Abstract:…nstrument for flight analysis. A low-resource and power consumption micro-sized GC detector that is proposed for development in Phase II of this project is based on a technology of Penning Ionization Electron Spectroscopy in plasma (PIES). Adding another analytical dimension to… more
Abstract:… demonstrate a micro-optical distributed sensor technology for temperature, pressure and strain measurements. The measurement principle is based on the detection of optical mode shifts of dielectric micro-beads that serve as sensors. The sensors are weakly coupled to one or… more
Abstract:DESCRIPTION (provided by applicant): Despite recent advances, CLL as the most common leukemia remains largely incurable disease. The goal of the proposed project is to elucidate the ability of the lentiviral vector (LV) to provide efficient and clinically feasible delivery… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this proposal is to evaluate the novel concept whether using lentiviral-engineered T cells that express chimeric receptors and signaling modules will improve efficacy for cancer immunotherapy directed against mesothelin.… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this proposal is to evaluate the novel concept whether using lentiviral-engineered T cells that express high affinity T cell receptor (TCR) capable of recognizing the tyrosinase:368-376 epitope, a melanoma/melanocytes… more
Abstract:DESCRIPTION (provided by applicant): The goal of the proposed project is to generate the pre-clinical data necessary to provide proof-of-principle for future clinical studies of pro-apoptotic lentiviral vector (LV) gene therapy using small hairpin RNA (shRNA) to target… more
Abstract:… wrapping an implicit surface around data points using the level set method. No assumptions about connectivity of these points is needed. New multiresolution techniques for speeding up the algorithm, reducing storage requirements, including information about the normals to the… more
Abstract:DESCRIPTION (provided by applicant): The death rate due to respiratory disease has increased nearly 20% in the United States since 1979, surpassing virtually all other types of disease. Adult respiratory distress syndrome (ARDS) alone afflicts approximately 150,000 patients… more
Abstract:…defined serial or RF key. Attempted unauthorized access would then result in initiation of data destruction process. (d) Extended Timing - self destruct auto-initiates if the device is not recovered or accessed within a predetermined time. This technique is similar to item b… more
Abstract:This SBIR will develop a new class of computer architecture called an "agent based computing" module (ABC Machine) that enables "cognitive computing" algorithms to be implemented effectively on a large scale. The ABC Machine is a biologically inspired architecture derived from… more
Abstract:… that will provide a threat representative radar return. This target will be an inflatable structure, which will be packaged around the exterior of the spacecraft bus and within the ESPA ring volume allotment. The payload will use the work hardening of aluminum to… more
Abstract:The use of micro-satellites to provide target complexes for BMD investigations can reduce program costs; targets would no longer need be launched every time a sensor test is desired However, the exoatmospheric flight of real threats lasts for only 20 minutes or so, while the… more
Abstract:Robust and reliable trace-gas analyzers (e.g., for isotopic carbon, methane, nitroxide, ammonia, etc.), suitable for long-term measurements, are not commercially available. Such analyzers are needed to achieve a better understanding of the global budget of these trace gases and… more
Abstract:This project will demonstrate 3D sensor capability to identify and track maritime targets, collect target characteristics that enable quick development of identification (ID) templates for ID and tracking of new targets, apply the technology to currently deployed naval passive… more
Abstract:Individuals with cognitive disabilities represent one of the fastest growing disability groups in the U. S. The potential for computer technology to increase social integration for this population is well-documented. However, cognitive and financial barriers frequently… more
Abstract:DESCRIPTION (provided by applicant): Benign prostatic hyperplasia (BPH) refers to the enlargement of the prostate gland, which occurs in 50% of 60-year old men with increasing incidence with age. This unchecked growth is most likely caused by dihydrotestosterone (DHT), and it… more
Abstract:… As more proteins are identified from the genome-sequencing projects, there is an increasing need for reliable and cost efficient means for expression and purification of proteins of academic and clinical importance. LifeSensors has developed a novel SUMO-fusion system to… more
Abstract:… yield of expressed proteins because the fusion is cleaved by the host enzymes and/or the tag does not have sufficient chaperoning effects. Although intact SUMO fusion system can significantly improve production of recombinant proteins in E. coli, it is not applicable to… more
Abstract:This Small Business Innovation Research Phase II project is designed to develop and optimize a prototype chrome-free solvent-free zero VOC ultraviolet (UV) light curable self-priming environmentally compliant multifunctional aircraft protective coating to satisfy all… more
Abstract:This Small Business Innovation Research Phase II project is designed to develop and optimize a prototype environmentally friendly isocyanate-free solvent-free UV curable hybrid resin system demonstrated in EPA SBIR Phase I research to have properties suitable for commercial… more
Abstract:The purpose of this NASA SBIR Phase I proposal is to develop a novel type of high resolving power diffraction gratings based on volume Bragg gratings technology. The key innovation to be used for creation of these gratings is the patented technology on production of high… more
Abstract:One of the most efficient ways to create narrow band filter is the use of reflective Bragg gratings or which allow increasing of efficiency and decreasing of weight compare to conventional technologies. OptiGrate have proved the concept of high efficiency narrow-band mirrors in… more
Abstract:…. Of particular interest is defense against worms, a highly problematic and dangerous threat because they self propagate and can rapidly debilitate a high-speed network. This project will design a high accuracy Intrusion Detection (ID) system that can scale to… more
Abstract:Over the past three years, Lightning Packs LLC has invented, developed, tested, and patented the innovative Suspended-load Backpack which extracts mechanical energy from the vertical movement of carried loads and converts it to unprecedented levels of electricity during normal… more
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