Abstract:The Navy is in need of a compact, passively Q-switched microchip laser, with long pre-use life, for deployment on missile systems. Our solution is a diode-pumped Nd:YVO4 - Cr:YAG microclip laser, constructed as a monolithic laser subassembly contained in a 14-pin butterfly package. The pump diode… more
Abstract:During Phase I, we experimented with several transition approaches and ran into three hurdles: 1) No matter how good the method for transitioning technology, if the development process has not been well-managed, there will be no technology to transition; 2) Transition does not happen without an… more
Abstract:Maintenance tag-out is a procedure that is part of many maintenance actions that happen daily whether onboard a ship in a maintenance depot or even a manufacturing environment. Typically, this is a manual and paper-based task that consumes considerable time and effort. Our vision is to create a… more
Abstract:Our vision for Automated Work Package generation is the innovative combination of the in-the-moment gathering of the proper data, information and knowledge as well as the proper presentation of that data in a useful and meaningful way that helps the maintainer accomplish a job. The need is for the… more
Abstract:The proposed program is for the development of a fundamental-mode S-band multiple-beam klystron (MBK) circuit and collector compatible with an eighteen-beam electron gun presently under development. The feasibility of the circuit to operate as a broadband high-power amplifying component when used in… more
Abstract:A sheet-beam vacuum electronic device (VED) is proposed as a potential compact THz power source for bridging the gap between low-power photonic sources and large-size, high-voltage sources. The Phase-I key objective is the demonstration via advanced computer codes of feasibility of the formation and… more
Abstract:The proposed effort is to evaluate the feasibility of a W-band sheet-beam vacuum electronic device that can provide up to 1 kW of peak RF power at a minimum efficiency of 20%. Key elements of this effort are on the generation and transport of the sheet beam and its interaction with the RF circuit.… more
Abstract:The Air Force needs a compact high-speed high-power spindle to rapidly manufacture complex geometries in aluminum and titanium aircraft structures. We propose to continue developing a compact high-speed high-power spindle to meet Air Force requirements. In Phase I, we designed a pre-prototype… more
Abstract:NASA needs a cryogenic refrigerator for the 15-25K range for receiving arrays of ground-based antennas that will serve the telecommunications needs of future space exploration. We propose to develop a 15-25K Static-Helium Regenerator/Double Pulse Tube Cooler for receiving arrays. Our SHR/DPTC… more
Abstract:The Navy needs a compact drill with controlled powerfeed for drilling holes in limited access areas of aircraft structures. We propose to adapt technology we are developing for a compact high-speed high-power milling spindle to develop a compact powerfeed drill for the Navy. Our drill uses compact… more
Abstract:DESCRIPTION (provided by applicant): The goals of this project are to develop, evaluate, and disseminate an Internet (web) application, Moderate Drinking (MD). MD will use a behavioral self-control training (BSCT) protocol that helps drinkers learn skills to either moderate their drinking or to… more
Abstract:DESCRIPTION (provided by applicant): Highly potent, orally active, metabolically stable, long-lived opioid agents for the treatment of alcoholism that have decreased side effects such as nausea, addiction liability, immunosuppression and respiratory depression represents a great unmet need. While a… more
Abstract:DESCRIPTION (provided by applicant): Dissemination of evidence-based therapies remains a high priority at NIDA. A number of barriers limit accessibility to evidence-based therapies in routine clinical settings. Substance use disorders (SUDs) co-occurring with borderline personality disorder (BPD)… more
Abstract:DESCRIPTION (provided by applicant): Interpersonal Psychotherapy (IPT) is one of the most thoroughly validated psychosocial treatments for depression. Dissemination of IPT, however, has been hindered by lack of trainers and didactic materials. Though several excellent textbooks regarding IPT are… more
Abstract:DESCRIPTION (provided by applicant): Dissemination of evidence-based practices remains a high priority at NIDA. A number of barriers limit accessibility to these effective practices in routine community-based treatment settings. Persons with severe and persistent mental illness (SPMI) commonly… more
Abstract:The purpose of the proposed project is to increase the "visibility" of juvenile desert tortoises at a distance by using "tags" that transmit their location and identity to readers using RFID, harmonic radar, or other radar technologies. We propose to accomplish this by using two or more of these… more
Abstract:DESCRIPTION (provided by applicant): There are over 500 protein kinases in the human genome and several hundred other enzymes that utilize ATP as a phosphate donor or energy source. Protein kinases are the second most intensively screened target class, with links to all of the major therapeutic… more
Abstract:DESCRIPTION (provided by applicant): Methylation is a ubiquitous covalent modification used to control the function of diverse biomolecules including hormones, neurotransmitters, xenobiotics, proteins, nucleic acids and lipids. More than 50 distinct methyltransferase (MTs) enzymes are present in… more
Abstract:Recreation trails are a key component of the social, economic and health of rural communities. People with mobility impairments are often excluded from trails, shared-use paths, parks and other public areas where barriers are erected to prevent access by motorized trail vehicles (MTVs), to control… more
Abstract:Abstract The Navy intends to develop distributed fields of underwater sensors devoted primarily to ASW. These fields may include stationary nodes and/or mobile nodes, but will have the need to move data among the nodes in the field and to reconfigure the system to respond to an evolving threat… more
Abstract:The overall goal of this research work is to design, build and evaluate high performance above-knee prosthetic systems suitable for military specific maneuvers. Existing above-knee prostheses are limited by the lack of compact energy sources, actuators, power regeneration methods, and control… more
Abstract:This effort is concerned with improving aircraft battle damage collection through systematic collection and documentation of battle damage sustained by aircraft. Accurate damage collection is an integral part of aircraft survivability, since much can be learned through its examination and… more
Abstract:The Air Force is interested in substantially improving the productivity of their unmanned aerial vehicle (UAV) radar systems to provide all environment detection of targets as well as detection and tracking of air and ground threats. SAR/GMTI radar systems deployed on mini-UAVs are expected to be… more
Abstract:The goal of signature prediction is to provide electromagnetics modeling to support detection and identification technologies for a wide range of target configurations and sensor characteristics. Signature prediction technologies have been extensively developed by AFRL, leading to a suite of… more
Abstract:DESCRIPTION (provided by applicant): Solid-phase oligonucleotide (ON) synthesis produces a complex mixture that contains, in addition to the target sequence, a plethora of other ONs and by-products. Purification is necessary to isolate the desired sequence from these other oligonucleotides.… more
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