey methods and technologies are too slow, too… more
Abstract:DESCRIPTION (provided by applicant): Pain is a serious, debilitating condition that is under-treated because of the dose-limiting side effects of currently used opiate drugs such as morphine. Enkephalin is an endogenous opiate peptide, which induces analgesia, but unlike morphine it has few, if any… more
Abstract:The objective of this proposal is to demonstrate the feasibility of a novel, low-cost corrosion inhibiting material that self activates when exposed to moisture and is compatible with common manufacturing process. The primary goal is to enhance corrosion inhibition techniques at the manufacturing… more
Abstract:Diesel fuel is a primary candidate for use aboard submarines. It has a high energy density and it is already in the Navy inventory. Fuel cells are attractive for submarines from an energy density perspective. Unfortunately, in hydrocarbon reforming power systems, the fuel cell power density is… more
Abstract:DESCRIPTION (provided by applicant): Many areas of biomedical research have benefited greatly from recent progress in mass spectrometry instrumentation and techniques. Time-of-flight mass spectrometry, in particular, has emerged as an important tool in molecular biology and biomedical research and… more
Abstract:DESCRIPTION (provided by applicant): Mass spectrometry has become an essential analytical tool for clinical diagnostics, drug discovery, and similar biomedical research areas, due in large part to its ability to elucidate the structure of biological molecules. Such information is commonly derived… more
Abstract:We propose to development of a relatively low cost, flexible, and environmentally sensitive means for shock qualification testing major shipboard systems using a non-explosive energetic source to generate the dynamic time-history environment representative of UNDEX situations. The key aspects of… more
Abstract:Currently no commercially available voltammetric electrode system exists which can operate in the water column, water/sediment interface or sediment. These electrodes need to sense a variety of electroactive species in the marine environment, which are biogeochemical relevant to understanding the… more
Abstract:Robotic researchers currently are using insufficient and varying robot platforms to investigate issues crucial to the successful development of a remote reconnaissance tool for the urban search and rescue (USAR) community. USAR robotic researchers need a standard robot platform designed for research… more
Abstract:This Phase I Project will produce RABiTS-based YBCO CCs which are suitable for the manufacture of YBCO Coated Conductors with reduced AC losses. The improvements are based on a novel approach in the production of elements of the conductor. Anticipated AC losses will be analyzed for magnetic field… more
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