Abstract:DESCRIPTION (provided by applicant): The fight against cancer, heart disease, HIV, and all diseases are slow. Lives are being lost. The public spends over $1 trillion a year on health care. The government spends that much again. The tool used most in the fight against cancer employs fluorescent… more
Abstract:Automated vapor sampling detectors could potentially provide a detection capability for high vapor pressure explosives such as nitroglycerine (NG). However, for materials such as HMX and RDX, the equilibrium vapor pressures are at least four orders of magnitude lower than conventional… more
Abstract:The optically-cued electrospray aerosol selector (OCEAS), as proposed by MicroStructure Technologies (MicroST), and the Naval Research Laboratory (NRL), provide an innovative solution to achieving the challenging goals set by DHS. The goal of this project is to integrate an OCEAS design with a… more
Abstract:DESCRIPTION (provided by applicant): The overall aim of the proposed Phase II program is to complete the development and evaluation of a self-calibrating, low-cost Handheld Digital Microwave Radiometer that can non-invasively measure subsurface temperatures by simple contact with the human body in… more
Abstract:DESCRIPTION (provided by applicant): Phase I The current proposal describes the selection of an aptamer that recognizes the drug PD173955, which is one of large family of substituted pyrido[2,3-d]pyrimidine inhibitors of tyrosine protein kinases. An aptamer is a single stranded nucleic acid that… more
Abstract:Landfills and waterway are inundated with tons of non-degradable plastics derived from petrochemicals. An unusual polysaccharide has been identified which can be extruded as a biodegradable plastic. Unique properties allow it to replace certain petroleum-based plastics while already meeting the… more
Abstract:The Electrodeless Lorentz Force (ELF) Thruster is based on recent laboratory results on the formation and acceleration of magnetized plasmoids. The goal of the proposed research is to build and test a prototype that has the potential to surpass all current electric propulsion systems in efficiency,… more
Abstract:The overall goal of this Phase II project is to develop the Nanobreathr detection system for proximity detection of explosives at 50 meters, and specifically detection of peroxide improvised explosive devices (IED's) such as TATP and HMTD. Pentagon statistics show that about half the U.S. battle… more
Abstract:The Army seeks significant improvements in the protection of military targets through its use of infrared obscurants (IROs). Specifically, it calls for an order of magnitude improvement on the infrared extinction coefficient, while also minimizing costs. Existing obscurant technologies with… more
Abstract:This proposal describes the development of an on-board planning module for coordinated search and tracking (CSAT) using low-cost (~50 lb class) UAVs. The NTC/MIT Phase I CSAT system, based on Robust Distributed Task Assignment (RDTA), has been tested in a unique communication emulation environment,… more
Abstract:The goal of this proposal is to Design, fabricate, and demonstrate a low optical loss polymer directional coupler modulator with a total insertion fiber to fiber optical loss of less than 6 dB, has a high speed of greater than 20 GHz and a drive voltage (Vp) of less than 1 Volt. We will employ… more
Abstract:The objective of this proposal is to develop innovative highly reliable HPOA for free space laser communications based SATCOM operating over broad ranges of temperatures and of radiation environment. The Phase I effort is focused on investigating the feasibility of manufacturing of such a HPOA by… more
Abstract:Thrombolytic treatment with plasminogen activators (PA) such as tissue plasminogen activator (tPA) has been used not only for treatment of acute myocardial infarction, but also peripheral arterial occlusion (PAO). However, the risk of life-threatening intracranial hemorrhage is measurably high (0… more
Abstract:The performance benefits to satellite communication and other systems employing an Electronically Steerable Antenna are numerous. These include rapid beam scanning, increased beam agility, the performance of multiple functions, lighter weight, no angular momentum impact during beam scan and… more
Abstract:Broadband, true time delay phase shifters based on MEMS switches provide the high instantaneous bandwidth desired for applications such as multi-frequency antenna arrays with multiple functions such as radar, communications, and ECM. MEMS based phase shifters offer significant performance advantages… more
Abstract:This Small Technology Transfer Research (STTR) Phase I project aims to develop a microarray platform for micro-RNA profiling. The project will address the parameters that are required for optimal probe design and hybridization. Further, the project will design and test a microarray to profile miRNA… more
Abstract:DESCRIPTION (provided by applicant): Leptomeningeal carcinomatosis (LMC), a state of metastatic tumor invasion of the cerebrospinal fluid (CSF) space, carries a poor prognosis with short survival averaging 2-4 months. Currently the diagnosis of LMC is based on cytology demonstration of unequivalent… more
Abstract:S&K Technologies proposes to develop a storyboard tool to assist with the generation, verification, and refinement of storyboard information and its subsequent translation into model data for systems analysis and design tools. The most important contribution is an improved communication of the… more
Abstract:As the BMDS evolves over the next decade, the community will be exposed to a substantially greater amount of data from successful intercepts in all phases of the tiered defense, including boost, mid-course and terminal. In order to perform the necessary battle management, command and control… more
Abstract:The objective of the proposed effort is to develop and deliver a real-time physics-based simulation capability for predicting threat plume signatures from launch to burnout. SciTec's approach is to address the dominant phenomenology in each altitude regime (e.g. data derived mixing of free stream… more
Abstract:This proposal will develop methods to determine the weapons type associated with Ballistic Missile Defense engagements. This development will use impact and debris track observations from active RF and passive EO/IR sensors. The goal is to increase efficacy and accuracy for which individual objects… more
Abstract:Sonatech proposes to continue the development of the operational concept for an underwater "GPS-type" acoustic positioning system (UWAPS), to be deployable from surface craft or hovering helicopter, and to provide multiple users the ability to navigate with GPS precision underwater. UWAPS has… more
Abstract:This research focuses on fully developing energy density sensors that will yield a significant benefit both for measurements of interest to NASA, as well as for general acoustic measurements. Previous research has developed prototype energy density sensors. The Phase I research focused on developing… more
Abstract:DESCRIPTION (provided by applicant): The primary objective of this grant is to refine and test a prototype of the Comfort Condom(tm): a new condom made from silicone, a material that may offer better sensation and be less prone to breakage than latex or plastic. The Comfort Condom will feature… more
Abstract:Coherent Logix, Incorporated (CLX) proposes to develop a multi-chip module (MCM) for hyperspectral image processing and other high-throughput signal processing applications requiring ultra-low-power, extremely high performance, and very small form factor. Hyperspectral image processors (HIP) are… more
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