Abstract:Zolo, in conjunction with researchers from Stanford University, proposes to develop multiplexed tunable diode laser spectroscopic diagnostics to measure combustion parameters in the flame holding region of jet engine augmentors. The proposed system will use wavelength modulation spectroscopy with… more
Abstract:Zolo Technologies and Stanford University's High Temperature GasDynamics Lab have teamed to propose the development of wavelength-multiplexed diode laser absorption measurements for a novel environment - the combustion zone of a liquid fueled rocket motor. A number of unique challenges will need to… more
Abstract:We propose to design and build a miniaturized pulsed terahertz (THz) sensing and spectroscopic system with the total system weight less than 5 lbs. The bandwidth of the THz system spans from 0.1 THz to 10 THz, and the system operates up to 10 MHz sampling rate and multi-kHz waveform scanning. The… more
Abstract:Reliable, high-sensitivity detection and identification of hazardous substances at stand-off distances is beyond the reach current commercial solutions, such as laser induced breakdown spectroscopy. To improve the possibility of detection and lower false alarm rates, spectroscopic techniques… more
Abstract:One of our most important national security missions is to detect and monitor nuclear proliferation activities at limited access sites over extended periods of time. In general, neither remote nor in situ measurements alone are adequate to characterize proliferation activities of interest;… more
Abstract:ZONA Technology proposed in Phase I a modeling and synthesis framework for the control of morphing elastic wing structures. The merit of the novel strategy to control in-flight large-scale geometrical shape changes while maintaining the overall vehicle stability and control, has been confirmed by… more
Abstract:ZONA Technology (ZONA) proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology that utilizes flight data with state-of-the-art control oriented techniques. The MUNSID toolbox augments the current match-point solution approach using the mu-analysis method… more
Abstract:ZONA Technology proposes in Phase I to develop a general methodology for the assembly of nonlinear reduced order models of the multiple contracting substructures that will likely provide the morphing of future vehicles. In addition it is proposed to extend the existing 2D… more
Abstract:ZONA Technology proposes a R&D effort to develop a Parameter-Varying Estimation (PVE) Toolbox that will rapidly evaluate and predict parameters that are required to certify an aircraft during flutter and store clearance expansion programs, as well as during flying qualities flight testing. The ZONA… more
Abstract:DESCRIPTION (provided by applicant): Natural product glycosylation is vital for the discovery of new pharmaceutical compounds. While it has been recognized for some time that many biologically active natural products owe much of their therapeutic properties to their glycosylation diversity, methods… more
Abstract:DESCRIPTION (provided by applicant): Carbohydrates play an important role in many cellular functions and diseases; however, carbohydrate-based drug discovery research is lagging compared to other biologically important molecules because of the significant challenges in creating and obtaining… more
Abstract:DESCRIPTION (provided by applicant): This Phase I proposal is to develop glycopeptide neoglycosides against VanA-resistant and VanB-resistant organisms. The clinical relevance of such compounds stems from the sharp rise in VRE (vancomycin-resistant enterococci, and more recently staphylococci)… more
Abstract:Zweave can deliver breakthrough solutions, which address the most significant business challenges facing U.S. manufacturers of uniforms, apparel, and footwear. Zweave's Phase I project revealed significant market demand for utilizing accurate 3-D anthropometric data in planning and design of… more
Abstract:Our objective is to develop a compact scanning Fabry-Perot spectrometer, for satellite far-infrared astronomy and Earth remote sensing, that operates at wavelengths of 100 ?m and longer, with a resolving power of 10,000 and free spectral range of 50 cm-1. The novelty of this innovation lies in… more
Abstract:The emerging field of terahertz imaging and spectroscopy offers great promise in physical security, military, drug enforcement and pharmaceuticals. Progress in THz applications awaits development of a high power THz laser, and a fast, sensitive focal plane array. Both of these are under… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project is to develop a high-resolution focal plane array for terahertz imagery. THz radiation is a largely unexplored region of the spectrum, but holds great promise for its ability to pass through clothing, packaging and baggage walls… more
Abstract:The deployment of US military forces often requires aircraft operations on runways of unknown construction, roughness, and load carrying capacities not only in UAS but also in foreign countries. Current FWD, DCP and RWD cannot satisfy the mission requirement. The air force is looking for an air… more
Abstract:DESCRIPTION (provided by applicant): Description: Several neurological disorders, including Alzheimer's disease and frontotemporal dementia with parkinsonism (FTDP) are characterized in part by neurofibrillary tangles made up primarily of the protein tau. While useful mammalian models of tauopathy… more
Abstract:DESCRIPTION (provided by applicant): Description: The goal of this research program is to develop a rapid, in vivo assay for screening small molecules for their ability to protect or regenerate neurons in a whole vertebrate organism. In Phase I, dopaminergic neurons in zebrafish embryos, made easily… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this Phase I proposal is to automate the analysis of the Z-Tag angiogenesis assay and to screen a small collection of compounds for their potential angiogenic activity. For the latter, we propose to screen two sets of compound libraries. First, a… more
Abstract:Zyvex in cooperation with Prairie View A&M (CARR) and Boeing will develop a space radiation shielding multi-functional material that will provide high energy radiation shielding required to protect astronauts on extended missions, strong enough to be used as an integral structural material and tough… more
Abstract:DESCRIPTION (provided by applicant): The objective of this project is to develop an adenoviral vector vaccine against HIV that is effective in stimulating cell-mediated immunity in animals previously immune to adenovirus The HIV vaccine will be used to protect against infection and to treat the… more
Abstract:Envision Engineering plans to bypass the issues associated with the traditional use of thermoset plastics in the development of functional large ground-based radomes by instead using thermoplastic materials and innovative manufacturing processes to create a functional radome design for a radar… more
Abstract:The ReSINE(TM) concept, for Remote Stand-off Impulse Neutron Examination, proposed by ER2S, Inc., is a unique application of three fairly mature technologies providing a compact mobile system for detecting 10 kg of hidden explosives at distances up to 100 m. First, it is based on the Short Pulse,… more
Abstract:A new high-performance multi-functional structural/energy storage technology is sought for airframes. To overcome the limitations of technologies develop by other organizations, ACM proposes to demonstrate a new all-solid technology that utilizes carbon fibers and high-temperature polymers. The… more
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