Abstract:DESCRIPTION (provided by applicant): Cardiovascular disease is the number 1 killer in the United States and much of the Western world. Treatment of the disease costs billions of dollars each year and the costs continue to rise exponentially. Many strides have been made toward improving behavioral… more
Abstract:DESCRIPTION (provided by applicant): Currently, an estimated 8 million Americans have substantial kidney impairment and this number is growing. More people die annually from kidney failure than from either colon cancer, breast cancer, or prostate cancer. Estimated medical and other economic costs of… more
Abstract:DESCRIPTION (provided by applicant): Project Summary. The overall goal of this research program is to develop a novel magnetic resonance (MR) image analysis method that can distinguish between malignant and benign lung nodules in patients who are undergoing diagnostic evaluation for lung cancer. 3TP… more
Abstract:According to the Environmental Protection Agency, federal, state and local governments and private industry will spend billions of dollars annually over the next several decades to clean up groundwater sites contaminated with hazardous waste and petroleum products from a variety of sources. As many… more
Abstract:DESCRIPTION (provided by applicant): Tumor markers, measured in peripheral blood, could assist in diagnosis and management of non-small cell lung cancer (NSCLC) and potentially improve historically dismal outcomes. Circulating antibodies, generated to a wide range of tumor-associated proteins, can… more
Abstract:DESCRIPTION (provided by applicant): The ultimate aim of the proposed research is to provide a new and practical methodology for improved preservation of neural tissues by means of vitrification technology under development at 21st Century Medicine. In phase 1, a range of cryoprotectant formulations… more
Abstract:DESCRIPTION (provided by applicant): Summary: A laser-based acoustic emission (AE) detection device is proposed for work site structural stability assessment. This new device will take advantage of innovations in laser ultrasonics, artificial intelligence
(Al) and advanced acoustic emission… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to extend the current high frequency limit of acoustic analysis by two orders of magnitude and facilitate numerical simulation of extremely large sound structure interaction problems. The proposed method will advance the state of… more
Abstract:Helicopter operations in low visibility conditions and sling load operations continue to add risk to aviation operations. If slingloads could be picked up without the need for a ground crew, lives could be saved. In addition, a sensor that can detect the location of a load would help in low… more
Abstract:Future NASA architectures and missions will involve many distributed platforms that must work together. This in turn requires guidance, navigation and control (GN&C) technology such as systems that determine spacecraft relative range and attitude. The proposed Hybrid Guidance System (HGS) will be… more
Abstract:Understanding that saving weight without sacrificing performance on a vehicle is important, the objective of this program is to demonstrate lightweight materials (1.1-1.6 gm/cm3) materials that can replace Beryllium in the near term for multiple applications. These applications will have specific… more
Abstract:Understanding that saving weight without sacrificing performance on a vehicle is important, the objective of this program is to demonstrate Advanced lightweight materials (1.4-2.2 gm/cm3) materials that can have Radiation Hardened capability. These applications will have specific requirements of… more
Abstract:This Phase II program is developing NET Shape components from Encapsulated Powders. Significant advances in Phase I for various materials and in net shape processing techniques have been realized. The objective of Phase II is to continue fabrication of these unique materials and compare multiple… more
Abstract:The proposed STTR is the combination of a small business with unique materials experience, and Northwestern Unviersity, with expertise in Mirror applications, processing and characterization. The combination of these two entities with various prime contractors providing assistance makes for a… more
Abstract:The Air Force seeks a large production wind tunnel seeding system with full field steering capability. Additionally, the system must offer control of the particle size and density along with minimal maintenance and flow disturbance characteristics. These features will increase tunnel productivity,… more
Abstract:This SBIR is to develop advanced rotorcraft aerodynamic modules to significantly enhance and improve the analytical prediction of rotorcraft performance, stability, dynamic response, and loads to support vehicle design, manufacturing, operation, and flight testing. The research and development will… more
Abstract:The objective of this proposal is to develop a tool for time-accurate simulation of coupled CFD and multibody dynamics of tanker vehicles and sloshing liquid payloads, that includes integrated pre-processor, solver, and post-processor. The pre-processor allows constructing an object-oriented… more
Abstract:Shape analysis of pulses collected from arrays of fast particle detectors used in nuclear physics experiments requires data processing systems with fast (>500 Ms/s) sampling rates, in order to preserve the pulse shape information. Existing systems rely on multi-channel analog-to-digital converters… more
Abstract:Current ultra highspeed networks carry massive aggregate data ¿ows that must be monitored and processed to detect and counteract intrusions. The problem is further compounded by the sheer number and complexity of attacks. As a result, the challenges of intrusion detection in… more
Abstract:Sub-picosecond-resolution time-to-digital converters are needed to satisfy the requirements of time-on-flight measurements for the next generation of high energy and nuclear physics experiments. The converters must be highly integrated, power effective, and low cost, and feature plug-and-play… more
Abstract:Current and future programs of near-Earth and deep space exploration require the development of robust serial data transfer electronics within the spacecraft's subsystems while preserving open system architecture. The electronics must be reconfigurable, fault-tolerant, and have the ability to… more
Abstract:Advanced Scientific Concepts has developed a compact, flash ladar 3D camera. It's very small size makes it well suited to the serpentine robot. It is not a scanning ladar, but instead takes a 128x128 pixel image with a single flash of laser light and can acquire 30 frames per second. Photographs… more
Abstract:WHO estimates that between 300 and 500 million new cases of malaria occur each year and annual deaths from the disease number between 2 and 3 million. Although there are several compounds known to be effective for treating malaria, including quinine, doxycycline, primaquine, azithromycin, and… more
Abstract:DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is… more
Abstract:The objective of this project is to develop and validate a CAD tool for the rapid design of mechanically fastened repairs, bonded repairs, and hybrid repairs involving both adhesive bonding and mechanical fasteners. To allow use by non-specialists, the CAD tool will replace the current process of… more
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