Abstract:DESCRIPTION (provided by applicant): The objective of this Phase I research is to demonstrate the feasibility of creating timed-bioabsorbable Pd-103 seeds for the treatment of prostate tumors. Timed- bioabsorbable seeds have the combined benefits of titanium seeds, high dose rate temporary seeds,… more
Abstract:This Small Business Innovative Research (SBIR) Phase I project aims at developing a compact high-throughput in-situ crystallography screening system that rapidly measures x-ray diffraction properties of crystals while inside the growth dish to monitor and optimize the growth condition. This project… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop an innovative x-ray fluorescence (XFi) imaging spectrometer with the following important attributes: (1) element specific imaging for nearly all elements in the periodic table, (2) high resolution: 30nm resolution… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop a Wolter capillary condenser for x-ray microscopy. Its successful development will improve the throughput of tabletop x-ray microscopes by 10 times and significantly reduces the system cost for wide deployment in biomedical laboratories.… more
Abstract:DESCRIPTION (provided by applicant): It is known that conventional anti-scatter grids are limited in their ability to control scatter in general radiography. In recent years this problem has been aggravated by the use of less efficient (thin, high line density, low lead content) grids, and the… more
Abstract:Air particulate has been identified as a source of primary and secondary health risks. More than 5000 air particulate monitoring stations have been established in the United States, mostly for measuring the total mass and the size distribution. Real-time monitoring instruments for mass and size… more
Abstract:State-of-the-art gas turbine engine bearing and gearbox steels are subject to significant rejection rates due to corrosion. Recent statistics from the engine overhaul depots indicate that greater than 50 percent of the bearings are rejected. Approximately 40 percent of these rejections are due to… more
Abstract:In Phase I XSB, Inc. explored the technical feasibility of building XcelLog - a user-centered deductive spreadsheet (DSS) system. XcelLog is envisioned as a tool for empowering end users to create intelligent computing applications using the spreadsheet metaphor without having to know programming.… more
Abstract:The project explores the feasibility of building Tiresias, a model-directed system empowering persons with visual impairments to conduct web transactions such as purchasing goods and paying utility bills online using non-visual modalities. Tiresias addresses current information overload problems by… more
Abstract:This proposal presents a secure, automated, field deployable Networked Sensor Array. Each array consists of many "Miniature Netted Sensors" (MNS). These sensors detect, quantify, encrypt and forward relevant situational information to Command and Control Units (CCU) and/or other designated… more
Abstract:Radar ducting behavior is a rather complex function of several environmental parameters into the atmospheric boundary layer but is dominated by humidity and temperature. Ideally, what is needed is a sensor that assesses real time vertical profiles of humidity, clouds and index/temperature and… more
Abstract:Reliable automated collection and measurement of precipitation from moored buoys has been an elusive goal. Operation of open aperture collectors on ocean platforms is problematic, requiring constant human attention and intervention to prevent sea spray from contaminating the collected samples, and… more
Abstract:Some of the challenges of manufacturing batteries for military applications are: low quantities, sporadic demand, high price and various power sources. If a Multi-Functional Cell Case for Metal-Air Batteries, such as Lithium-Air, Aluminum-Air, and Zinc-Air could be created, then it would be possible… more
Abstract:Lithium-ion (Li-ion) batteries are attractive candidates for use as power sources in aerospace applications because they have high specific energy ( up to 200 Wh/kg) and energy density ( 500 Wh/L) and long cycle life (1,000 ? 30,000 cycles currently depending on the depth of cycling). However, at… more
Abstract:This SBIR Phase I effort will be to construct and evaluate a high specific energy and high power lithium-air/ lithium-ion hybrid battery system. One of the challenges of incorporating metal-air batteries into existing equipment is the power requirements. Metal-air systems are typically very high in… more
Abstract:Lithium-ion batteries have been widely used and intensely investigated for the last decade. However, commercial cells have several problems including loss of power and capacity upon storage or prolonged use at elevated temperatures. In order to develop high-energy power sources for Army… more
Abstract:DESCRIPTION (provided by applicant): Y-Stress Inc., with the assistance of the George Meany Center for Labor Studies - National Labor College (GMC - NLC), proposes to create Safety E-Minders. The human mind can only absorb, retain and retrieve so much information. The more repetitions the better.… more
Abstract:DESCRIPTION (provided by applicant): Any vision of a world where the biomedical research community has access to a seamless network of fully integrated biomedical knowledge and experimental data is incomplete without the creation of an interface to deliver the information in the best possible way.… more
Abstract:DESCRIPTION (provided by applicant): The underlying hypothesis of this proposal is that inhibitors of ganglioside biosynthesis will prevent or slow the growth of neural crest-derived tumors (neuroblastoma, melanoma, astrocytoma). These tumor types produce an altered array of gangliosides that… more
Abstract:DESCRIPTION (provided by applicant): In accordance with the National Institute of Neurological Disorders and Stroke (NINDS) priorities, the goal of this proposal is to develop a system to discover drugs that have the potential to reduce scarring after spinal cord injury. In the United States,… more
Abstract:DESCRIPTION (provided by applicant): The underlying hypothesis of this proposal is that inhibitors of heparan sulfate biosynthesis will slow tumor growth. Genetic and pharmacological data has validated heparan sulfate as a novel anti-cancer target. This proposal describes a drug discovery program… more
Abstract:The United States Department of Defense (DoD) is responsible for millions of acres across the United States. At some DoD-owned sites (and those known as formerly used defense sites (FUDS)), it has been determined that subsurface contaminants exist. At many of the sites, trichloroethylene is a… more
Abstract:The fabrication of very large optical telescopes for space astronomy can be prohibitively costly due to the immense weight and size of monolithic primary mirrors. The cost of these telescopes can be reduced by the use of a segmented primary mirror. The next generation of large segmented mirrors… more
Abstract:This proposal addresses the testing and further development of a GPS low elevation jammer-nulling adaptive antenna system breadboard that was developed previously by ZA. The testing will determine its performance on ground-based platforms and the design modifications necessary for its… more
Abstract:Zel Technologies proposes an operational prototype of its Automated Course of Action (COA) Modeling (ACAM) Phase I feasibility demonstration to provide an automated means of developing friendly and enemy Courses COAs. ACAM augments Joint Intelligence Preparation of the Environment (IPE) tools with… more
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