Abstract:DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of… more
Abstract:This SBIR Phase I project will lead to the development of a technology to detect very low levels of multiple pathogen-specific proteins or human proteins very quickly after exposure to biological warfare (BW) agents. The technology will link several proven techniques in a unique sequence so that a… more
Abstract:Excellatron Solid State, LLC (ESS) proposes an innovative lithium oxygen energy storage system focused on High Altitude Airship (HAA) applications. This project will result in battery technology that has the potential for: Â¿Specific capacity that is eight to ten times that of conventional… more
Abstract:DESCRIPTION (provided by applicant):
Phase I of this Fast-Track grant will successfully demonstrate a Mini-Mixed-Flow pump concept for a permanently implantable, extremely small right ventricular assist device (RVAD). The goal of Phase II is to develop and demonstrate a product prototype. The… more
Abstract:DESCRIPTION (provided by applicant):
Since 1990, lung transplantation has become the preferred clinical procedure for patients with end-stage lung failure due to such conditions as chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), idiopathic pulmonary fibrosis (IPF), and… more
Abstract:MTI MicroFuel Cells Inc. will undertake a study, which examines the current regulations and requirements (particularly transportation and military requirements) pertaining to the distribution logistics and user safety issues in regard to direct methanol fuel cell systems and the associated fuel… more
Abstract:DESCRIPTION (provided by applicant): Essential hypertension, or elevated blood pressure of unknown etiology, is responsible for more morbidity and mortality than the top five leading diseases. However, no diagnostic test exists for the prediction of essential hypertension. We have developed a human… more
Abstract:DESCRIPTION (provided by applicant): Phase I studies will investigate the safety and effectiveness of a novel, easy to use, non-invasive device, which mitigates erectile dysfunction (ED). This device, the Erectile Prosthetic Support (EPS) (U.S. Patent 6251067), utilizes a specially engineered… more
Abstract:The Joint Strike Fighter Program (JSF) will produce the most sophisticated warfighter in the history of military aviation. JSF is unique as a major weapons system acquisition program in that the economics of system operation, support and maintenance are being developed concurrently with the… more
Abstract:Controlling the functioning of wind tunnels at AEDC requires the measurement of the angular displacement of large air valves. Reliably sensing these valves positions has been problematic due to the large vibrations that are encountered; the sensors break frequently resulting in significant down time… more
Abstract:The Air Force is developing a wide variety of technologies for aircraft engine propulsion / engine health management (PHM/EHM). These technologies include; high frequency vibration for bearing monitoring, oil chemistry / condition, oil debris, and on-board life models, for example. Unfortunately,… more
Abstract:Modern technology has significantly impacted advanced fire alarm systems. As the sophistication of new devices increases, so has the quantity of data they are capable of collecting. However in current alarm systems only a small portion of the available information is used. Without the continuous… more
Abstract:The goal of the proposed research is to design, develop, test and demonstrate clinical use of a
head-mounted apparatus for visual field test. This low-weight, low-cost device will be a commercially viable, comprehensive visual field test platform based on virtual reality display technology.
Abstract:Intelligent Automation Systems, in collaboration with the Georgia Institute of Technology proposes the development of Self-Evolving Knowledge Base architecture. Specifically, this project will consist of 1) Analysis to identify maintenance related issues such as failure modes, criticality, etc for… more
Abstract:Soil sampling and laboratory analysis is inadequate to assess the spatial variability of agricultural soils. This project will develop an on-the-go system to measure and map several soil properties.
Abstract:76063-International initiatives are underway to reduce greenhouse gases in the air. The sequestration of carbon in agricultural soils is a candidate technology for achieving this reduction; however, more rapid and less expensive methods of measuring carbon in this sequestration scenario will be… more
Abstract:The Meshless Local Petrov-Galerkin (MLPG) methods will be developed for solving three dimensional nonlinear dynamic problems, with large plastic deformations, to simulate metallic and brittle materials under high-speed impact loads. The general MLPG approach will be applied to the system of… more
Abstract:The objective of the proposed research and development is to develop integrated computational algorithms, and attendant software, to treat fracture and fragmentation of brittle as well as ductile materials, using the Meshless Local Petrov Galerkin nmethod, which is a new pardigm in computational… more
Abstract:The primary means of de-icing steel or aluminum structures on ships today consists of physical removal of the ice by impact with sledgehammers and aluminum baseball bats. Due to the introduction of composite structures on Naval vessals, deicing methods are required that do not result in impact… more
Abstract:DESCRIPTION (provided by applicant) The high-resolution MRI techniques developed by the Principal Investigator, offer unsurpassed image contrast, are non-invasive, permit the acquisition of images in any desired plane without obscuring vision, and provide undistorted in vivo visualization of the… more
Abstract:75586-The development and wide application of fluorescence-based technology to the detection and monitoring of biomolecule interactions is limited by the signal produced by the probe, the size of the biomolecules, and the detection technology. Highly desired real-time detection, without washing… more
Abstract:Most of the 6 billion pounds of adhesives used in the United States each year are derived from petrochemicals; many still contain volatile organic compounds. Montana Biotech SE, Inc., has developed a process for producing a natural polymer with excellent adhesive properties. Tensile strength on… more
Abstract:The proposed work seeks to develop and optimize an electrode-less plasma propulsion system that is based on a high power helicon (HPH) that is being developed collaboratively between MSNW and the University of Washington. The helicon is well suited for this task, as it is known for efficient… more
Abstract:75650-For the plasma jet liner approach to magnetized target fusion, a plasma accelerator is required that is capable of launching a plasma jet with a mass of 0.2 mg to 0.4 mg and a diameter no larger than about 20 cm. In addition, the accelerator must be capable of attaining plasma/plasmoid… more
Abstract:DESCRIPTION (provided by applicant): Leishmania are typanosomatid protozoans that are transmitted by phlebotomine sand flies causing leishmaniasis. Leishmaniasis is a zoonosis and affects 12 million people in 88 countries, of which 72 are considered developing countries. It is estimated that 350… more
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