Abstract:76252S The detection of dilute radioactive xenon isotopes in the atmosphere is an important component of both national and international efforts to detect clandestine underground nuclear weapons tests. Pacific Northwest National Laboratory has developed an Automated Radioxenon Sampler/Analyzer… more
Abstract:78017S Verification instruments are required to assure that nations adhere to their promises not to develop or test nuclear weapons. To address this need, the DOE's Pacific Northwest National Laboratory has developed a Radionuclide Aerosol Sampler/Analyzer (RASA) that extracts sub-micron… more
Abstract:78226S For its nuclear non-proliferation and nuclear attribution efforts, the DOE requires highly sensitive instruments to accurately analyze the isotope ratios of uranium, plutonium and other radioactive elements in collected samples. Because existing gamma ray spectrometers do not have adequate… more
Abstract:DESCRIPTION (provided by applicant): The long term objective of this work is to develop a new technology for gamma-ray imaging cameras based on the combination of digital processing electronics and position sensitive avalanche photodiodes (PSAPDs). Gamma cameras are finding increasing applications… more
Abstract:DESCRIPTION (provided by applicant): The transplantation of heart grafts can dramatically provide a long and productive life to recipients with heart failure. Typical transplant survivals are more than 10 years. Because of an acute shortage of human donors, however, most do not receive their needed… more
Abstract:Future NASA programs like Tertiary Planet Finder (TPF) require high-density deformable mirrors with up to 16,000 actuators to enable direct imaging of planets around distant stars. Xinetics has been developing high-density module actuator arrays that will enable deformable mirrors to be fabricated… more
Abstract:Xinetics has demonstrated the technology required to fabricate a self-compensating highly adaptive silicon carbide primary mirror system having embedded actuators, sensors, and neural control with an areal density less that 10Kg/m2. The system architecture complete with feedback sensors, and neural… more
Abstract:Lightweight meter class aspheres had been limited to serial glass production prior to the advantages in cost, schedule, and production that were enabled using hybrid SiC and replicated nanolaminate technologies. The proposed program will extend the hybrid mirror advantages to all optical substrate… more
Abstract:Field emission electric propulsion (FEEP) thrusters have gained considerable attention for spacecrafts disturbance compensation because of excellent characteristics. The application of current FEEP has been slow in developing mainly caused by high specific power, which limit the milli-Newton… more
Abstract:79658B The reliable fabrication of high performance point electron sources is required for scanning transmission electron microscopy (STEM) systems with brightness greater than 109 Amp/cm2/steradian at an extraction voltage of 100 kV. Conventional point sources require a high vacuum for stable… more
Abstract:DESCRIPTION (provided by applicant): Substantial technological growth has spurred a new interest in imaging techniques, and their usage has grown considerably. High-resolution small animal imaging systems have emerged as important new tools for laboratory animal research. X-ray imaging is widely… more
Abstract:The conventional thermionic cathodes used in traveling wave tubes (TWTs) suffer from many technical limitations including limited current density, poor energy efficiency, difficulty of control, and lack of miniaturization. Xintek, Inc. has developed proprietary technologies for fabrication of high… more
Abstract:The exceptional properties of carbon nanotubes that have prompted potential applications rely on their atomic structure. While the sensitivity of nanotube properties on structural features has been extensively investigated through theoretical analysis and numerical simulations, in practice there is… more
Abstract:An unconventional, continuous, and flexible manufacturing process is proposed for the production of sodium iodide detectors. The steps of crystal growing and substantially simplified detector machining are integrated into one streamline process based on proven techniques with minimal capital… more
Abstract:DESCRIPTION (provided by applicant): Xoran Technologies has developed a dedicated, in-office, dentomaxillofacial cone-beam CT (CBCT) scanner through previous grants from the National Institute of Health. The scanner, formerly dubbed DentoCAT, has been recently FDA approved and is currently being… more
Abstract:DESCRIPTION (provided by applicant):
Image-guidance is revolutionizing many medical procedures by providing anatomical information and instrument position during interventions which, in turn, allows for minimally invasive techniques and access to ordinarily inaccessible parts of body. In many… more
Abstract:DESCRIPTION (provided by applicant): In-situ high-resolution 3D imaging of cell or tissue samples offers an important capability to biomedical researchers. It is particularly valuable when the observation can be made at a resolution approaching molecular level with samples that have undergone little… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop an in-vitro x-ray nano-beam irradiation system with 30 nm beam size and an integrated multi-mode visible-light microscope to precisely locate and irradiate sub-cellular organelles. This instrument is a valuable analytical tool for the… more
Abstract:DESCRIPTION (provided by applicant): X-ray based technology plays a critical and important role in healthcare and biomedical research. X-ray radiography is one of the most important and widely deployed medical diagnostic methods that can be traced back to the invention of x-rays more than 100… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project involves the development of a diagnostic and characterization tool with a spatial resolution at a nanometer scale that is critical to enable rapid commercialization of nanotechnology. The research involves developing an… more
Abstract:DESCRIPTION (provided by applicant): It is known that conventional anti-scatter grids are limited in their ability to control scatter in general radiography. In recent years this problem has been aggravated by the use of less efficient (thin, high line density, low lead content) grids, and the… more
Abstract:78242S Long-term and continuous monitoring of heavy metal contaminants in DOE tanks or DOE landfills has long been of great interest to DOE. Existing technologies either have the required detection sensitivity but are not field deployable, or are field deployable but lack the detection sensitivity… more
Abstract:75684S The evaluation of radionuclide and metal contaminants, found in the groundwater during the monitoring of DOE sites, is typically done off-site, using plasma mass spectroscopy or optical emission spectrometry. These analysis techniques are not suitable for automated field use because they… more
Abstract:Air particulate has been identified as a souce of primary and secondary health risks. Even small, short-term increases in the amount of air particulte contamination in the atmosphere can produce significant increases in both mortality and morbidity from respiratory and cardiovasulare diseases. For… more
Abstract:DESCRIPTION (provided by applicant): Measurements of the composition of body fluids (urine, blood, plasma) are among the most important tools for disease detection and control. One class of measurement, less routinely applied but of increasing importance, is determination of trace element… more
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