Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a new nanoscale characterization system which will be capable of identifying molecular species on the surfaces of materials or living structures, through their vibrational Infrared (IR) spectral signatures, with sub-100nm… more
Abstract:DESCRIPTION (provided by applicant): The importance of brain-derived G protein-coupled receptors (GPCRs) in mental function and health can hardly be overstated. However, our knowledge of the molecular biophysical basis for how GPCRs bind to their cognate
agonists and antagonists to elicit… more
Abstract:The objective of this proposal is to identify and integrate multi-echelon constraints in Manufacturing Repair Overhaul (MRO) process planning and scheduling. The OC-ALC depot operates in a multi-echelon MRO environment that is highly constrained regarding its capacities, resources, deadlines, and… more
Abstract:The main goal of this work is to develop a more reliable, robust, and accurate measurements of radome transmission properties. As a result, we propose a pilot study in order to design a two-horn testing system and provide several prototype radome testing measurements. The proposed two-horn testing… more
Abstract:Due to the significant decrease of aircraft parts across the U.S. military over past years, managing parts more efficiently has become a great necessity. The term managing suggests having the data resources available to predict, forecast events or determine an item's use such as the mission… more
Abstract:DESCRIPTION (provided by applicant): The objective of the proposed research is to develop and demonstrate Random Hand Hygiene Prompts (RHHP). RHHP will deliver voice messages at random times on a hospital floor, reminding listeners to perform hand hygiene.
Preliminary results suggest that listeners… more
Abstract:Andrews space proposes two pronged approach to reduce the size of elevation data files that need to be stored and transmitted. The first approach is a better compression algorithm that works well on discontinuous data although is less effective on smooth data. This is the opposite of traditional… more
Abstract:Andrews Space, Inc. proposes an innovative high altitude, long endurance (HALE) wing structural concept. The approach will be a careful optimization of the flexible and rigid structure to minimize mass. Additionally, a manufacturing feasibility study will be undertaken in order to determine if… more
Abstract:Aerobraking to reduce velocity for planetary capture and landing has long been assumed for use on Mars missions because Mars has an atmosphere, and the use of aerobraking minimizes the amount of propellants required from the Earth's surface. For Mars exploration missions, where large quantities of… more
Abstract:Andrews Space, Inc. proposes an innovative transpiration cooled aerobrake TPS design that is thermally protective, structurally flexible, and lightweight. This innovative design will meet launch volume constraints and satisfy terminal aerobraking requirements. The approach will focus on… more
Abstract:Reliable, high speed communications are critical to the successful completion of postulated missile defense engagements. Importantly, interceptor kill vehicles (KV) and carrier vehicles (CV) must meet mission performance requirements under hostile threat conditions and while exposed to direct and… more
Abstract:Reliable, capable, and radiation hardened control electronics are critical and needed for successful completion of postulated missile defense engagements. These electronics are used in motor controllers and divert and attitude control systems (DACS) for missile interceptors and space systems. The… more
Abstract:DESCRIPTION (provided by applicant): This proposal will establish proof of concept for the use of nitric oxide (NO) as an effective treatment for diabetic gastroparesis. The NO will be delivered using Amulet's NORTECH nitric oxide releasing technology. NOR
TECH delivers NO in a predictable and… more
Abstract:DESCRIPTION (provided by applicant): Acute liver failure (ALF) constitutes a challenge to clinicians and scientists alike. Commonly associated with the alcohol-acetaminophen syndrome, its clinical course is unpredictable and polarizing, with death as the o
utcome in a large percentage of cases.… more
Abstract:DESCRIPTION (provided by applicant): Progressive renal disease remains an unsolved challenge for the nephrologist, as it almost inevitably leads to end-stage renal failure, a life-threatening condition that necessitates renal replacement therapy. Few, if a
ny, of the currently practiced therapeutic… more
Abstract:DESCRIPTION (provided by applicant): Lung transplantation has become the mainstay of therapy for most end stage lung diseases including pulmonary emphysema, cystic fibrosis, and idiopathic pulmonary fibrosis. However, increasing demand for suitable donor l
ungs far exceeds the number of available… more
Abstract:DESCRIPTION (provided by applicant): Malignant glioma is the most commonly diagnosed primary brain cancer. Despite advances in diagnosis and therapy, these tumors show a high incidence of recurrence, have a poor prognosis and lack effective therapies. Rece
nt advances in tumor molecular biology have… more
Abstract:DESCRIPTION (provided by applicant): Scleroderma or fibrosis of skin caused by a surplus of extracellular matrix protein (collagen) is localized in the skin, or excess collagen may be collected in the kidneys, lungs, gastrointestinal tract, and heart. Scle
roderma affects approximately 400,000… more
Abstract:DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) is a chronic disease, characterized mainly by inflammation of the lining, or synovium, of the joints. It can lead to long-term joint damage, resulting in chronic pain, loss of function and dis
ability. Approximately 2.1 million people… more
Abstract:DESCRIPTION (provided by applicant): It is estimated that the annual incidence of spinal cord injury (SCI), not including persons who die at the scene of the accident, is approximately 11,000 cases per year. The number of patients currently affected by SCI
in the United States has been estimated at… more
Abstract:The proposed research effort recognizes the growing importance of open-source intelligence for evolving military operations, and is designed to enhance the capability of intelligence analysts to develop inferences from open information sources that can be acted on with confidence in the face of… more
Abstract:Phases I through III of this SBIR are about developing and implementing a new technology for creating "Tactical User Interfaces" (TUIs) that reduce manpower requirements and increase watchstander performance. Phase I applied this multi-faceted "TUI Technology" to passive sensors, especially ASW. … more
Abstract:Game-based training (GBT) has been touted as a promising medium for achieving improved training outcomes and heightened learner motivation, particularly in military training environments. However, there is little empirical research upon which to make informed decisions about when, where, or even if… more
Abstract:This project will develop an innovative training system to deliver advanced instruction in HQ staff officer competencies that will produce effective joint task force (JTF) teams. Stalwart (System of Training to Accelerate Learning in Joint Warfighting Teams) blends on-line training with small-team… more
Abstract:Phase I entails a systematic investigation of handheld devices and wiki-based information sharing in relation to the needs and requirements of PSYOP soldiers in order to produce an optimal design of the Mobile Intelligence Data Acquisition System (MIDAS). The investigation will thoroughly cover… more
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