Abstract:Air Force operations often expose flight crew and support staff to unusual light-dark cycles that causes misalignment of the circadian pacemaker and sleep-wake cycles, resulting in disturbed sleep and impaired waking function. Air Force personnel are also frequently required to remain vigilant,… more
Abstract:DESCRIPTION (provided by applicant): Our research is focused on the potential of acid-prepared mesoporous silica (APMS) as a delivery agent for siRNA constructs to inhibit the ERK1/2 and ERK5 pathways in the treatment of human malignant mesothelioma (MM).
These pathways are critical to MM cell… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project aims to develop the technology for the manufacture of complex 3-D micro-devices from an array of metal and ceramic nanometer-scale particulates. In a novel lithographic gelcasting (LGC) process, multilayer molds will be made using… more
Abstract:DESCRIPTION (provided by applicant): We propose to investigate, design and manufacture a sophisticated, pre-production protein crystal detection microscope, the Crystal Finder(tm) microscope workstation, incorporating extinction polarization and quantitati
ve birefringence imaging for digitally… more
Abstract:This innovation is the design of a monochromatic x-ray source to be used in a mission compatible XPS spectrometer. Existing x-ray sources for XPS are large, require high power and a will have difficulty meeting the vibration specifications for a mission type instrument. The small x-ray sources… more
Abstract:Appareo Systems, LLC, proposes to develop a functional prototype head-mounted position and orientation system (HPOS). The HPOS will be capable of operating in electromagnetic fields of up to 200 volts/meter and will provide at least one degree of accuracy and at least one degree of resolution at a… more
Abstract:This SBIR Phase I project will focus on studying the chemistry and properties of a novel polymeric nano-layer coating, which is very rich in hydroxyl groups and made out of interwoven mono-dimensional strands which are chemically bound to the surface and occasionally to each other. The properties of… more
Abstract:This project extends Probability Bounds Analysis to model epistemic and aleatory uncertainty during early design of engineered systems in an Integrated Concurrent Engineering environment. This method uses efficient analytic and semi-analytic calculations, is more rigorous than probabilistic Monte… more
Abstract:This effort is a continuation of research work for SBIR PhaseI. The objective of this phase is to build prototype units for TranSphere SpeechAmbassador, a Portable Bilingual Speech Translation Device. TranSphere SpeechAmbassador will be a portable, wearable field translation device. It was… more
Abstract:Due to the phasing out of TNT usage in explosives due to safety and environmental concerns, insensitive explosives utilizing wax binders instead of TNT have gradually replaced TNT in bombs and other explosive shells. The wax material that has been the most utilized in this application has been… more
Abstract:Longer-lived stripper foils operating in present-day DOE accelerator facilities, with elements up to mass 100, would provide substantial operating savings and reduced radiation exposure to maintenance personnel. However, the next generation of rare isotope facilities would need even more robust… more
Abstract:Body wearable antenna systems designed for Land Warrior/Ground Soldiers are vulnerable to signal cancellations due to multipath and higher losses . Diversity and MIMO techniques integrated with these antennas can mitigate multipath and shadowing effects to increase the overall link system… more
Abstract:Numerical methods have proved very successful in low and mid frequency (VHF/UHF) regimes. However, these full wave methods are not efficient in handling electrically large problems dealing with radiation and coupling predictions for antennas on aircraft at higher frequencies (S/X/Ku/Ka bands).On the… more
Abstract:The formation and use of optical filaments resulting from high-power, ultrashort pulses propagating within the atmosphere is currently an active area of research for military and commercial applications. Optical filaments can be used to ionize molecules and atoms and produced related spectral… more
Abstract:"Global demands for red snapper have resulted in an unprecedented rise in mislabeling and substitution of the legally designated red snapper species, Lutjanus campechanus, with lesser-valued, related snapper species. Due to the immense popularity and high value of red snapper, economic fraud related… more
Abstract:The purpose of this project is to research and develop advanced multi-modal information technologies for knowledge capture and transfer that can feed a lessons-learned knowledge base for life cycle product development. In order to overcome the obstacles associated with current lessons-learned… more
Abstract:This innovative SBIR Phase II proposal plans to develop new multifunctional high temperature capable TCMS technologies based on the identified needs for the thermal control and ESD functions of the exploration mission hardware and also for the heat rejection system. These efforts can also serve… more
Abstract:For this SBIR Applied Media Analysis, Inc. is teamed with researchers at the University of Buffalo (SUNY Buffalo) to address the challenges of Arabic handwriting Optical Character Recognition (AHOCR). The proposed approach leverages our previous experience developing MATES, a Multilingual Automatic… more
Abstract:DESCRIPTION (provided by applicant): Applied Medical Visualizations (Medvis) proposes to create an interactive, World Wide Web based application for training providers of moderate sedation. The creation of a Web based training tool will allow providers of
moderate sedation access to a continuously… more
Abstract:DESCRIPTION (provided by applicant): The objective of this project is to develop and test information visualization display technology that will aid clinicians in diagnosing and treating unexpected events in critical care environments. Unexpected events oc
cur frequently in the ICU and many are… more
Abstract:DESCRIPTION (provided by applicant): Applied Medical Visualizations L.L.C. has developed a pharmacokinetic-pharmacodynamic display (PkPd Display) intended for anesthesia care providers. In Phase I, we designed a display that was based on a two drug interac
tion model, which was previously developed… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to fill a need in the arena of advanced monomolecular layers for specific surface functionalities. The project addresses a key limiting factor which prevents many novel biosensors, labchips and BioMEMS from reaching the market, i.e… more
Abstract:The present solicitation seeks new designs for an integrated visualization suite for analyzing large heterogeneous data sets relating to satellite and space programs. Applied Minds, Inc. (AMI) has developed a range of technologies that provide innovative data display and assist experts in analysis… more
Abstract:AMI seeks to continue its research into innovative software for forming ad-hoc teams, by collaborative support and enhancement of the People Finder software currently installed at AFRL. We will add features and functionality to the People Finder application that has taken us part of the way to… more
Abstract:The SBIR Phase II proposal aims to develop a prototype of an ultra-sensitive long-wave infrared (LWIR) focal plane array (FPA) based on the Phase I feasibility investigation. LWIR FPA is of great importance in space object detection and tracking. Issues of existing HgCdTe (MCT) and InSb FPAs… more
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