Abstract:DESCRIPTION (provided by investigator): Chronic infection with hepatitis B virus (HBV) is associated with a high incidence of liver diseases, including hepatocellular carcinoma (HCC). Hepatitis B virus x antigen (HBxAg), one of the four proteins encoded by the virus, stimulates virus gene expression… more
Abstract:The performance benefits to satellite communication and other systems employing an Electronically Steerable Antenna are numerous. These include rapid beam scanning, increased beam agility, the performance of multiple functions, lighter weight, no angular momentum impact during beam scan and… more
Abstract:We propose to develop a novel aircraft-based sensor system for early launch detection, typing, tracking and kill assessment. In addition to providing enhanced capabilities with respect to current aircraft-based sensors for long range detection over wide areas in clear sky and cloud obscured… more
Abstract:Several plume-hardbody handover algorithms under development by various investigators show promise in simulations for locating the missile body when the body is resolved or approximately the size of a pixel. Several scenarios involving liquid propellant missiles, such as the cases where these… more
Abstract:Phase II would utilize a RDTS sensor and three PSRS sensors to verify the concept and capabilities of an `over the water' intruder detection system. The proposed project would utilize multiple high-resolution radar sensors, with overlapping coverage zones, to detect surface targets. Each radar… more
Abstract:Penetrator bomb damage assessment is particularly difficult to perform since traditional visual reconnaissance methods do not reveal damage below the surface. The AFRL is currently engaged in developing a survivable, low-bandwidth transmitter that will be capable of real-time delivery of penetrator… more
Abstract:This Small Business Innovative Research (SBIR) Phase I project investigates a novel digital approach for modulation and demodulation of FMCW signals in precision radar systems and wideband radios. Recent availability of Silicon Germanium technologies supporting clock speeds of 10 GHz make possible… more
Abstract:DESCRIPTION (provided by applicant): The threats posed by agents of biological warfare have gained increasing attention in light of recent global events. Many early symptoms of infection by agents of biological warfare are indistinguishable from commonly observed diseases. For this reason, rapid,… more
Abstract:The Remote Minehunting System (RMS) AN/WLD-1(V)1 vehicle (RMV) currently does not have a forward-looking sonar (FLS), or any other underwater obstacle avoidance sensor. This means that the RMV itself, while towing a sonar array, will be "flying blind" in littoral environments that are expected to… more
Abstract:DESCRIPTION (provided by applicant): Fungal infections have increased dramatically in recent years to become important causes of mortality in hospitalized patients. The increase in life-threatening fungal infections has brought about an increased use of antifungal drugs and a pressing need for new,… more
Abstract:OmniSite Biodiagnostics, Inc. and its parent company, Systems and Processes Engineering Corporation (SPEC), have extensive experience in both microfluidic, micromechanical (MEMS) and Fluorescence detection technologies. OmniSite proposes to design and prototype a compact, handheld and low power… more
Abstract:Coherent Logix, Incorporated (CLX) proposes to develop a radiation-hardened, highly efficient, parallel digital signal processor (PDSP) integrated circuit. For non-radiation-hardened applications, CLX is developing a new, revolutionary, highly-efficient, ultra low power signal processor based on… more
Abstract:Coherent Logix, Incorporated proposes to develop a Hyperspectral Image Processing Platform (HIPP) that will be able process 30 hyperspectral cubes per second, where a hypercube is approximately 100 MegaByte (MB) in size. The platform will be reprogrammable and dynamically reconfigurable to support… more
Abstract:Coherent Logix, Incorporated proposes to develop a Hyperspectral Image Processing Platform (HIPP) that will revolutionize hyperspectral image processing systems with the capability to process a 128 Megabyte (MB) hyperspectral data cube at more than 30 data cubes per second while simultaneously being… more
Abstract:72731-Thermoelectric power plants account for 39% of the fresh water withdrawn from streams and lakes in the United States, second only to agriculture. 3.3 billion gallons daily are lost to evaporation and 190 billion returned as warm water discharge. The link between adequate supplies of low-cost… more
Abstract:The use of fluid counter-jets to disrupt the axial symmetry of armor piercing shaped charge warhead jets was demonstrated during the last century, but the research was limited in its scope to large cross-sections. The mass and bulk of these cross-sections restricted their suitability for fielding… more
Abstract:This proposed program seeks to develop, demonstrate, and commercialize a versatile new computer modeling approach for simulating and predicting the Battle Management, Command, Control, Computers and Communications (BMC4) operation and performance for the Ballistic Missile Defense System currently… more
Abstract:This proposed program seeks to develop, demonstrate, and commercialize a versatile new computer modeling approach for simulating and assessing the operation state of the information space in information networks. Currently there is a lack of tools for assessing the administration and operation of… more
Abstract:Theseus Logic, in partnership with FTL Systems, intends to integrate test and verification into their commercial design automation tool that will aid the designer by providing the means to automatically insert testability into clockless circuits. Success in this endeavor will eliminate one of the… more
Abstract:Theseus Logic, Inc. proposes a plug and play peripheral interconnect protocol that protects against obsolescence by using an asynchronous approach that does not rely on a specific clock rate. Additionally, an asynchronous approach provides robustness and flexibility that allows the same protocol… more
Abstract:75935-Conventional electron-cyclotron resonance (ECR) charge breeders, used to create beams of rare ion species as part of the DOE Nuclear Physics program, have gravitated towards higher frequencies and smaller plasma chambers. However, the smaller plasma chambers exacerbate the problems of plasma… more
Abstract:An overdue standardized and programmable chip level approach will move Space based DSP into ultra-efficient frequency domain vector processing and allow high resolution, high sample rate, and multi-dimensional signal and image processing with minimal power dissipation and minimal software… more
Abstract:The goal of this project is to develop a platform biosensor technology for rapid, multianalyte detection of proteins, peptides, nucleic acids, and other molecules of interest with sensitivity at the level of single molecule detection. We propose to build a hand-held, robust apparatus, similar to a… more
Abstract:DESCRIPTION (provided by applicant):
Scar formation is a problem of great clinical importance. Adult skin wounds heal with scar while early gestation fetal skin has the capacity to heal without scar. Using a fetal rat wound model, we have identified several endogenous molecules involved in… more
Abstract:This program seeks to develop a new approach for laser transmitters aimed at ultra-compact space-based Ladar systems. The technology proposed has the potential for reducing the size, weight and cost of the laser transmitter by an order of magnitude over existing devices with the same average power.… more
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