Abstract:In recent years, Structural Health Monitoring (SHM) is increasingly being evaluated by the industry as a possible method to improve the safety and reliability of structures and thereby reduce their operational cost. However, the scalability and applicability of SHM systems for the monitoring of… more
Abstract:DESCRIPTION (provided by applicant): Novel drugs that improve overall survival with decreased morbidity are critical in the war on cancer. Acenta Discovery Inc. has partnered with the Toretsky Lab of the Lombardi Cancer Center to create and preclinically evaluate novel inhibitors of the protein… more
Abstract:DESCRIPTION (provided by applicant): An important role for apoptosis has been established in various pathological processes, particularly in nervous tissues. Apoptosis essentially contributes to neuronal loss during normal development, after acute neuronal injury, and in chronic degenerative… more
Abstract:Intermediate and posterior uveitis cause 10% of blindness in the U.S. The mainstay of therapy is to eradicate the infectious cause and to quell the inflammation with corticosteroids or immunosuppressants. Delivery of anti-inflammatory drugs to the posterior portion of the globe in therapeutic… more
Abstract:As a cost avoidance measure against expensive replacement of certain life-limiting components of turbine engines, the Engine Rotor Life Extension (ERLE) program was conceived by the Air Force Research Laboratory (AFRL) to extend component life without increasing the risk of component failure.… more
Abstract:DESCRIPTION (provided by applicant):
Burn injuries represent the most terrifying and horrific trauma imaginable. This image is conditioned, in part, from the appearance of surviving bum victims that have been horribly scarred and disfigured following the healing of their injuries. Fortunately… more
Abstract:This STTR project will develop and validate a robust, scalable computational capability for the simulation of weapon-target interactions of interest to the Army. The proposed algorithm is based on the FLIP (Fluid Implicit Particle) - MPM (Material Point Method) - MFM (Multiphase Flow Method)… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to design and construct an ultra-high-resolution, high-precision phase-shift integrated measurement system suitable for metrology of advanced phase-shifting photomasks. A number of semiconductor manufacturers now expect to… more
Abstract:In 2003, The Nation¿s Report Card for educational progress showed that thirty-seven percent of fourth graders could not read at the most basic level. Further, poor readers are notoriously ¿disengaged¿ - they do not have the desire to read. These students need explicit instruction to improve their… more
Abstract:72216-This project will develop and demonstrate a seismic data processing technology that facilitates exploration in complex geologic areas, improves reservoir characterization for both oil and gas, increases the accuracy of estimating petrophysical attributes, and decreases the costs of exploratory… more
Abstract:3DGeo will implement a graphical user interface (GUI) built on top of the Globus Toolkit 3.0 (GT3) middleware and complying with the Open Grid Services Infrastructure (OGSI) standard. This GUI will be a convenient interface for computational resource discovery, computational resource monitoring, and… more
Abstract:76164-The economical production of natural gas from conventional and low permeability gas resources requires additional advances in exploration and production technologies. In particular, diagnostic and imaging technologies are needed to assess the effectiveness of new extraction techniques related… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop a grid-enabled environment where large multidimensional seismic data sets can be rapidly accessed, visualized, and interpreted by geographically dispersed users with heterogeneous local resources. The proposed work will… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will implement and demonstrate the feasibility of a new technology that enables enhance seismic resolution and imaging of deep water complex geologic structures by using variable azimuth wave-equation migration (VAWEM). VAWEM will… more
Abstract:Active Signal Technologies and Alfred University have brought together a broad-based industrial consortium to rapidly advance the development and commercialization of bismuth sodium titanate (BNT), a novel high performance capacitor material for use in both high-temperature and high-field… more
Abstract:Active Signal Technologies and Moog propose to demonstrate a solid state pulse width modulated pilot stage for a servo valve enabled by single crystal PMN-PT. The basic mechanism and labor intensive fabrication processes used to build conventional servo valves remain largely unchanged since the… more
Abstract:Active Signal Technologies proposes to further develop and field-test its innovative hand-held Brain Trauma Assessment System (BTAS) with the objective of equipping EMS providers to directly measure brain pathology with sufficient sensitivity to confidently triage patients. With current field… more
Abstract:The current tested and proven LBVDS system is limited in the platforms that can host it due to the large volume and weight requirements of the system. Active Signal Technologies proposes to retain the high power density features of the system, but modify it to retain as much performance as feasible… more
Abstract:The overall objective of this project is to develop an automatic adaptive testing system that rapidly identifies specific cognitive deficits to aid in medical and operational decision making. This system will greatly increase the usability of test systems developed under Army sponsorship during the… more
Abstract:DESCRIPTION (provided by applicant): Activity-based probes (ABPs) for broad protein families will be used to establish protein-based activity profiles for the diagnosis/prognosis/staging of breast cancer and identification of new markers that can be used for more rapid clinical testing. Breast… more
Abstract:DESCRIPTION (provided by applicant):
Activity-based probes (ABPs) for broad protein families will be used to identify novel protein targets and small molecule leads relevant to ovarian cancer. Because ovarian cancer is often asymptomatic during its early and most treatable stages, it is… more
Abstract:Since the feedstocks used to make LO materials are themselves the products of chemical reactions, they're susceptible to decomposition or further chemical reactions, for convesion to either - Recyclable feedstock for LO manufacture or - Beneficial use in other products by destroying their LO… more
Abstract:The objective of this Phase I effort is to design and simulate an innovative optical architecture for true, interactive-rate holographic video. Our novel technique takes a contrarian approach to existing multi-view and holographic video systems, which are typically crippled by "jailbar" dark… more
Abstract:We propose to create a prototype of a shape and structure capture system which can construct accurate, realistic three dimensional models of typical commercial and residential building interiors from video imagery taken with a freely moving handheld camera. A precision inertial motion measurement… more
Abstract:We propose to use the principles of projective geometry and image feature extraction, tracking, and matching techniques to construct accurate, detailed three dimensional models from imagery taken with a freely moving airborne or camera. We also propose to develop methods of detecting and segmenting… more
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