Abstract:DESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures of interest per organism. In order to obtain a single protein… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a new Light Detection and Ranging (LIDAR) detector system, which will measure signals over seven orders of magnitude with a digitization resolution of better than 1 percent (from a single laser pulse). The detector… more
Abstract:76295-Beam transport in inertial fusion induction accelerators requires reliable, compact, and low cost superconducting quadrupole arrays. To correct the field at the outer edges of an array, and to reduce the stray magnetic field to meet the requirements of the surrounding induction cores needed… more
Abstract:75824-Induction cores, used to accelerate the heavy ion beams in inertial fusion, are built around the outer diameter of the cryostat that houses the superconducting quadrupole array. A compact cryostat would be highly desirable for reducing the cost of the induction cores. Recent experience with… more
Abstract:75879-Hydrogen storage materials with a large capacity are needed to store, transport, and utilize hydrogen for fuel cells. This project will employ a unique combinatorial technique for rapidly screening a number of nanocrystalline alloys and intermetallics, in order to identify prospective… more
Abstract:M19 grade silicon steel is the most commonly used soft magnet for a number of applications such as in the manufature of motors. Advanced Materials Corporation proposes to fabricate new, proprietary magnet compositions and bonded magnets employing novel processing techniques. The saturation induction… more
Abstract:Advanced Materials Technology, Inc responds to the DoD needs to develop novel polymer-based materials for aerospace mirror applications in missile defense systems. Compared to the current state-of-art mirror materials, polymeric materials will provide considerable weight and cost savings. In order… more
Abstract:Advanced Materials Technology, Inc responds to the DoD needs to develop an innovative robust thermal insulation technology to insulate cryogenic temperature-sensitive space systems and components. Sensitive cryogenic structures and their subsystems need to be protected from direct solar heating,… more
Abstract:Advanced Materials Technology, Inc responds to the Navy need to develop novel blast packaging materials that will contain blast effects of an accidentally detonated weapon, namely MK84 bomb. The container should be lightweight and strong for ease of handling and must meet shipboard fire, smoke, and… more
Abstract:75859 Absorption refrigeration is the only currently available method that utilizes low-temperature waste heat to provide cooling. Unfortunately, absorption cooling systems for commercial and small industrial applications are relatively large and expensive, require costly-to-maintain cooling… more
Abstract:DESCRIPTION (provided by applicant): Over 299,000 total knee replacement procedures were conducted in 2002 with projections to 474,000 by 2030. It is estimated that the annual cost of TKR exceeds $6 billion in the US. Despite the success of TKR revision surgery accounts for between 8 and 9 percent… more
Abstract:This SBIR Phase II project is to continuously and fully develop the title parallel computational design tools initiated in Phase I into superpowerful, commercializable prototype design tools (computer codes) in the following manner: (i) adopting/extending our own superefficient Integral… more
Abstract:3TEX will build on the results of the Phase I projects funded by ONR to develop multi-functional composite material systems designed to both carry structural loads and provide blast protection. The emphasis in this proposed phase II effort will be on all composite solutions not involving metallic… more
Abstract:Thermal protection materials have been largely parasitic materials adhered to airframe structural materials beneath. Attachment of such disparate and largely non-load-bearing materials incurs weight penalties and encourages failures. Integrated preforms providing enhanced thermal management,… more
Abstract:Three-dimensional woven and braided fiber architectures provide important advantages to composites, including suppression of delamination, high damage tolerance, improved through-the-thickness properties, simplicity and cost-effectiveness of manufacturing complex composite structural components.… more
Abstract:Common screwdrivers graduate from a locally hard tip to a globally ductile shaft. Likewise, hybrid metallic molds have been produced which have conductive alloys in strategic locations leading heat to appropriate sinks. Fiber composite structures have also been made with more brittle high… more
Abstract:GFRP cored panels are common in current shipboard structure design. Robust and practical means of joining these and other composite materials to one another and to any substructure are critical to forming large structures. 3TEX will develop and test joining methods and materials based on 3WEAVETM,… more
Abstract:DESCRIPTION (provided by applicant):
Advanced Medical Electronics (AME) proposes to develop a combination infrared/visible light sensing augmented reality endoscope. This proposed endoscope will be suitable for use during surgical thermal treatment procedures (ablation) to accurately measure… more
Abstract:DESCRIPTION (provided by applicant):
Advanced Medical Electronics (AME) proposes to develop a combination infrared/visible light sensing augmented reality endoscope. This proposed endoscope will be suitable for use during surgical thermal treatment procedures (ablation) to accurately measure… more
Abstract:Due to environmental control requirements, the sources of separator materials for existing Ni-H2 batteries are discontinuing that business. During Phase I of this project, AMS developed an advanced battery separator technology that addresses this issue. Specifically, AMS developed a… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop an integrated microchip system for glycosylated hemoglobin (GHb). The approach adapts existing protocols for GHb detection using capillary gel electrophoresis and pulsed amperometric detection.
The commercial… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project concerns the use of time-lapse seismic P-wave and S-wave data simultaneously to obtain seismic monitoring images of fluid-flow saturation and pore pressure in subsurface reservoirs. Time-lapse seismic using P-waves alone may not always… more
Abstract:DESCRIPTION (provided by applicant):
This Phase 1 STTR project will determine the feasibility of using web services, based on standard SOAP/XML (HL-7) protocols, to exchange Emergency Medical Services (EMS) field data with disparate hospital information systems. It will build upon a pre-hospital… more
Abstract:DESCRIPTION (provided by applicant): Each year 200,000 women in the US are diagnosed with breast cancer, and 40,000 women will die of the disease. Serum diagnosis for screening breast cancer patients is not yet available. Moreover, there is only limited possibility for monitoring response to… more
Abstract:DESCRIPTION (provided by applicant):
Personalized medicine is a new clinical pardigm where a specific cancer therapeutic is prescribed based upon the individual biology of the patient. For example, specific receptor tyrosine kinase (rTK) inhibitors may be chosen based on the proteomic profile of… more
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